SMAC mimetic (JP1201) sensitizes non-small cell lung cancers to multiple chemotherapy agents in an IAP-dependent but TNF-α-independent manner
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Small-molecule SMAC mimetics as new cancer therapeuticsPutting the pieces together: How is the mitochondrial pathway of apoptosis regulated in cancer and chemotherapy?Downregulation of Smac attenuates H2O2-induced apoptosis via endoplasmic reticulum stress in human lens epithelial cellsSmac mimetic SM-164 potentiates APO2L/TRAIL- and doxorubicin-mediated anticancer activity in human hepatocellular carcinoma cellsLCL161 increases paclitaxel-induced apoptosis by degrading cIAP1 and cIAP2 in NSCLC.Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNFα and ROS production.A potential role of X-linked inhibitor of apoptosis protein in mitochondrial membrane permeabilization and its implication in cancer therapyIntrinsic and chemo-sensitizing activity of SMAC-mimetics on high-risk childhood acute lymphoblastic leukemia.BIBF 1120 (nintedanib), a triple angiokinase inhibitor, induces hypoxia but not EMT and blocks progression of preclinical models of lung and pancreatic cancer.Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations.ZEB1 drives epithelial-to-mesenchymal transition in lung cancer.Smac mimetics induce inflammation and necrotic tumour cell death by modulating macrophage activity.Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination.A Smac mimetic augments the response of urothelial cancer cells to gemcitabine and cisplatin.Anti-cancer IAP antagonists promote bone metastasis: a cautionary tale.Differential role of RIP1 in Smac mimetic-mediated chemosensitization of neuroblastoma cells.Effect of Second mitochondria-derived activator of caspase in combination with Docetaxel on lung cancer cell A549.The innate immune response in fetal lung mesenchymal cells targets VEGFR2 expression and activity.Inhibition of Hedgehog signaling sensitizes NSCLC cells to standard therapies through modulation of EMT-regulating miRNAs.PKC activation sensitizes basal-like breast cancer cell lines to Smac mimetics.SMAC Mimetic BV6 Enables Sensitization of Resistant Tumor Cells but also Affects Cytokine-Induced Killer (CIK) Cells: A Potential Challenge for Combination Therapy.Inhibitor of Apoptosis Proteins: Promising Targets for Cancer Therapy.Sensitization of neuroblastoma for vincristine-induced apoptosis by Smac mimetic LCL161 is attended by G2 cell cycle arrest but is independent of NFκB, RIP1 and TNF-α.Interferon-γ and Smac mimetics synergize to induce apoptosis of lung cancer cells in a TNFα-independent manner.
P2860
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P2860
SMAC mimetic (JP1201) sensitizes non-small cell lung cancers to multiple chemotherapy agents in an IAP-dependent but TNF-α-independent manner
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2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
SMAC mimetic (JP1201) sensitiz ...... t but TNF-α-independent manner
@ast
SMAC mimetic (JP1201) sensitiz ...... t but TNF-α-independent manner
@en
SMAC mimetic
@nl
type
label
SMAC mimetic (JP1201) sensitiz ...... t but TNF-α-independent manner
@ast
SMAC mimetic (JP1201) sensitiz ...... t but TNF-α-independent manner
@en
SMAC mimetic
@nl
prefLabel
SMAC mimetic (JP1201) sensitiz ...... t but TNF-α-independent manner
@ast
SMAC mimetic (JP1201) sensitiz ...... t but TNF-α-independent manner
@en
SMAC mimetic
@nl
P2093
P2860
P1433
P1476
SMAC mimetic (JP1201) sensitiz ...... t but TNF-α-independent manner
@en
P2093
Adi F Gazdar
John D Minna
Luc Girard
Michael Peyton
Patrick Harran
Rachel M Greer
Rolf A Brekken
Xiaodong Wang
P2860
P304
P356
10.1158/0008-5472.CAN-10-3947
P407
P577
2011-11-02T00:00:00Z