Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels.
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From proprotein convertase subtilisin/kexin type 9 to its inhibition: state-of-the-art and clinical implicationsProprotein convertase subtilisin/kexin type 9: from the discovery to the development of new therapies for cardiovascular diseasesPhysiological and therapeutic regulation of PCSK9 activity in cardiovascular disease.PCSK9 and Atherosclerosis - Lipids and Beyond.Proprotein convertase subtilisin/kexin type 9 (PCSK9) in lipid metabolism, atherosclerosis and ischemic stroke.Local effects of human PCSK9 on the atherosclerotic lesion.Effects of LDL Receptor Modulation on Lymphatic FunctionBiology of proprotein convertase subtilisin kexin 9: beyond low-density lipoprotein cholesterol lowering.Proprotein convertase subtilisin/kexin type 9 expression is transiently up-regulated in the acute period of myocardial infarction in rat.Hemodynamic shear stress via ROS modulates PCSK9 expression in human vascular endothelial and smooth muscle cells and along the mouse aorta.IDOL N342S Variant, Atherosclerosis Progression and Cardiovascular Disorders in the Italian General Population.PCSK9 inhibition fails to alter hepatic LDLR, circulating cholesterol, and atherosclerosis in the absence of ApoE.Circulating Levels of Proprotein Convertase Subtilisin/Kexin Type 9 and Arterial Stiffness in a Large Population Sample: Data From the Brisighella Heart Study.Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Its Inhibitors: a Review of Physiology, Biology, and Clinical Data.Nature and nurture in atherosclerosis: The roles of acylcarnitine and cell membrane-fatty acid intermediates.Suppressor of Cytokine Signaling-3 (SOCS-3) Induces Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Expression in Hepatic HepG2 Cell Line.Effect of monoclonal antibodies to PCSK9 on high-sensitivity C-reactive protein levels: a meta-analysis of 16 randomized controlled treatment armsPlasma Levels of Proprotein Convertase Subtilisin/Kexin Type 9 Are Elevated in Patients With Peripheral Artery Disease and Associated With Metabolic Disorders and Dysfunction in Circulating Progenitor Cells.Correlation between serum levels of proprotein convertase subtilisin/kexin type 9 (PCSK9) and atherogenic lipoproteins in patients with coronary artery diseaseEpidermal growth factor receptor plays a role in the regulation of liver and plasma lipid levels in adult male micePCSK9 targets important for lipid metabolismInhibition of pro-protein convertase subtilisin kexin 9 [corrected] (PCSK-9) as a treatment for hyperlipidaemia.Anti-PCSK9 therapies for the treatment of hypercholesterolemia.PCSK9 Inhibitors: potential in cardiovascular therapeutics.Proprotein convertases subtilisin/kexin type 9, an enzyme turned escort protein: hepatic and extra hepatic functions.Proprotein convertase subtilisin/kexin 9 inhibitors: an emerging lipid-lowering therapy?Recent advances in the understanding and care of familial hypercholesterolaemia: significance of the biology and therapeutic regulation of proprotein convertase subtilisin/kexin type 9.Effect of statin therapy on plasma proprotein convertase subtilisin kexin 9 (PCSK9) concentrations: a systematic review and meta-analysis of clinical trials.PCSK9 in context: A contemporary review of an important biological target for the prevention and treatment of atherosclerotic cardiovascular disease.Effect of E670G Polymorphism in PCSK9 Gene on the Risk and Severity of Coronary Heart Disease and Ischemic Stroke in a Tunisian Cohort.Cross-talk between LOX-1 and PCSK9 in vascular tissues.High circulating proprotein convertase subtilisin/Kexin type 9 concentration associates with cardiovascular risk: A meta-analysis of cohort studies.Proprotein Convertase Subtilisin/Kexin 9 Levels in Relation to Systemic Immune Activation and Subclinical Coronary Plaque in HIV.PCSK9 induces a pro-inflammatory response in macrophages.Praluent (Alirocumab)-Induced Renal Injury.Lipid Target in Very High-Risk Cardiovascular Patients: Lesson from PCSK9 Monoclonal Antibodies.Serum PCSK9 is modified by interleukin-6 receptor antagonism in patients with hypercholesterolaemia following non-ST-elevation myocardial infarction
P2860
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P2860
Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels.
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Proprotein convertase subtilis ...... duces macrophages LDLR levels.
@ast
Proprotein convertase subtilis ...... duces macrophages LDLR levels.
@en
Proprotein convertase subtilisin kexin type 9
@nl
type
label
Proprotein convertase subtilis ...... duces macrophages LDLR levels.
@ast
Proprotein convertase subtilis ...... duces macrophages LDLR levels.
@en
Proprotein convertase subtilisin kexin type 9
@nl
prefLabel
Proprotein convertase subtilis ...... duces macrophages LDLR levels.
@ast
Proprotein convertase subtilis ...... duces macrophages LDLR levels.
@en
Proprotein convertase subtilisin kexin type 9
@nl
P2093
P1433
P1476
Proprotein convertase subtilis ...... duces macrophages LDLR levels.
@en
P2093
Alberico Luigi Catapano
Alberto Corsini
Andrea Mezzetti
Angela Pirillo
Francesco Cipollone
Gianpaolo Tibolla
Nicola Ferri
Stefano Pacia
P304
P356
10.1016/J.ATHEROSCLEROSIS.2011.11.026
P577
2011-11-25T00:00:00Z