Ribozyme gene therapy: applications for molecular medicine.
about
Target-dependent on/off switch increases ribozyme fidelityAutomated design of hammerhead ribozymes and validation by targeting the PABPN1 gene transcript.Ribozymes: catalytic RNAs that cut things, make things, and do odd and useful jobsDevelopment and comparison of procedures for the selection of delta ribozyme cleavage sites within the hepatitis B virus.An animal model of PDH deficiency using AAV8-siRNA vector-mediated knockdown of pyruvate dehydrogenase E1αRNase P: variations and uses.Cutaneous gene transfer for skin and systemic diseases.Gene therapy for airway diseases: continued progress toward identifying and overcoming barriers to efficiency.Current status of gene therapy for inherited lung diseasesVariables and strategies in development of therapeutic post-transcriptional gene silencing agentsRibozyme-based gene-inactivation systems require a fine comprehension of their substrate specificities; the case of delta ribozymeGene therapy for proliferative ocular diseases.Catalytic nucleic acid enzymes for the study and development of therapies in the central nervous system: Review Article.Convergent evolution of twintron-like configurations: One is never enough.AAV vectors for RNA-based modulation of gene expression.The structure and function of catalytic RNAs.Advances in gene therapy technologies to treat retinitis pigmentosa.Mechanisms of disease: hypertrophic cardiomyopathy.Use of RNA in drug design.Computational design and experimental validation of oligonucleotide-sensing allosteric ribozymes.Validation of tissue-specific promoter-driven tumor-targeting trans-splicing ribozyme system as a multifunctional cancer gene therapy device in vivo.A new modified DNA enzyme that targets influenza virus A mRNA inhibits viral infection in cultured cells.Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities.Hammerhead ribozyme-mediated knockdown of mRNA for fibrotic growth factors: transforming growth factor-beta 1 and connective tissue growth factorA cellular high-throughput screening approach for therapeutic trans-cleaving ribozymes and RNAi against arbitrary mRNA disease targets.Cleavage of pyrene-stabilized RNA bulge loops by trans-(±)-cyclohexane-1,2-diamine.Small molecule control of pre-mRNA splicing.Specific inhibition of gene expression and transactivation functions of hepatitis B virus X protein and c-myc by small interfering RNAs.Efficient inhibition of beta-secretase gene expression in HEK293 cells by tRNAVal-driven and CTE-helicase associated hammerhead ribozymes.Addition of an extra substrate binding site and partial destabilization of stem structures in HDV ribozyme give rise to high sequence-specificity for its target RNA.The synthesis and properties of oligoribonucleotide-spermine conjugates.Targeted inhibition of human collagenase-3 (MMP-13) expression inhibits squamous cell carcinoma growth in vivo.Site-Selective RNA Splicing Nanozyme: DNAzyme and RtcB Conjugates on a Gold Nanoparticle.Soft Interactions with Model Crowders and Non-canonical Interactions with Cellular Proteins Stabilize RNA Folding.Development of an efficient cis-trans-cis ribozyme cassette to inactivate plant genes.
P2860
Q24793993-07CB98D8-7BCB-4465-A578-A84F93F4CE8DQ27325506-0E17D7FC-5AB6-4F26-ACC4-96B4350D0A82Q28680776-5EC89EE2-EBFF-4BA5-A9C4-F9F3EA149A24Q31116966-9CEC1849-E740-4023-8866-448440059A77Q34176831-A8CC3DF8-E955-43DD-AAC1-696745B0EAE7Q34462159-FAE45020-9679-4A4C-8542-CCCA641AE060Q34696240-97094685-8ED8-438A-89CF-070EE61C70B0Q34768922-EDB529C5-5C77-416D-ACC9-E0902D33BE6AQ35043830-B628DB84-1619-4858-8FAE-11A5F07FF3A7Q35110219-22C50E10-B79B-4A63-891B-A11EBCE54A59Q35552101-7E506D47-3DEA-4511-AE41-8CC9BE9E6098Q35842653-2D129E9B-3DEE-47B2-952F-91F72A5D9DA3Q36391856-30AF4A72-A71B-4FD2-8184-4D1B6167A649Q36791493-18ED2736-5D91-4DDD-A47D-207C7C168393Q37140645-BD44D69D-5CF4-46CF-8168-0C8603728F22Q37417135-5FCE823C-A2E3-4E2C-8595-FCA9F8D0F179Q37427526-91968636-D285-4443-B0D4-B8BF3AB1B788Q37949516-ADEE973D-AA82-47DF-A1B3-85A52DFB7A1CQ38089160-56A61576-C5CC-4D7F-8D60-7DEFD5D141E8Q38319596-75A068C5-3237-43FF-8E58-8455C184D0E5Q39945361-BB0FB987-2A0F-4F5F-BD65-7C1C3C3FC179Q40585082-F956322D-EC3D-4631-9EB4-BD5794C93134Q40773184-FAB264A2-E69E-470A-BDBE-94083BB9ED49Q40894947-CC71DE1C-8A6A-418A-B68C-346218A65A91Q41641558-1E8A2AC0-25E5-4442-AFE0-9708ADBB8B95Q42174423-E09D3BBF-7413-4899-A11E-DC56E7E580ACQ42283312-45C7F0DB-B74A-4B74-BFA9-A111112FC88EQ42620818-4C835339-DDAB-4153-BEBD-A62CEA6F4042Q44597512-A8104094-50A9-4008-AA52-D82E6C23252DQ44773703-B751F47E-B16C-43E4-A761-9E8D34246CAEQ44978971-149455D3-8B87-47FB-809C-472D8C5A3B6FQ45234886-29F60105-0A27-4C7C-9CB2-D82363AB4FB7Q47332201-158DFBFE-FCC9-4DB3-BA63-3C1467BDA931Q47413172-DC1B4A7D-F877-4E7E-9D91-0CA7EAAAB97AQ51099643-89687099-3331-4720-BE86-D0C5389FE522
P2860
Ribozyme gene therapy: applications for molecular medicine.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Ribozyme gene therapy: applications for molecular medicine.
@ast
Ribozyme gene therapy: applications for molecular medicine.
@en
Ribozyme gene therapy: applications for molecular medicine.
@nl
type
label
Ribozyme gene therapy: applications for molecular medicine.
@ast
Ribozyme gene therapy: applications for molecular medicine.
@en
Ribozyme gene therapy: applications for molecular medicine.
@nl
prefLabel
Ribozyme gene therapy: applications for molecular medicine.
@ast
Ribozyme gene therapy: applications for molecular medicine.
@en
Ribozyme gene therapy: applications for molecular medicine.
@nl
P1476
Ribozyme gene therapy: applications for molecular medicine.
@en
P2093
Hauswirth WW
P304
P356
10.1016/S1471-4914(01)01965-7
P577
2001-05-01T00:00:00Z