The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development.
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CaSR stimulates secretion of Wnt5a from colonic myofibroblasts to stimulate CDX2 and sucrase-isomaltase using Ror2 on intestinal epitheliaThe role of Reg IV in colorectal cancer, as a potential therapeutic targetCDX2 expression is progressively decreased in human gastric intestinal metaplasia, dysplasia and cancerCdx2 determines the fate of postnatal intestinal endodermThe intestine-specific transcription factor Cdx2 inhibits beta-catenin/TCF transcriptional activity by disrupting the beta-catenin-TCF protein complex.Histone hypoacetylation contributes to CXCL12 downregulation in colon cancer: impact on tumor growth and cell migration.Caudal homeobox protein Cdx-2 cooperates with Wnt pathway to regulate claudin-1 expression in colon cancer cells.Transcriptional regulation of the intestinal nuclear bile acid farnesoid X receptor (FXR) by the caudal-related homeobox 2 (CDX2).Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity.Intestine-specific transcription factor Cdx2 induces E-cadherin function by enhancing the trafficking of E-cadherin to the cell membraneModulation of iron transport proteins in human colorectal carcinogenesis.CDX1 and CDX2 expression in intestinal metaplasia, dysplasia and gastric cancerLoss of CDX2 expression is associated with poor prognosis in colorectal cancer patients.CDX2 regulates multidrug resistance 1 gene expression in malignant intestinal epithelium.Modified-chitosan/siRNA nanoparticles downregulate cellular CDX2 expression and cross the gastric mucus barrier.Vitamin D receptor Cdx-2 polymorphism and premenopausal breast cancer risk in southern Pakistani patientsCDX2 as a marker for intestinal differentiation: Its utility and limitations.Functional interaction between the homeoprotein CDX1 and the transcriptional machinery containing the TATA-binding proteinThe microenvironment controls CDX2 homeobox gene expression in colorectal cancer cellsReactivation of CDX2 in Gastric Cancer as Mark for Gene Silencing MemoryThe role of Cdx genes in the mammalian gut.Cdx2 homeoprotein inhibits non-homologous end joining in colon cancer but not in leukemia cells.Overexpression of caudal-related homeobox transcription factor 2 inhibits the growth of transplanted colorectal tumors in nude mice.Ets2 regulates colonic stem cells and sensitivity to tumorigenesis.Activation of two distinct Sox9-EGFP-expressing intestinal stem cell populations during crypt regeneration after irradiation.Methylation-dependent activation of CDX1 through NF-κB: a link from inflammation to intestinal metaplasia in the human stomach.HOXB4 Gene Expression Is Regulated by CDX2 in Intestinal Epithelial Cells.Different effects of the Cdx1 and Cdx2 homeobox genes in a murine model of intestinal inflammation.Intestinal apoptotic changes linked to metabolic status in fasted and refed rats.Down-regulation of Cdx2 in colorectal carcinoma cells by the Raf-MEK-ERK 1/2 pathwayCDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancerSOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genesThe guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel diseaseThe homeodomain transcription factor Cdx1 does not behave as an oncogene in normal mouse intestine.CDX2 is an amplified lineage-survival oncogene in colorectal cancer.CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness.Noncanonical cell death programs in the nematode Caenorhabditis elegans.Prognosis of invasive intraductal papillary mucinous neoplasm depends on histological and precursor epithelial subtypes.Stress-dependent Daxx-CHIP interaction suppresses the p53 apoptotic program.
P2860
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P2860
The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development.
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The Cdx2 homeobox gene has a t ...... c role during gut development.
@ast
The Cdx2 homeobox gene has a t ...... c role during gut development.
@en
The Cdx2 homeobox gene has a t ...... c role during gut development.
@nl
type
label
The Cdx2 homeobox gene has a t ...... c role during gut development.
@ast
The Cdx2 homeobox gene has a t ...... c role during gut development.
@en
The Cdx2 homeobox gene has a t ...... c role during gut development.
@nl
prefLabel
The Cdx2 homeobox gene has a t ...... c role during gut development.
@ast
The Cdx2 homeobox gene has a t ...... c role during gut development.
@en
The Cdx2 homeobox gene has a t ...... c role during gut development.
@nl
P2093
P2860
P356
P1433
P1476
The Cdx2 homeobox gene has a t ...... ic role during gut development
@en
P2093
C Bonhomme
C Domon-Dell
K Chawengsaksophak
M Kedinger
M-P Chenard
P2860
P304
P356
10.1136/GUT.52.10.1465
P407
P577
2003-10-01T00:00:00Z