SPHK1 regulates proliferation and survival responses in triple-negative breast cancer.
about
The emerging role of FTY720 (Fingolimod) in cancer treatmentCombination of RAD001 (everolimus) and docetaxel reduces prostate and breast cancer cell VEGF production and tumour vascularisation independently of sphingosine-kinase-1.Spontaneously-forming spheroids as an in vitro cancer cell model for anticancer drug screeningThe phosphorylated prodrug FTY720 is a histone deacetylase inhibitor that reactivates ERα expression and enhances hormonal therapy for breast cancer.Hepatitis B virus X protein promotes human hepatoma cell growth via upregulation of transcription factor AP2α and sphingosine kinase 1.Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells.A novel sphingosine kinase 1 inhibitor (SKI-5C) induces cell death of Wilms' tumor cells in vitro and in vivo.Metastatic triple-negative breast cancer is dependent on SphKs/S1P signaling for growth and survival.Overexpression of SphK1 enhances cell proliferation and invasion in triple-negative breast cancer via the PI3K/AKT signaling pathway.SphK1 promotes tumor cell migration and invasion in colorectal cancer.Inorganic Phosphate Prevents Erk1/2 and Stat3 Activation and Improves Sensitivity to Doxorubicin of MDA-MB-231 Breast Cancer Cells.miR-613 inhibits bladder cancer proliferation and migration through targeting SphK1.Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies.Metabolic Regulation of Apoptosis in Cancer.Comprehensive gene and microRNA expression profiling reveals a role for miRNAs in the oncogenic roles of SphK1 in papillary thyroid cancer.Melatonin prevents deregulation of the sphingosine kinase/sphingosine 1-phosphate signaling pathway in a mouse model of diethylnitrosamine-induced hepatocellular carcinoma.Host sphingosine kinase 1 worsens pancreatic cancer peritoneal carcinomatosis.Overexpression of sphingosine kinase 1 is predictive of poor prognosis in human breast cancer.Breast cancer sphingosine-1-phosphate is associated with phospho-sphingosine kinase 1 and lymphatic metastasis.Visualizing red blood cell sickling and the effects of inhibition of sphingosine kinase 1 using soft X-ray tomography.Senescent mesenchymal stem cells promote colorectal cancer cells growth via galectin-3 expression.Sphingosine kinase 1 in breast cancer.Sphingosine kinase 1 mediates diabetic renal fibrosis via NF-κB signaling pathway: involvement of CK2α.Insulin-like growth factor receptor and sphingosine kinase are prognostic and therapeutic targets in breast cancer.The Role of Sphingosine-1-Phosphate and Ceramide-1-Phosphate in Inflammation and Cancer.Triple Negative Breast Cancer Depends on Sphingosine Kinase 1 (SphK1)/Sphingosine-1-Phosphate (S1P)/Sphingosine 1-Phosphate Receptor 3 (S1PR3)/Notch Signaling for Metastasis.SPHK1 promotes metastasis of thyroid carcinoma through activation of the S1P/S1PR3/Notch signaling pathway.
P2860
Q26748927-63E1158E-A7FB-4426-ADA7-07710873F4D0Q33799125-C655B9D4-7F59-4E5A-9F94-AF840E0A9C97Q36356303-16573497-D0F2-4FE4-8153-4DA8BCF757E2Q36579794-FA665CC2-F7EB-4873-AE79-A2E612BFC8D2Q36746145-1C421EE9-5B1F-41DD-8E41-CDAA8D4721CCQ37190258-CDD8F2E3-0B3B-4F10-904D-18E5725DF2D2Q37448046-1AC84E49-A6E1-409D-B437-074BFD7D669CQ38720294-DF4DAB44-3811-4032-8693-450B8E779CDAQ38795539-A10D635D-9021-4750-8D5D-3C6CCC2B8F93Q38812061-DCF28F3E-F696-4C9F-BB97-D9F5615A4189Q38837835-9209F1FA-9E11-42E8-9B4F-3D490A7868E1Q38848862-D5F3A445-3A62-4DE5-96D0-C755C61FB4DFQ38909416-650EF02F-2D35-4501-9146-776CB516A5ECQ38969211-571BCF57-475A-4A1A-B3B3-136FDAA8D48BQ39109383-AD78763A-DACE-4DC7-8025-CB43BF16384DQ39328422-A0F31940-D628-4F0D-987C-BF98E420BE99Q40567317-1576ABC4-9D0C-4ED0-B16B-6D6B39CF1734Q40978323-5F66B3FF-25AC-4EE6-91DE-B7756FCB37E3Q41089511-A47FA732-8639-4AD6-9261-30AC0F717490Q41285267-86160643-0291-4FDA-857D-E5C3CE63E908Q42513473-381736E9-8F95-4B07-8DB8-6D718BCD5036Q45070648-A8A96484-8CC2-4957-92D0-27856345C082Q46377053-4B9ED216-A498-4CF9-9B4B-B3FA600BA6DDQ47117809-B8EFA4F7-C9BB-4E2B-8E36-7FB902CCC128Q47130227-7BDCCA3E-E6D1-40EC-8CB9-7BC8F4212F9BQ52615659-96FED57E-E79B-43DA-8EF0-D8A113318E21Q54978033-5D0D3338-3E92-444D-900B-CA3FF4FCE04A
P2860
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer.
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer.
@ast
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer.
@en
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer.
@nl
type
label
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer.
@ast
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer.
@en
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer.
@nl
prefLabel
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer.
@ast
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer.
@en
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer.
@nl
P2093
P2860
P356
P1433
P1476
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer.
@en
P2093
Alan Prem Kumar
Arpita Datta
Baohua Huang
Celestial T Yap
Jean Paul Thiery
Lingkai Wong
Ser Yue Loo
Sheryl S L Tan
Soo-Chin Lee
Tuan Zea Tan
P2860
P304
P356
10.18632/ONCOTARGET.1874
P407
P577
2014-08-01T00:00:00Z