Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism - Wikidata - awgldk - TriplyDB

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

http://www.wikidata.org/entity/Q34235866

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Hepatitis B virus-X protein upregulates the expression of p21waf1/cip1 and prolongs G1-->S transition via a p53-independent pathway in human hepatoma cells Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C Prognostic significance of BMP and activin membrane-bound inhibitor in colorectal cancer Basic helix-loop-helix transcription factor epicardin/capsulin/Pod-1 suppresses differentiation by negative regulation of transcription PPM1A dephosphorylates RanBP3 to enable efficient nuclear export of Smad2 and Smad3 E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells S100C/A11 is a key mediator of Ca(2+)-induced growth inhibition of human epidermal keratinocytes Loss of p12CDK2-AP1 expression in human oral squamous cell carcinoma with disrupted transforming growth factor-beta-Smad signaling pathway Smads bind directly to the Jun family of AP-1 transcription factors Transforming growth factor-beta and breast cancer: Cell cycle arrest by transforming growth factor-beta and its disruption in cancer A molecular 'signature' of primary breast cancer cultures; patterns resembling tumor tissue Transforming growth factor beta-1 decreases the yield of the second meiotic division of rat pachytene spermatocytes in vitro Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their Crosstalks TGF-β - an excellent servant but a bad master Altered expression of cell cycle and apoptotic proteins in chronic hepatitis C virus infection Dysregulation of TGFβ1 Activity in Cancer and Its Influence on the Quality of Anti-Tumor Immunity Switching Roles of TGF-β in Cancer Development: Implications for Therapeutic Target and Biomarker Studies Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review)TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-β signaling Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor beta inhibitor Smad7 via the ETS protein ER81 Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor The ETS family transcription factor ELK-1 regulates induction of the cell cycle-regulatory gene p21(Waf1/Cip1) and the BAX gene in sodium arsenite-exposed human keratinocyte HaCaT cells Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation The anaphase-promoting complex coordinates initiation of lens differentiation Premature senescence and increased TGFβ signaling in the absence of Tgif1.The ink4a/arf tumor suppressors cooperate with p21cip1/waf in the processes of mouse epidermal differentiation, senescence, and carcinogenesis Tbx1 regulates progenitor cell proliferation in the dental epithelium by modulating Pitx2 activation of p21 Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication Engulfment protein GULP is regulator of transforming growth factor-β response in ovarian cells.Cell cycle related proteins in hyperplasia of usual type in breast specimens of patients with and without breast cancer.Association between endogenous gene expression and growth regulation induced by TGF-beta1 in human gastric cancer cells TGFB1 and TGFBR1 polymorphisms and breast cancer risk in the Nurses' Health Study.Reciprocal regulation of p63 by C/EBP delta in human keratinocytes.

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P2860

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

http://www.wikidata.org/entity/Q34235866

description

1995 nî lūn-bûn

@nan

1995 թուականի Յունիսին հրատարակուած գիտական յօդուած

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1995 թվականի հունիսին հրատարակված գիտական հոդված

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1995年の論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年论文

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name

Transforming growth factor bet ...... gh a p53-independent mechanism

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Transforming growth factor bet ...... gh a p53-independent mechanism

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Transforming growth factor bet ...... gh a p53-independent mechanism

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Transforming growth factor bet ...... gh a p53-independent mechanism

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Transforming growth factor bet ...... gh a p53-independent mechanism

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Transforming growth factor bet ...... gh a p53-independent mechanism

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Transforming growth factor bet ...... gh a p53-independent mechanism

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Transforming growth factor bet ...... gh a p53-independent mechanism

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Transforming growth factor bet ...... gh a p53-independent mechanism

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Transforming growth factor bet ...... gh a p53-independent mechanism

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D J Howe

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J F Panus

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X F Wang

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Y Li

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P2860

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

TGF beta signals through a heteromeric protein kinase receptor complex

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

WAF1, a potential mediator of p53 tumor suppression

D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

p21 is a universal inhibitor of cyclin kinases

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