The immunoglobulin heavy chain locus: genetic variation, missing data, and implications for human disease.
about
The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage.The human IgE repertoirePractical guidelines for B-cell receptor repertoire sequencing analysisProduction of individualized V gene databases reveals high levels of immunoglobulin genetic diversityAutomated analysis of high-throughput B-cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles.Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution.Visualization and probability-based scoring of structural variants within repetitive sequences.Association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania.Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.Soma-to-germline feedback is implied by the extreme polymorphism at IGHV relative to MHC: The manifest polymorphism of the MHC appears greatly exceeded at Immunoglobulin loci, suggesting antigen-selected somatic V mutants penetrate Weismann's BarrieFine mapping of V(D)J recombinase mediated rearrangements in human lymphoid malignanciesSequencing of the human IG light chain loci from a hydatidiform mole BAC library reveals locus-specific signatures of genetic diversityAbility to develop broadly neutralizing HIV-1 antibodies is not restricted by the germline Ig gene repertoire.Estimating Copy Number and Allelic Variation at the Immunoglobulin Heavy Chain Locus Using Short Reads.Cross-reactive and pre-existing antibodies to therapeutic antibodies--Effects on treatment and immunogenicity.DJ Pairing during VDJ Recombination Shows Positional Biases That Vary among Individuals with Differing IGHD Locus ImmunogenotypesShort-term assessment of BCR repertoires of SLE patients after high dose glucocorticoid therapy with high-throughput sequencingIGHV1-69 polymorphism modulates anti-influenza antibody repertoires, correlates with IGHV utilization shifts and varies by ethnicityComplete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variationCharacterization of pathogenic human monoclonal autoantibodies against GM-CSF.The shape of the lymphocyte receptor repertoire: lessons from the B cell receptorThe Individual and Population Genetics of Antibody Immunity.Evolution of B cell analysis and Env trimer redesign.A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol.A Streamlined Approach to Antibody Novel Germline Allele Prediction and Validation.Annotation of pseudogenic gene segments by massively parallel sequencing of rearranged lymphocyte receptor lociStructures of Preferred Human IgV Genes-Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation.Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CAHypertensive renal injury is associated with gene variation affecting immune signaling.Universal influenza virus vaccines: what can we learn from the human immune response following exposure to H7 subtype viruses?An automated algorithm for extracting functional immunologic V-genes from genomes in jawed vertebrates.On being the right size: antibody repertoire formation in the mouse and human.A murine Ig light chain transgene reveals IGKV3 gene contributions to anti-collagen types IV and II specificities.Heritability of vaccine-induced measles neutralizing antibody titers.In Vitro Evolution of Antibodies Inspired by In Vivo Evolution.Immunoglobulin Light Chain Gene Rearrangements, Receptor Editing and the Development of a Self-Tolerant Antibody Repertoire
P2860
Q22065285-D29AE7B3-BEED-4D84-820A-24AA1ACEA13EQ26865573-EC0CD4EE-3969-4AD0-B473-8F8572263351Q28607156-6B4684D7-AD85-4F93-AFDF-5B6326ABC951Q28818629-F2321716-A615-4E8B-9E27-694896EF8B38Q30891515-6344729D-048F-4DAF-B362-F3A127C611D4Q33627189-22BD4168-19CD-4AF7-B745-E5882EFCC4F0Q33641952-BAD8984E-E603-473F-8706-E0727F8B2D0EQ33705559-046B94C6-C59F-42FF-B75D-F79556ECC803Q33747916-AA1E9B1F-1678-4B57-A607-352E9FCC303AQ34468679-87320B27-3D9D-47BA-8D77-2949C6EEBF29Q34956008-33D1ACDD-358B-4A51-A6B8-D2AE43455DB7Q35007784-B8E7996D-228B-434D-ABEF-9F9C9162AE02Q35883727-020F454C-C882-4F4C-831B-FA5E4AAED089Q36134501-266B72A0-E69B-4C71-B47E-B2506DBAB06FQ36214720-8D6525FF-7BE9-4B9B-9EF3-93C2E83E3F4DQ36494999-11B126B7-184E-4032-9A77-ED3DB26EC980Q36501620-EF5BF444-5991-448F-B9C4-A766742F0C8FQ36583070-9352B60C-EF5B-482F-926F-433B87D4E0FEQ36742607-DED0E758-9E42-42C2-B9DF-79F1FAF1EDEDQ36835759-0EEE3B28-F33B-4318-8503-7D5C379E40ACQ37137346-1266C108-204D-41A2-B764-60886ADB121AQ38766578-F2140D6A-0355-4A92-AB7C-35C092ED0765Q38992740-7A6A73C6-949B-46D9-A8DA-3F6FCB53AFB5Q41196820-CF79BCD3-3ACC-42B2-A35C-E6BB922B54BDQ41468626-85352CD7-F702-4097-8703-F71147808B00Q41981966-A16E017C-41E0-48F0-A8EF-DA28A55D0C9DQ42069312-BDC971D2-357F-4F31-BCA8-D3A79272A974Q42557137-A9E166E2-C710-4943-B6AE-13F57DD9754DQ43071752-2F6AA91A-2257-4A16-8224-36904058EC64Q45324518-1DF3F392-AD41-4D7A-81FF-845EDF3C8475Q46655076-47D4E254-1706-401C-82DF-DFC0150287E1Q47173421-D3C4D128-5E27-4ADB-B5CE-DDADFB557D05Q47833098-A9970F3A-86F7-4B53-8FEC-E39FDCD00D2EQ47892454-5C528205-1312-41AF-AE50-917EFF76DCBFQ55426539-9E13CFDB-152A-442A-9FD6-F33B55910C35Q57817492-E46E2356-3911-44F7-9D6C-D92825627FD6
P2860
The immunoglobulin heavy chain locus: genetic variation, missing data, and implications for human disease.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The immunoglobulin heavy chain ...... mplications for human disease.
@ast
The immunoglobulin heavy chain ...... mplications for human disease.
@en
The immunoglobulin heavy chain ...... mplications for human disease.
@nl
type
label
The immunoglobulin heavy chain ...... mplications for human disease.
@ast
The immunoglobulin heavy chain ...... mplications for human disease.
@en
The immunoglobulin heavy chain ...... mplications for human disease.
@nl
prefLabel
The immunoglobulin heavy chain ...... mplications for human disease.
@ast
The immunoglobulin heavy chain ...... mplications for human disease.
@en
The immunoglobulin heavy chain ...... mplications for human disease.
@nl
P2860
P356
P1433
P1476
The immunoglobulin heavy chain ...... mplications for human disease.
@en
P2093
P2860
P2888
P304
P356
10.1038/GENE.2012.12
P577
2012-05-03T00:00:00Z
P5875
P6179
1021553554