Replication fork polarity gradients revealed by megabase-sized U-shaped replication timing domains in human cell lines
about
The replication domain model: regulating replicon firing in the context of large-scale chromosome architecturePeaks cloaked in the mist: the landscape of mammalian replication originsThe mutation spectrum in genomic late replication domains shapes mammalian GC contentUnderstanding spatial organizations of chromosomes via statistical analysis of Hi-C dataInferring the spatiotemporal DNA replication program from noisy data.A chromatin structure-based model accurately predicts DNA replication timing in human cellsTopologically associating domains are stable units of replication-timing regulationSystematic determination of replication activity type highlights interconnections between replication, chromatin structure and nuclear localization.Divergence of mammalian higher order chromatin structure is associated with developmental loci.A comparative encyclopedia of DNA elements in the mouse genomeHuman genome replication proceeds through four chromatin states.The spatiotemporal program of DNA replication is associated with specific combinations of chromatin marks in human cells.The hunt for origins of DNA replication in multicellular eukaryotesEmbryonic stem cell specific "master" replication origins at the heart of the loss of pluripotencyEvidence of selection for an accessible nucleosomal array in human3D chromatin conformation correlates with replication timing and is conserved in resting cellsMulti-scale structural community organisation of the human genome.APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication.Replication landscape of the human genomeBack to the origin: reconsidering replication, transcription, epigenetics, and cell cycle control.Genome-wide identification and characterisation of human DNA replication origins by initiation site sequencing (ini-seq).Best practices for mapping replication origins in eukaryotic chromosomes.Structural organization of human replication timing domains.Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand.APOBEC3A/B-induced mutagenesis is responsible for 20% of heritable mutations in the TpCpW context.Linking the DNA strand asymmetry to the spatio-temporal replication program. I. About the role of the replication fork polarity in genome evolution.Polymerase ζ Activity Is Linked to Replication Timing in Humans: Evidence from Mutational Signatures.Mathematical modeling of genome replication.High-resolution replication profiles define the stochastic nature of genome replication initiation and termination.Multiscale analysis of genome-wide replication timing profiles using a wavelet-based signal-processing algorithm.Epigenetic Transitions and Knotted Solitons in Stretched Chromatin.Revealing long-range interconnected hubs in human chromatin interaction data using graph theory.The eukaryotic bell-shaped temporal rate of DNA replication origin firing emanates from a balance between origin activation and passivation.Developmental and cancer-associated plasticity of DNA replication preferentially targets GC-poor, lowly expressed and late-replicating regions
P2860
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P2860
Replication fork polarity gradients revealed by megabase-sized U-shaped replication timing domains in human cell lines
description
2012 nî lūn-bûn
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2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Replication fork polarity grad ...... ng domains in human cell lines
@ast
Replication fork polarity grad ...... ng domains in human cell lines
@en
Replication fork polarity grad ...... ng domains in human cell lines
@nl
type
label
Replication fork polarity grad ...... ng domains in human cell lines
@ast
Replication fork polarity grad ...... ng domains in human cell lines
@en
Replication fork polarity grad ...... ng domains in human cell lines
@nl
prefLabel
Replication fork polarity grad ...... ng domains in human cell lines
@ast
Replication fork polarity grad ...... ng domains in human cell lines
@en
Replication fork polarity grad ...... ng domains in human cell lines
@nl
P2093
P2860
P50
P1476
Replication fork polarity grad ...... ng domains in human cell lines
@en
P2093
Antoine Baker
Antoine Leleu
Arach Goldar
Aurélien Rappailles
Benoit Moindrot
Claude Thermes
Cédric Vaillant
Guillaume Guilbaud
Yves d'Aubenton-Carafa
P2860
P304
P356
10.1371/JOURNAL.PCBI.1002443
P577
2012-04-05T00:00:00Z