Dominant negative mutations in the Wilms tumour (WT1) gene cause Denys-Drash syndrome--proof that a tumour-suppressor gene plays a crucial role in normal genitourinary development.

Dominant negative mutations in the Wilms tumour (WT1) gene cause Denys-Drash syndrome--proof that a tumour-suppressor gene plays a crucial role in normal genitourinary development.

Item
http://www.wikidata.org/entity/Q34240417
The molecular basis of genetic dominanceThe new dysmorphology: application of insights from basic developmental biology to the understanding of human birth defects.Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.Colocalization of WT1 and cell proliferation reveals conserved mechanisms in temperature-dependent sex determination.Sex determination: lessons from families and embryos.Mutations in MAP3K1 cause 46,XY disorders of sex development and implicate a common signal transduction pathway in human testis determinationIdentifying genes for male sex determination in humans.Sex, genes, and heat: triggers of diversity.Microdissecting the genetic events in nephrogenic rests and Wilms' tumor developmentCorrect dosage of Fog2 and Gata4 transcription factors is critical for fetal testis development in mice.Identification of connective tissue growth factor as a target of WT1 transcriptional regulation.Molecular genetic analysis of clear cell adenocarcinomas of the vagina and cervix associated and unassociated with diethylstilbestrol exposure in utero.The expanding phenotypic spectra of kidney diseases: insights from genetic studies.WT1-interacting protein and ZO-1 translocate into podocyte nuclei after puromycin aminonucleoside treatment.Distinct epigenomic patterns are associated with haploinsufficiency and predict risk genes of developmental disorders.
P2860

Dominant negative mutations in the Wilms tumour (WT1) gene cause Denys-Drash syndrome--proof that a tumour-suppressor gene plays a crucial role in normal genitourinary development.

Item
http://www.wikidata.org/entity/Q34240417
description
1992 nî lūn-bûn
@nan
1992 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Dominant negative mutations in ...... mal genitourinary development.
@ast
Dominant negative mutations in ...... mal genitourinary development.
@en
Dominant negative mutations in the Wilms tumour
@nl
type
label
Dominant negative mutations in ...... mal genitourinary development.
@ast
Dominant negative mutations in ...... mal genitourinary development.
@en
Dominant negative mutations in the Wilms tumour
@nl
prefLabel
Dominant negative mutations in ...... mal genitourinary development.
@ast
Dominant negative mutations in ...... mal genitourinary development.
@en
Dominant negative mutations in the Wilms tumour
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Dominant negative mutations in ...... mal genitourinary development.
@en
P2093
P304
P31
P356
P433
P478
P577
P698