Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia. - Wikidata - awgldk - TriplyDB

Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia.

Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia.

http://www.wikidata.org/entity/Q34246990

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Mitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic intervention Neurological phenotypes for Down syndrome across the life span Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease Redox proteomics analysis to decipher the neurobiology of Alzheimer-like neurodegeneration: overlaps in Down's syndrome and Alzheimer's disease brain.Oxidative stress and mitochondrial dysfunction in Alzheimer's disease.Biology and genetics of prions causing neurodegeneration Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease.Mitochondrial DNA sequence associations with dementia and amyloid-β in elderly African Americans Mitochondrial DNA sequence variation associated with dementia and cognitive function in the elderly.A mitochondrial etiology of Alzheimer and Parkinson disease Chromosome 21-derived hsa-miR-155-5p regulates mitochondrial biogenesis by targeting Mitochondrial Transcription Factor A (TFAM).Mitochondria, Amyloid β, and Alzheimer's Disease Contribution of non-reference alleles in mtDNA of Alzheimer's disease patients Analysis of mtDNA, miR-155 and BACH1 expression in hearts from donors with and without Down syndrome.Defective mitochondrial function in vivo in skeletal muscle in adults with Down's syndrome: a 31P-MRS study.Population genetics of the cytoplasm and the units of selection on mitochondrial DNA in Drosophila melanogaster Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: implications for early intervention and therapeutics.Bioenergetic origins of complexity and disease.Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics mtDNA lineage analysis of mouse L-cell lines reveals the accumulation of multiple mtDNA mutants and intermolecular recombination.Mitochondria as a therapeutic target for aging and neurodegenerative diseases.New insights in the amyloid-Beta interaction with mitochondria Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease.High throughput gene complementation screening permits identification of a mammalian mitochondrial protein synthesis (ρ(-)) mutant.Oxidative Stress and Mitochondrial Dysfunction in Down's Syndrome: Relevance to Aging and Dementia Role and treatment of mitochondrial DNA-related mitochondrial dysfunction in sporadic neurodegenerative diseases.Aging and down syndrome Antioxidants in Down syndrome.Tissue-specific implications of mitochondrial alterations in aging.A mitochondrial bioenergetic etiology of disease.Does mitochondrial DNA play a role in Parkinson's disease? A review of cybrid and other supportive evidence.Simultaneous quantification of mitochondrial DNA copy number and deletion ratio: a multiplex real-time PCR assay.Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology.Transient systemic mtDNA damage leads to muscle wasting by reducing the satellite cell pool Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease.Promise and Pitfalls of Mitochondrial Replacement for Prevention and Cure of Heritable Neurodegenerative Diseases Caused by Deleterious Mutations in Mitochondrial DNA Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline.The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives.Multiple faces of dynamin-related protein 1 and its role in Alzheimer's disease pathogenesis Cognitive impairment, genomic instability and trace elements.

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Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia.

http://www.wikidata.org/entity/Q34246990

description

2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年学术文章

@wuu

2010年学术文章

@zh-cn

2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

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2010年學術文章

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name

Systemic mitochondrial dysfunc ...... se and down syndrome dementia.

@ast

Systemic mitochondrial dysfunc ...... se and down syndrome dementia.

@en

Systemic mitochondrial dysfunc ...... se and down syndrome dementia.

@nl

type

label

Systemic mitochondrial dysfunc ...... se and down syndrome dementia.

@ast

Systemic mitochondrial dysfunc ...... se and down syndrome dementia.

@en

Systemic mitochondrial dysfunc ...... se and down syndrome dementia.

@nl

prefLabel

Systemic mitochondrial dysfunc ...... se and down syndrome dementia.

@ast

Systemic mitochondrial dysfunc ...... se and down syndrome dementia.

@en

Systemic mitochondrial dysfunc ...... se and down syndrome dementia.

@nl

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JAD-2010-100351

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Journal of Alzheimer's Disease

P1476

Systemic mitochondrial dysfunc ...... se and down syndrome dementia.

@en

P2093

Carl W Cotman

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Douglas C Wallace

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Elizabeth Head

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Eric Doran

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Goar Melkonian

http://www.w3.org/2001/XMLSchema#string

Ira T Lott

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Joanne Wyrembak

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Olga Derbereva

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Pinar E Coskun

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P2860

Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease

Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease

Alpha- and beta-secretase activity as a function of age and beta-amyloid in Down syndrome and normal brain

Alzheimer disease and Down syndrome: factors in pathogenesis

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

cDNA sequence of a human skeletal muscle ADP/ATP translocator: lack of a leader peptide, divergence from a fibroblast translocator cDNA, and coevolution with mitochondrial DNA genes

Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

Prevention of protein denaturation under heat stress by the chaperonin Hsp60.

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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S293-310

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scholarly article

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10.3233/JAD-2010-100351

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20 Suppl 2

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2010-01-01T00:00:00Z

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20463402

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Alzheimer's disease

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4175722

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