Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress. - Wikidata - awgldk - TriplyDB

Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress.

Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress.

http://www.wikidata.org/entity/Q34229596

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Molecular basis of electrophilic and oxidative defense: promises and perils of Nrf2 Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice Critical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2 Resveratrol inhibits paraquat-induced oxidative stress and fibrogenic response by activating the Nrf2 pathway NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation Disruption of Nrf2 synergizes with high glucose to cause heightened myocardial oxidative stress and severe cardiomyopathy in diabetic mice Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2 Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling The chemical defensome: environmental sensing and response genes in the Strongylocentrotus purpuratus genome Role of Nrf1 in antioxidant response element-mediated gene expression and beyond Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism Redox modification of cell signaling in the cardiovascular system Regulation of Drosophila metamorphosis by xenobiotic response regulators The C-terminal domain of Nrf1 negatively regulates the full-length CNC-bZIP factor and its shorter isoform LCR-F1/Nrf1β; both are also inhibited by the small dominant-negative Nrf1γ/δ isoforms that down-regulate ARE-battery gene expression Tumor progression and the different faces of the PERK kinase The p65 isoform of Nrf1 is a dominant negative inhibitor of ARE-mediated transcription Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain. Inhibition of nuclear translocation and transacting function Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum Embryonic lethality and fetal liver apoptosis in mice lacking all three small Maf proteins Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1 Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes.Flavonoids: modulators of brain function?Long isoforms of NRF1 contribute to arsenic-induced antioxidant response in human keratinocytes Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes Nrf2 transcriptionally activates the mafG gene through an antioxidant response element Stress-activated cap'n'collar transcription factors in aging and human disease Coordinated regulation of Nrf2 and histone H3 serine 10 phosphorylation in arsenite-activated transcription of the human heme oxygenase-1 gene Regulation of Nrf2-an update Oncogene PKCε controls INrf2-Nrf2 interaction in normal and cancer cells through phosphorylation of INrf2 The transcription factor NF-E2-related factor 2 (Nrf2): a protooncogene?Th2 skewing by activation of Nrf2 in CD4(+) T cells Effects of deletion of the transcription factor Nrf2 and benzo [a]pyrene treatment on ovarian follicles and ovarian surface epithelial cells in mice Nrf2 and Nrf2-related proteins in development and developmental toxicity: Insights from studies in zebrafish (Danio rerio)Genomic and genotoxic responses to controlled weathered-oil exposures confirm and extend field studies on impacts of the Deepwater Horizon oil spill on native killifish.Mitochondrial dysfunction and reduced prostaglandin synthesis in skeletal muscle of Group VIB Ca2+-independent phospholipase A2gamma-deficient mice.Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription.Redox regulatory mechanisms in cellular stress responses.

P2860

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P2860

Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress.

http://www.wikidata.org/entity/Q34229596

description

2003 nî lūn-bûn

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2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Deficiency of the Nrf1 and Nrf ...... y and severe oxidative stress.

@ast

Deficiency of the Nrf1 and Nrf ...... y and severe oxidative stress.

@en

Deficiency of the Nrf1 and Nrf ...... y and severe oxidative stress.

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type

label

Deficiency of the Nrf1 and Nrf ...... y and severe oxidative stress.

@ast

Deficiency of the Nrf1 and Nrf ...... y and severe oxidative stress.

@en

Deficiency of the Nrf1 and Nrf ...... y and severe oxidative stress.

@nl

prefLabel

Deficiency of the Nrf1 and Nrf ...... y and severe oxidative stress.

@ast

Deficiency of the Nrf1 and Nrf ...... y and severe oxidative stress.

@en

Deficiency of the Nrf1 and Nrf ...... y and severe oxidative stress.

@nl

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P1433

Journal of Biological Chemistry

P1476

Deficiency of the Nrf1 and Nrf ...... y and severe oxidative stress.

@en

P2093

Candy Lee

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Jefferson Y Chan

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Laura Leung

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Mandy Kwong

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Stephen Hou

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P2860

Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3

Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner

Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice.

Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

Isolation of cDNA encoding the human NF-E2 protein

Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site

Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene

The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents. Role for Nrf1 in gamma-gcs(l) and gss expression in mouse fibroblasts

P304

48021-48029

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10.1074/JBC.M308439200

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P407

P433

48

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P478

278

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P577

2003-09-10T00:00:00Z

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12968018

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