Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin.
about
Isolation and characterization of a novel lepidopteran-selective toxin from the venom of South Indian red scorpion, Mesobuthus tamulusCobatoxin 1 from Centruroides noxius scorpion venom: chemical synthesis, three-dimensional structure in solution, pharmacology and docking on K+ channelsScorpions from Mexico: From Species Diversity to Venom ComplexityScorpion toxins specific for potassium (K+) channels: a historical overview of peptide bioengineeringStructure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K + channelA fusion protein containing a lepidopteran-specific toxin from the South Indian red scorpion (Mesobuthus tamulus) and snowdrop lectin shows oral toxicity to target insects.Isolation of the first toxin from the scorpion Buthus occitanus israelis showing preference for Shaker potassium channels.Use of venom peptides to probe ion channel structure and function.Mapping the receptor site for ergtoxin, a specific blocker of ERG channels.A novel structural class of K+-channel blocking toxin from the scorpion Pandinus imperator.A new scorpion venom toxin paralytic to insects that affects Na+ channel activation. Purification, structure, antigenicity and mode of action.Subunit composition of brain voltage-gated potassium channels determined by hongotoxin-1, a novel peptide derived from Centruroides limbatus venom.Primary structure of a potassium channel toxin from the sea anemone Actinia equina.Toxins Targeting the Kv1.3 Channel: Potential Immunomodulators for Autoimmune DiseasesComparison of the effects of the K(+)-channel openers cromakalim and minoxidil sulphate on vascular smooth muscle.Charybdotoxin blocks voltage-gated K+ channels in human and murine T lymphocytes.Pandinus imperator scorpion venom blocks voltage-gated potassium channels in GH3 cells.K+ channel modulators for the treatment of neurological disorders and autoimmune diseasesTreating autoimmune disorders with venom-derived peptides.A molecular description of nerve terminal function.Venom Gland Transcriptomic and Proteomic Analyses of the Enigmatic Scorpion Superstitionia donensis (Scorpiones: Superstitioniidae), with Insights on the Evolution of Its Venom Components.Tetrapandins, a new class of scorpion toxins that specifically inhibit store-operated calcium entry in human embryonic kidney-293 cells.Isolation, purification, and N-terminal partial sequence of an antitumor peptide from the venom of the Chinese scorpion Buthus martensii Karsch.Recombinant scorpion insectotoxin AaIT kills specifically insect cells but not human cells.Potassium channel toxins and transmitter release.Scorpion toxins from Centruroides noxius and Tityus serrulatus. Primary structures and sequence comparison by metric analysis.Amino acid sequence and immunological characterization with monoclonal antibodies of two toxins from the venom of the scorpion Centruroides noxius Hoffmann.Toxic peptides and genes encoding toxin gamma of the Brazilian scorpions Tityus bahiensis and Tityus stigmurus.Novel K(+)-channel-blocking toxins from the venom of the scorpion Centruroides limpidus limpidus Karsch.Characterization of potassium currents modulated by BRL 38227 in rat portal vein.Site directed mutants of Noxiustoxin reveal specific interactions with potassium channels.Application of an ectopic expression system for the selection of protein-isoform-specific antibodies. The monoclonal antibody K1C3 is specific for the RCK1 potassium channel.Primary structure determination and cloning of the cDNA encoding toxin 4 of the scorpion Centruroides noxius Hoffmann.Purinergic modulation of hippocampal acetylcholine release involves alpha-dendrotoxin-sensitive potassium channels.Molecular docking of the scorpion toxin Tc1 to the structural model of the voltage-gated potassium channel Kv1.1 from human Homo sapiens.Characterization of the actions of toxins II-9.2.2 and II-10 from the venom of the scorpion Centruroides noxius on transmitter release from mouse brain synaptosomes.The disulfide bridges of toxin 2 from the scorpion Centruroides noxius Hoffmann and its three-dimensional structure calculated using the coordinates of variant 3 from Centruroides sculpturatus.The Assessment of QT/QTc Interval Prolongation in Clinical Trials: A Regulatory PerspectiveK1.3 channel blockade with the Vm24 scorpion toxin attenuates the CD4 effector memory T cell response to TCR stimulation
P2860
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P2860
Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin.
description
1982 nî lūn-bûn
@nan
1982 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1982 թվականի մարտին հրատարակված գիտական հոդված
@hy
1982年の論文
@ja
1982年論文
@yue
1982年論文
@zh-hant
1982年論文
@zh-hk
1982年論文
@zh-mo
1982年論文
@zh-tw
1982年论文
@wuu
name
Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin.
@ast
Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin.
@en
Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin.
@nl
type
label
Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin.
@ast
Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin.
@en
Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin.
@nl
prefLabel
Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin.
@ast
Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin.
@en
Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin.
@nl
P2093
P2860
P356
P1433
P1476
Selective blockage of voltage-dependent K+ channels by a novel scorpion toxin
@en
P2093
A Maelicke
G Prestipino
L D Possani
P2860
P2888
P356
10.1038/296090A0
P407
P577
1982-03-01T00:00:00Z
P5875
P6179
1004925996