Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway.
about
Skeletal muscle PGC-1α controls whole-body lactate homeostasis through estrogen-related receptor α-dependent activation of LDH B and repression of LDH AComplex Coordination of Cell Plasticity by a PGC-1α-controlled Transcriptional Network in Skeletal MuscleCaloric restriction and exercise "mimetics'': Ready for prime time?Impact of oxidative stress on exercising skeletal muscleThe diverse role of the PPARγ coactivator 1 family of transcriptional coactivators in cancerRosiglitazone-induced mitochondrial biogenesis in white adipose tissue is independent of peroxisome proliferator-activated receptor γ coactivator-1αCompromised mitochondrial fatty acid synthesis in transgenic mice results in defective protein lipoylation and energy disequilibriumArctigenin efficiently enhanced sedentary mice treadmill enduranceSuppression of 5'-nucleotidase enzymes promotes AMP-activated protein kinase (AMPK) phosphorylation and metabolism in human and mouse skeletal muscleEffects of Testosterone and Evoked Resistance Exercise after Spinal Cord Injury (TEREX-SCI): study protocol for a randomised controlled trialRole of Nuclear Receptors in Exercise-Induced Muscle Adaptations.PGC-1α and exercise in the control of body weight.Parkin in the regulation of fat uptake and mitochondrial biology: emerging links in the pathophysiology of Parkinson's disease.PGC-1α induces mitochondrial and myokine transcriptional programs and lipid droplet and glycogen accumulation in cultured human skeletal muscle cells.Transcriptome analysis of post-hatch breast muscle in legacy and modern broiler chickens reveals enrichment of several regulators of myogenic growthThe single nucleotide polymorphism Gly482Ser in the PGC-1α gene impairs exercise-induced slow-twitch muscle fibre transformation in humansMultiparity leads to obesity and inflammation in mothers and obesity in male offspring.Metabolomic Analysis of the Skeletal Muscle of Mice Overexpressing PGC-1αMolecular signatures of amyotrophic lateral sclerosis disease progression in hind and forelimb muscles of an SOD1(G93A) mouse modelThe coactivator PGC-1α regulates skeletal muscle oxidative metabolism independently of the nuclear receptor PPARβ/δ in sedentary mice fed a regular chow diet.PGC-1α improves glucose homeostasis in skeletal muscle in an activity-dependent manner.A role for adipose tissue de novo lipogenesis in glucose homeostasis during catch-up growth: a Randle cycle favoring fat storagePPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans.Exercise Increases and Browns Muscle Lipid in High-Fat Diet-Fed Mice.miR-34a(-/-) mice are susceptible to diet-induced obesity.Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation.Lipid metabolism in skeletal muscle: generation of adaptive and maladaptive intracellular signals for cellular function.Molecular mechanisms of muscle plasticity with exercise.Role of stearoyl-CoA desaturase-1 in skeletal muscle function and metabolism.Functional crosstalk of PGC-1 coactivators and inflammation in skeletal muscle pathophysiology.The many roles of PGC-1α in muscle--recent developmentsPGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis.Intracellular Insulin and Impaired Autophagy in a Zebrafish model and a Cell Model of Type 2 diabetes.Muscle-specific activation of Ca(2+)/calmodulin-dependent protein kinase IV increases whole-body insulin action in mice.Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha coordinates sphingolipid metabolism, lipid raft composition and myelin protein synthesis.Rescue of dystrophic skeletal muscle by PGC-1α involves restored expression of dystrophin-associated protein complex components and satellite cell signaling.The Implication of PGC-1α on Fatty Acid Transport across Plasma and Mitochondrial Membranes in the Insulin Sensitive Tissues.Normal human adipose tissue functions and differentiation in patients with biallelic LPIN1 inactivating mutations.Telomerase reverse transcriptase (TERT) - enhancer of zeste homolog 2 (EZH2) network regulates lipid metabolism and DNA damage responses in glioblastoma.High-intensity interval training and calorie restriction promote remodeling of glucose and lipid metabolism in diet-induced obesity.
P2860
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P2860
Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Peroxisome proliferator-activa ...... the pentose phosphate pathway.
@ast
Peroxisome proliferator-activa ...... the pentose phosphate pathway.
@en
Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha}
@nl
type
label
Peroxisome proliferator-activa ...... the pentose phosphate pathway.
@ast
Peroxisome proliferator-activa ...... the pentose phosphate pathway.
@en
Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha}
@nl
prefLabel
Peroxisome proliferator-activa ...... the pentose phosphate pathway.
@ast
Peroxisome proliferator-activa ...... the pentose phosphate pathway.
@en
Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha}
@nl
P2093
P2860
P356
P1476
Peroxisome proliferator-activa ...... the pentose phosphate pathway
@en
P2093
Gesa Santos
Hans Hoppeler
Oliver Baum
Serge Summermatter
P2860
P304
32793-32800
P356
10.1074/JBC.M110.145995
P407
P577
2010-08-17T00:00:00Z