Negative modulation of GABAA α5 receptors by RO4938581 attenuates discrete sub-chronic and early postnatal phencyclidine (PCP)-induced cognitive deficits in rats.
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Pathophysiological power of improper tonic GABA(A) conductances in mature and immature models.Negative modulation of α₅ GABAA receptors in rats may partially prevent memory impairment induced by MK-801, but not amphetamine- or MK-801-elicited hyperlocomotionFrom pan-reactive KV7 channel opener to subtype selective opener/inhibitor by addition of a methyl groupBehavioral effects of the benzodiazepine-positive allosteric modulator SH-053-2'F-S-CH₃ in an immune-mediated neurodevelopmental disruption model.GABAA receptor subtypes: Therapeutic potential in Down syndrome, affective disorders, schizophrenia, and autism.The role of dopamine in schizophrenia from a neurobiological and evolutionary perspective: old fashioned, but still in vogue.Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the α5 subunit.A Multifaceted GABAA Receptor Modulator: Functional Properties and Mechanism of Action of the Sedative-Hypnotic and Recreational Drug Methaqualone (Quaalude)The Novel, Nicotinic Alpha7 Receptor Partial Agonist, BMS-933043, Improves Cognition and Sensory Processing in Preclinical Models of Schizophrenia.Enhancement of postsynaptic GABAA and extrasynaptic NMDA receptor-mediated responses in the barrel cortex of Mecp2-null mice.Neural oscillations during non-rapid eye movement sleep as biomarkers of circuit dysfunction in schizophrenia.The subchronic phencyclidine rat model: relevance for the assessment of novel therapeutics for cognitive impairment associated with schizophrenia.Postnatal Phencyclidine (PCP) as a Neurodevelopmental Animal Model of Schizophrenia Pathophysiology and Symptomatology: A Review.Dopamine dysregulation in the prefrontal cortex relates to cognitive deficits in the sub-chronic PCP-model for schizophrenia: A preliminary investigation.MAM-E17 rat model impairments on a novel continuous performance task: effects of potential cognitive enhancing drugs.GABAA receptor subunit deregulation in the hippocampus of human foetuses with Down syndrome.Short-Term Exposure to Enriched Environment in Adult Rats Restores MK-801-Induced Cognitive Deficits and GABAergic Interneuron Immunoreactivity Loss.Neonatal phencyclidine administration and post-weaning social isolation as a dual-hit model of 'schizophrenia-like' behaviour in the rat.In vitro and in vivo characterisation of Lu AF64280, a novel, brain penetrant phosphodiesterase (PDE) 2A inhibitor: potential relevance to cognitive deficits in schizophrenia.Vortioxetine Treatment Reverses Subchronic PCP Treatment-Induced Cognitive Impairments: A Potential Role for Serotonin Receptor-Mediated Regulation of GABA Neurotransmission.GABAergic inhibitory neurons as therapeutic targets for cognitive impairment in schizophrenia.
P2860
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P2860
Negative modulation of GABAA α5 receptors by RO4938581 attenuates discrete sub-chronic and early postnatal phencyclidine (PCP)-induced cognitive deficits in rats.
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Negative modulation of GABAA α ...... ed cognitive deficits in rats.
@ast
Negative modulation of GABAA α ...... ed cognitive deficits in rats.
@en
Negative modulation of GABAA α ...... early postnatal phencyclidine
@nl
type
label
Negative modulation of GABAA α ...... ed cognitive deficits in rats.
@ast
Negative modulation of GABAA α ...... ed cognitive deficits in rats.
@en
Negative modulation of GABAA α ...... early postnatal phencyclidine
@nl
prefLabel
Negative modulation of GABAA α ...... ed cognitive deficits in rats.
@ast
Negative modulation of GABAA α ...... ed cognitive deficits in rats.
@en
Negative modulation of GABAA α ...... early postnatal phencyclidine
@nl
P2093
P2860
P1433
P1476
Negative modulation of GABAA α ...... ed cognitive deficits in rats.
@en
P2093
Anne Techau Bruun
Christoffer Bundgaard
Garrick P Smith
Inge E M de Jong
John P Redrobe
Kristen Frederiksen
Lisbeth Elster
Michael Didriksen
Peter H Larsen
P2860
P2888
P304
P356
10.1007/S00213-011-2593-9
P577
2011-11-29T00:00:00Z
P6179
1002156307