Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.
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Genetic studies of body mass index yield new insights for obesity biologyThe Biodemography of Fertility: A Review and Future Research FrontiersGenetics of the ovarian reserveBRCA Mutations, DNA Repair Deficiency, and Ovarian AgingThe genetics of premature ovarian failure: current perspectivesExome sequencing reveals MCM8 mutation underlies ovarian failure and chromosomal instabilityMCM9 mutations are associated with ovarian failure, short stature, and chromosomal instabilityLarge-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repairImpairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humansReplication of genetic loci for ages at menarche and menopause in the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) studyAnti-Müllerian hormone serum concentrations of women with germline BRCA1 or BRCA2 mutationsAccelerated reproductive aging in females lacking a novel centromere protein SYCP2L.Age at natural menopause genetic risk score in relation to age at natural menopause and primary open-angle glaucoma in a US-based sampleCosmetics use and age at menopause: is there a connection?Meta-analysis of loci associated with age at natural menopause in African-American womenGenomic markers of ovarian reserveEstrogen Effects on the Mammary Gland in Early and Late Life and Breast Cancer RiskThe DNA damage response: the omics era and its impact.Pleiotropic genes for metabolic syndrome and inflammationApproaches to identify genetic variants that influence the risk for onset of fragile X-associated primary ovarian insufficiency (FXPOI): a preliminary study.Epigenetics across the human lifespan.Gene expression and DNA-methylation of bovine pretransfer endometrium depending on its receptivity after in vitro-produced embryo transfer.Menopause accelerates biological aging.Ages at menarche and menopause and reproductive lifespan as predictors of exceptional longevity in women: the Women's Health Initiative.Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study.Evaluating GWAS-identified SNPs for age at natural menopause among chinese women.Multiple hits for the association of uterine fibroids on human chromosome 1q43.Extended maternal age at birth of last child and women's longevity in the Long Life Family Study.A microsatellite polymorphism in IGF1 gene promoter and timing of natural menopause in Caucasian womenAllelic expression mapping across cellular lineages to establish impact of non-coding SNPs.New genetic loci link adipose and insulin biology to body fat distribution.Gene polymorphisms in RANKL/RANK/OPG pathway are associated with ages at menarche and natural menopause in Chinese women.DNA methylome and transcriptome sequencing in human ovarian granulosa cells links age-related changes in gene expression to gene body methylation and 3'-end GC density.Human fertility, molecular genetics, and natural selection in modern societies.Puberty timing associated with diabetes, cardiovascular disease and also diverse health outcomes in men and women: the UK Biobank study.Gene variants associated with age at menopause are also associated with polycystic ovary syndrome, gonadotrophins and ovarian volume.Genomics and successful aging: grounds for renewed optimism?Fine mapping of the uterine leiomyoma locus on 1q43 close to a lncRNA in the RGS7-FH intervalGenome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypesThe Rotterdam Study: 2016 objectives and design update.
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P2860
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
name
Meta-analyses identify 13 loci ...... NA repair and immune pathways.
@ast
Meta-analyses identify 13 loci ...... NA repair and immune pathways.
@en
Meta-analyses identify 13 loci ...... NA repair and immune pathways.
@en-gb
Meta-analyses identify 13 loci ...... NA repair and immune pathways.
@nl
type
label
Meta-analyses identify 13 loci ...... NA repair and immune pathways.
@ast
Meta-analyses identify 13 loci ...... NA repair and immune pathways.
@en
Meta-analyses identify 13 loci ...... NA repair and immune pathways.
@en-gb
Meta-analyses identify 13 loci ...... NA repair and immune pathways.
@nl
prefLabel
Meta-analyses identify 13 loci ...... NA repair and immune pathways.
@ast
Meta-analyses identify 13 loci ...... NA repair and immune pathways.
@en
Meta-analyses identify 13 loci ...... NA repair and immune pathways.
@en-gb
Meta-analyses identify 13 loci ...... NA repair and immune pathways.
@nl
P2093
P2860
P50
P356
P1433
P1476
Meta-analyses identify 13 loci ...... NA repair and immune pathways.
@en
P2093
Aaron R Folsom
Alan F Wright
Albert Tenesa
Alex N Parker
Alice M Arnold
Andrew D Johnson
Andrew S Plump
Angelo Scuteri
Barbara McKnight
Bart C J M Fauser
P2860
P2888
P304
P356
10.1038/NG.1051
P407
P50
P577
2012-01-22T00:00:00Z