Directed evolution of Streptomyces clavuligerus deacetoxycephalosporin C synthase for enhancement of penicillin G expansion.
about
Assessing directed evolution methods for the generation of biosynthetic enzymes with potential in drug biosynthesis.Iterative combinatorial mutagenesis as an effective strategy for generation of deacetoxycephalosporin C synthase with improved activity toward penicillin G.Relevant double mutations in bioengineered Streptomyces clavuligerus deacetoxycephalosporin C synthase result in higher binding specificities which improve penicillin bioconversion.Engineering deacetoxycephalosporin C synthase as a catalyst for the bioconversion of penicillins.Modified Deacetylcephalosporin C Synthase for the Biotransformation of Semisynthetic Cephalosporins
P2860
Directed evolution of Streptomyces clavuligerus deacetoxycephalosporin C synthase for enhancement of penicillin G expansion.
description
2005 nî lūn-bûn
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2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Directed evolution of Streptom ...... ent of penicillin G expansion.
@ast
Directed evolution of Streptom ...... ent of penicillin G expansion.
@en
Directed evolution of Streptom ...... ent of penicillin G expansion.
@nl
type
label
Directed evolution of Streptom ...... ent of penicillin G expansion.
@ast
Directed evolution of Streptom ...... ent of penicillin G expansion.
@en
Directed evolution of Streptom ...... ent of penicillin G expansion.
@nl
prefLabel
Directed evolution of Streptom ...... ent of penicillin G expansion.
@ast
Directed evolution of Streptom ...... ent of penicillin G expansion.
@en
Directed evolution of Streptom ...... ent of penicillin G expansion.
@nl
P2093
P2860
P1476
Directed evolution of Streptom ...... ent of penicillin G expansion.
@en
P2093
Chan-Hui Deng
Chia-Li Wei
Jyh-Shing Hsu
Shwu-Huey Liaw
Wen-Chi Liu
Ying-Chieh Tsai
Yu-Ching Lin
Yunn-Bor Yang
P2860
P304
P356
10.1128/AEM.71.12.8873-8880.2005
P407
P577
2005-12-01T00:00:00Z