In vitro characterization of ephedrine-related stereoisomers at biogenic amine transporters and the receptorome reveals selective actions as norepinephrine transporter substrates.
about
Trace amine-associated receptor 1 is a stereoselective binding site for compounds in the amphetamine classThe designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissueMephedrone, an abused psychoactive component of 'bath salts' and methamphetamine congener, does not cause neurotoxicity to dopamine nerve endings of the striatumThe rush to adrenaline: drugs in sport acting on the beta-adrenergic systemEvidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinilStudies of the biogenic amine transporters. 13. Identification of "agonist" and "antagonist" allosteric modulators of amphetamine-induced dopamine releaseCaveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Galphaq-coupled protein receptorsThe atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitorsNeuropharmacology of 3,4-Methylenedioxypyrovalerone (MDPV), Its Metabolites, and Related AnalogsCharacterization of a novel and potentially lethal designer drug (±)-cis-para-methyl-4-methylaminorex (4,4'-DMAR, or 'Serotoni').Pharmacology of novel synthetic stimulants structurally related to the "bath salts" constituent 3,4-methylenedioxypyrovalerone (MDPV).Evidence for noncompetitive modulation of substrate-induced serotonin release.Studies of the biogenic amine transporters. 14. Identification of low-efficacy "partial" substrates for the biogenic amine transportersAlpha-ethyltryptamines as dual dopamine-serotonin releasersStereochemistry of mephedrone neuropharmacology: enantiomer-specific behavioural and neurochemical effects in ratsStudies of the biogenic amine transporters 15. Identification of novel allosteric dopamine transporter ligands with nanomolar potencyThe new psychoactive substances 5-(2-aminopropyl)indole (5-IT) and 6-(2-aminopropyl)indole (6-IT) interact with monoamine transporters in brain tissue.Abuse-related neurochemical and behavioral effects of cathinone and 4-methylcathinone stereoisomers in ratsSynthesis, characterization and monoamine transporter activity of the new psychoactive substance mexedrone and its N-methoxy positional isomer, N-methoxymephedrone.Neurotoxicity Induced by Mephedrone: An up-to-date Review.Khat use and appetite: an overview and comparison of amphetamine, khat and cathinone.Distinct single cell signal transduction signatures in leukocyte subsets stimulated with khat extract, amphetamine-like cathinone, cathine or norephedrineStructure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET.Effects of MDMA and related analogs on plasma 5-HT: relevance to 5-HT transporters in blood and brain.Bath salts, mephedrone, and methylenedioxypyrovalerone as emerging illicit drugs that will need targeted therapeutic intervention.Cold but not sympathomimetics activates human brown adipose tissue in vivo.Psychiatric symptoms associated with ephedra use.Binding of the amphetamine-like 1-phenyl-piperazine to monoamine transporters.The potential adverse effects of habitual use of Catha edulis (khat).Psychoactive "bath salts": not so soothing.Ephedrine decreases vesicular monoamine transporter-2 function.Screening the receptorome reveals molecular targets responsible for drug-induced side effects: focus on 'fen-phen'.The potential impact of novel investigational compounds on human fertility.Powerful cocaine-like actions of 3,4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' productsMephedrone does not damage dopamine nerve endings of the striatum, but enhances the neurotoxicity of methamphetamine, amphetamine, and MDMAPharmacological examination of trifluoromethyl ring-substituted methcathinone analogsStudies of the biogenic amine transporters. 12. Identification of novel partial inhibitors of amphetamine-induced dopamine release.The novel recreational drug 3,4-methylenedioxypyrovalerone (MDPV) is a potent psychomotor stimulant: self-administration and locomotor activity in rats.Khat chewing from the pharmacological point of view: an update.Transport Reversal during Heteroexchange: A Kinetic Study.
P2860
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P2860
In vitro characterization of ephedrine-related stereoisomers at biogenic amine transporters and the receptorome reveals selective actions as norepinephrine transporter substrates.
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
name
In vitro characterization of e ...... phrine transporter substrates.
@ast
In vitro characterization of e ...... phrine transporter substrates.
@en
In vitro characterization of e ...... phrine transporter substrates.
@nl
type
label
In vitro characterization of e ...... phrine transporter substrates.
@ast
In vitro characterization of e ...... phrine transporter substrates.
@en
In vitro characterization of e ...... phrine transporter substrates.
@nl
prefLabel
In vitro characterization of e ...... phrine transporter substrates.
@ast
In vitro characterization of e ...... phrine transporter substrates.
@en
In vitro characterization of e ...... phrine transporter substrates.
@nl
P2093
P356
P1476
In vitro characterization of e ...... phrine transporter substrates.
@en
P2093
Beth A Compton-Toth
Bryan L Roth
John S Partilla
Jon Birkes
Richard A Glennon
Richard B Rothman
Richard Young
Sandra J Hufeisen
P304
P356
10.1124/JPET.103.053975
P407
P577
2003-09-03T00:00:00Z