MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells. - Wikidata - awgldk - TriplyDB

MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells.

MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells.

http://www.wikidata.org/entity/Q34247686

about

GPER Function in Breast Cancer: An Overview GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response.GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells Estrogen biology: new insights into GPER function and clinical opportunities Effects of atrazine on estrogen receptor α- and G protein-coupled receptor 30-mediated signaling and proliferation in cancer cells and cancer-associated fibroblasts Exogenous hormonal regulation in breast cancer cells by phytoestrogens and endocrine disruptors Copper activates HIF-1α/GPER/VEGF signalling in cancer cells G protein-coupled estrogen receptor in energy homeostasis and obesity pathogenesis.Emerging roles of GPER in diabetes and atherosclerosis.Novel Aspects Concerning the Functional Cross-Talk between the Insulin/IGF-I System and Estrogen Signaling in Cancer Cells.Inhibition of GPR30 by estriol prevents growth stimulation of triple-negative breast cancer cells by 17β-estradiol.International Union of Basic and Clinical Pharmacology. XCVII. G Protein-Coupled Estrogen Receptor and Its Pharmacologic Modulators The effects of (-)-epicatechin on endothelial cells involve the G protein-coupled estrogen receptor (GPER).A calixpyrrole derivative acts as an antagonist to GPER, a G-protein coupled receptor: mechanisms and models.SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer.Macromolecular Modelling and Docking Simulations for the Discovery of Selective GPER Ligands.G protein-coupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17β-estradiol in cancer cells and cancer-associated fibroblasts.Tamoxifen Action in ER-Negative Breast Cancer.Alike but not the same: anatomic heterogeneity of estrogen receptor-mediated vasodilation.Estrogen-dependent downregulation of hypoxia-inducible factor (HIF)-2α in invasive breast cancer cells HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs)Combating malaria with plant molecules: a brief update.GPER, IGF-IR, and EGFR transduction signaling are involved in stimulatory effects of zinc in breast cancer cells and cancer-associated fibroblasts.Identification of two benzopyrroloxazines acting as selective GPER antagonists in breast cancer cells and cancer-associated fibroblasts.G Protein-Coupled Estrogen Receptor (GPER) Agonist Dual Binding Mode Analyses toward Understanding of its Activation Mechanism: A Comparative Homology Modeling Approach A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between stroma and breast carcinoma cells Deciphering the GPER/GPR30-agonist and antagonists interactions using molecular modeling studies, molecular dynamics, and docking simulations.The lauric acid-activated signaling prompts apoptosis in cancer cells.Identification of G protein-coupled estrogen receptor in human and pig spermatozoa.Sex Hormone Receptors in Benign and Malignant Salivary Gland Tumors: Prognostic and Predictive Role.Homology Modeling, Validation and Dynamics of the G Protein-coupled Estrogen Receptor 1 (GPER-1).

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MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells.

http://www.wikidata.org/entity/Q34247686

description

2012 nî lūn-bûn

@nan

2012 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հունվարին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

MIBE acts as antagonist ligand ...... d GPER in breast cancer cells.

@ast

MIBE acts as antagonist ligand ...... d GPER in breast cancer cells.

@en

MIBE acts as antagonist ligand ...... d GPER in breast cancer cells.

@nl

type

label

MIBE acts as antagonist ligand ...... d GPER in breast cancer cells.

@ast

MIBE acts as antagonist ligand ...... d GPER in breast cancer cells.

@en

MIBE acts as antagonist ligand ...... d GPER in breast cancer cells.

@nl

prefLabel

MIBE acts as antagonist ligand ...... d GPER in breast cancer cells.

@ast

MIBE acts as antagonist ligand ...... d GPER in breast cancer cells.

@en

MIBE acts as antagonist ligand ...... d GPER in breast cancer cells.

@nl

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Breast Cancer Research

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MIBE acts as antagonist ligand ...... nd GPER in breast cancer cells

@en

P2093

Anna Caruso

http://www.w3.org/2001/XMLSchema#string

Marco Pupo

http://www.w3.org/2001/XMLSchema#string

Maria Stefania Sinicropi

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Rosamaria Lappano

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P2860

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

Estrogen receptors and human disease

Overexpression, purification, and crystal structure of native ER alpha LBD

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

UCSF Chimera--a visualization system for exploratory research and analysis

PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells

G-protein-coupled receptor 30 and estrogen receptor-alpha are involved in the proliferative effects induced by atrazine in ovarian cancer cells

Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF

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scholarly article

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10.1186/BCR3096

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1

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14

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Marcello Maggiolini

Maria Francesca Santolla

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2012-01-17T00:00:00Z

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221753459

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1044284774

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22251451

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3496129

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