Asymmetric bidirectional transcription from the FSHD-causing D4Z4 array modulates DUX4 production. - Wikidata - awgldk - TriplyDB

Asymmetric bidirectional transcription from the FSHD-causing D4Z4 array modulates DUX4 production.

Asymmetric bidirectional transcription from the FSHD-causing D4Z4 array modulates DUX4 production.

http://www.wikidata.org/entity/Q34247338

about

Facioscapulohumeral dystrophy: the path to consensus on pathophysiology Facioscapulohumeral muscular dystrophy: consequences of chromatin relaxation Endogenous DUX4 expression in FSHD myotubes is sufficient to cause cell death and disrupts RNA splicing and cell migration pathways Myogenic enhancers regulate expression of the facioscapulohumeral muscular dystrophy-associated DUX4 gene.Polycomb repressive complex 1 provides a molecular explanation for repeat copy number dependency in FSHD muscular dystrophy.Emerging preclinical animal models for FSHD.Facioscapulohumeral muscular dystrophy as a model for epigenetic regulation and disease A repetitive elements perspective in Polycomb epigenetics.Defective regulation of microRNA target genes in myoblasts from facioscapulohumeral dystrophy patients.Wnt/β-catenin signaling suppresses DUX4 expression and prevents apoptosis of FSHD muscle cells.Loss of epigenetic silencing of the DUX4 transcription factor gene in facioscapulohumeral muscular dystrophy.DICER/AGO-dependent epigenetic silencing of D4Z4 repeats enhanced by exogenous siRNA suggests mechanisms and therapies for FSHD.Emerging roles of macrosatellite repeats in genome organization and disease development.A focal domain of extreme demethylation within D4Z4 in FSHD2.Facioscapulohumeral Muscular Dystrophy.

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Asymmetric bidirectional transcription from the FSHD-causing D4Z4 array modulates DUX4 production.

http://www.wikidata.org/entity/Q34247338

description

2012 nî lūn-bûn

@nan

2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2012 թվականի ապրիլին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Asymmetric bidirectional trans ...... ray modulates DUX4 production.

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Asymmetric bidirectional trans ...... ray modulates DUX4 production.

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Asymmetric bidirectional trans ...... ray modulates DUX4 production.

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Asymmetric bidirectional trans ...... ray modulates DUX4 production.

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Asymmetric bidirectional trans ...... ray modulates DUX4 production.

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JOURNAL.PONE.0035532

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Asymmetric bidirectional trans ...... rray modulates DUX4 production

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Amanda M Amell

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Ashlee Tyler

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Divya Narayanan

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Galina N Filippova

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Gregory J Block

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James M Moore

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Lisa M Petek

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Natalia A Rabaia

http://www.w3.org/2001/XMLSchema#string

Rabi Tawil

http://www.w3.org/2001/XMLSchema#string

P2860

Facioscapulohumeral dystrophy: incomplete suppression of a retrotransposed gene

DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1

The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

HOTAIR: Flight of noncoding RNAs in cancer metastasis

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

Specific sequence variations within the 4q35 region are associated with facioscapulohumeral muscular dystrophy

Embryonic stem cell lines derived from human blastocysts

Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element

A unifying genetic model for facioscapulohumeral muscular dystrophy

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e35532

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scholarly article

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10.1371/JOURNAL.PONE.0035532

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Daniel G. Miller

Silvère M van der Maarel

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2012-04-20T00:00:00Z

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224847845

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