The role of cofactors in prion propagation and infectivity
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Techniques to elucidate the conformation of prionsIntraperitoneal Infection of Wild-Type Mice with Synthetically Generated Mammalian PrionSilencing prion protein in MDA-MB-435 breast cancer cells leads to pleiotropic cellular responses to cytotoxic stimuliIntroducing a rigid loop structure from deer into mouse prion protein increases its propensity for misfolding in vitroCritical significance of the region between Helix 1 and 2 for efficient dominant-negative inhibition by conversion-incompetent prion proteinSelective propagation of mouse-passaged scrapie prions with long incubation period from a mixed prion population using GT1-7 cells.Comparison of 2 synthetically generated recombinant prions.Involvement of endogenous retroviruses in prion diseases.Ubiquitin ligase gp78 targets unglycosylated prion protein PrP for ubiquitylation and degradation.Interaction of prion protein with acetylcholinesterase: potential pathobiological implications in prion diseases.Contrasting Effects of Two Lipid Cofactors of Prion Replication on the Conformation of the Prion ProteinModulation of Glycosaminoglycans Affects PrPSc Metabolism but Does Not Block PrPSc Uptake.Pre-amyloid oligomers of the proteotoxic RepA-WH1 prionoid assemble at the bacterial nucleoidSecondary-structure prediction revisited: Theoretical β-sheet propensity and coil propensity represent structures of amyloids and aid in elucidating phenomena involved in interspecies transmission of prions.Influence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2Getting to the core of prion superstructural variability.De novo generation of infectious prions with bacterially expressed recombinant prion protein.Prion protein misfolding, strains, and neurotoxicity: an update from studies on Mammalian prions.Divergent prion strain evolution driven by PrPC expression level in transgenic mice.Role of lipid in forming an infectious prion?Treatment with a non-toxic, self-replicating anti-prion delays or prevents prion disease in vivo.Modulation of amyloid assembly by glycosaminoglycans: from mechanism to biological significance.Heparan Sulfate and Heparin Promote Faithful Prion Replication in Vitro by Binding to Normal and Abnormal Prion Proteins in Protein Misfolding Cyclic Amplification.Pathological implications of nucleic acid interactions with proteins associated with neurodegenerative diseasesSelf-propagating, protease-resistant, recombinant prion protein conformers with or without in vivo pathogenicity.Multiple affinity purification of a baculovirus-derived recombinant prion protein with in vitro ability to convert to its pathogenic form.How do PrPSc Prions Spread between Host Species, and within Hosts?Direct observation of murine prion protein replication in vitro
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P2860
The role of cofactors in prion propagation and infectivity
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2012 nî lūn-bûn
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2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2012 թվականի ապրիլին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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The role of cofactors in prion propagation and infectivity
@ast
The role of cofactors in prion propagation and infectivity
@en
The role of cofactors in prion propagation and infectivity
@nl
type
label
The role of cofactors in prion propagation and infectivity
@ast
The role of cofactors in prion propagation and infectivity
@en
The role of cofactors in prion propagation and infectivity
@nl
prefLabel
The role of cofactors in prion propagation and infectivity
@ast
The role of cofactors in prion propagation and infectivity
@en
The role of cofactors in prion propagation and infectivity
@nl
P2860
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The role of cofactors in prion propagation and infectivity
@en
P2093
P2860
P304
P356
10.1371/JOURNAL.PPAT.1002589
P5008
P577
2012-04-12T00:00:00Z