Virtual screening using a conformationally flexible target protein: models for ligand binding to p38α MAPK.
about
Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discoveryDesign, Synthesis, and Biological Evaluation of Tetra-Substituted Thiophenes as Inhibitors of p38α MAPK.Anti-Inflammatory Effects and Joint Protection in Collagen-Induced Arthritis after Treatment with IQ-1S, a Selective c-Jun N-Terminal Kinase Inhibitor.p38α MAPK and Type I Inhibitors: Binding Site Analysis and Use of Target Ensembles in Virtual Screening.CrossDocker: a tool for performing cross-docking using Autodock Vina.Accurate calculation of mutational effects on the thermodynamics of inhibitor binding to p38α MAP kinase: a combined computational and experimental studySampling of conformational ensemble for virtual screening using molecular dynamics simulations and normal mode analysis.An Anti-Cancer Drug Candidate OSI-027 and its Analog as Inhibitors of mTOR: Computational Insights Into the Inhibitory Mechanisms.Integrating targeted gene expression and a skin model system to identify functional inhibitors of the UV activated p38 MAP kinase.
P2860
Q27684410-D168EEEE-D4C8-4E5C-99BD-AB1BFE9408EDQ35236755-48DCEE3C-4CE2-45B1-A75C-232BA3814BDFQ35600218-93C4055E-4602-411C-8319-3FEF3CE9AA45Q35762844-B455580D-87B5-42D6-8DDF-CB86479DD7B0Q36139212-FC64F84D-02AD-4A39-ABB0-07F10D97D76EQ37063817-EA715E6E-77E4-4EF6-8A05-6BE615C2F828Q38939477-5BD8C0EE-4320-40B4-A9FA-5B60425A11EFQ48185476-4DAB352B-9EED-4429-965F-09D98976BD9BQ51769536-A9DB65F8-4683-491B-B194-82396E345BD8
P2860
Virtual screening using a conformationally flexible target protein: models for ligand binding to p38α MAPK.
description
2012 nî lūn-bûn
@nan
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Virtual screening using a conf ...... r ligand binding to p38α MAPK.
@ast
Virtual screening using a conf ...... r ligand binding to p38α MAPK.
@en
Virtual screening using a conf ...... r ligand binding to p38α MAPK.
@nl
type
label
Virtual screening using a conf ...... r ligand binding to p38α MAPK.
@ast
Virtual screening using a conf ...... r ligand binding to p38α MAPK.
@en
Virtual screening using a conf ...... r ligand binding to p38α MAPK.
@nl
prefLabel
Virtual screening using a conf ...... r ligand binding to p38α MAPK.
@ast
Virtual screening using a conf ...... r ligand binding to p38α MAPK.
@en
Virtual screening using a conf ...... r ligand binding to p38α MAPK.
@nl
P2093
P2860
P1476
Virtual screening using a conf ...... r ligand binding to p38α MAPK.
@en
P2093
David K Chalmers
Jamie S Simpson
Natalie B Vinh
Peter J Scammells
P2860
P2888
P304
P356
10.1007/S10822-012-9569-7
P577
2012-04-20T00:00:00Z