Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor
about
Independent movement of the voltage sensors in KV2.1/KV6.4 heterotetramersExternal pH modulates EAG superfamily K+ channels through EAG-specific acidic residues in the voltage sensorComputational processing of optical measurements of neuronal and synaptic activity in networks.Use of voltage clamp fluorimetry in understanding potassium channel gating: a review of Shaker fluorescence data.Fluorescence-tracking of activation gating in human ERG channels reveals rapid S4 movement and slow pore openingTransfer of ion binding site from ether-a-go-go to Shaker: Mg2+ binds to resting state to modulate channel openingExcitation-contraction coupling from the 1950s into the new millennium.Relative motion of transmembrane segments S0 and S4 during voltage sensor activation in the human BK(Ca) channelIntracellular regions of the Eag potassium channel play a critical role in generation of voltage-dependent currents.Voltage-dependent conformational changes in human Ca(2+)- and voltage-activated K(+) channel, revealed by voltage-clamp fluorometry.R1 in the Shaker S4 occupies the gating charge transfer center in the resting stateDynamics of internal pore opening in K(V) channels probed by a fluorescent unnatural amino acid.Divalent cations slow activation of EAG family K+ channels through direct binding to S4Conformational changes associated with proton-dependent gating of ASIC1a.Components of gating charge movement and S4 voltage-sensor exposure during activation of hERG channels.Voltage-dependent conformational changes of KVAP S4 segment in bacterial membrane environment.Differences between ion binding to eag and HERG voltage sensors contribute to differential regulation of activation and deactivation gating.Modulation of HERG gating by a charge cluster in the N-terminal proximal domain.Voltage clamp fluorimetry reveals a novel outer pore instability in a mammalian voltage-gated potassium channel.Intracellular linkers are involved in Mg2+-dependent modulation of the Eag potassium channel.The intrinsically liganded cyclic nucleotide-binding homology domain promotes KCNH channel activation.
P2860
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P2860
Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Optical detection of rate-dete ...... o-go K+ channel voltage sensor
@ast
Optical detection of rate-dete ...... o-go K+ channel voltage sensor
@en
Optical detection of rate-dete ...... o-go K+ channel voltage sensor
@nl
type
label
Optical detection of rate-dete ...... o-go K+ channel voltage sensor
@ast
Optical detection of rate-dete ...... o-go K+ channel voltage sensor
@en
Optical detection of rate-dete ...... o-go K+ channel voltage sensor
@nl
prefLabel
Optical detection of rate-dete ...... o-go K+ channel voltage sensor
@ast
Optical detection of rate-dete ...... o-go K+ channel voltage sensor
@en
Optical detection of rate-dete ...... o-go K+ channel voltage sensor
@nl
P2093
P2860
P356
P1476
Optical detection of rate-dete ...... o-go K+ channel voltage sensor
@en
P2093
Diane M Papazian
Francisco Bezanilla
John P A Bannister
P2860
P304
18718-18723
P356
10.1073/PNAS.0505766102
P407
P50
P577
2005-12-09T00:00:00Z