Valproic acid induces differentiation and transient tumor regression, but spares leukemia-initiating activity in mouse models of APL.
about
Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agentsInhibition of histone deacetylases in cancer therapy: lessons from leukaemiaThe roles of retinoic acid and retinoic acid receptors in inducing epigenetic changesDasatinib accelerates valproic acid-induced acute myeloid leukemia cell death by regulation of differentiation capacity10058-F4, a c-Myc inhibitor, markedly increases valproic acid-induced cell death in Jurkat and CCRF-CEM T-lymphoblastic leukemia cells.Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitorsAntagonism between granulocytic maturation and deacetylase inhibitor-induced apoptosis in acute promyelocytic leukaemia cellsSelective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia.Uncoupling RARA transcriptional activation and degradation clarifies the bases for APL response to therapies.Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic developmentTargeting of histone deacetylases to reactivate tumour suppressor genes and its therapeutic potential in a human cervical cancer xenograft model.Anticancer effects of valproic acid on oral squamous cell carcinoma via SUMOylation in vivo and in vitro.Regulation of self-renewal in normal and cancer stem cells.Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders.Epigenetics in acute promyelocytic leukaemia pathogenesis and treatment response: a TRAnsition to targeted therapies.Epigenetic alterations in acute myeloid leukemias.Unlocking the potential of retinoic acid in anticancer therapy.Cancer stem cells in prostate cancer.How do tumor cells respond to HDAC inhibition?Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells.Histone Acetyltransferase p300/CREB-binding Protein-associated Factor (PCAF) Is Required for All-trans-retinoic Acid-induced Granulocytic Differentiation in Leukemia Cells.The acute promyelocytic leukaemia success story: curing leukaemia through targeted therapies.
P2860
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P2860
Valproic acid induces differentiation and transient tumor regression, but spares leukemia-initiating activity in mouse models of APL.
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Valproic acid induces differen ...... tivity in mouse models of APL.
@ast
Valproic acid induces differen ...... tivity in mouse models of APL.
@en
Valproic acid induces differen ...... tivity in mouse models of APL.
@nl
type
label
Valproic acid induces differen ...... tivity in mouse models of APL.
@ast
Valproic acid induces differen ...... tivity in mouse models of APL.
@en
Valproic acid induces differen ...... tivity in mouse models of APL.
@nl
prefLabel
Valproic acid induces differen ...... tivity in mouse models of APL.
@ast
Valproic acid induces differen ...... tivity in mouse models of APL.
@en
Valproic acid induces differen ...... tivity in mouse models of APL.
@nl
P2093
P2860
P356
P1433
P1476
Valproic acid induces differen ...... tivity in mouse models of APL.
@en
P2093
C Mercurio
I Pallavicini
R Dal Zuffo
P2860
P2888
P304
P356
10.1038/LEU.2012.39
P577
2012-02-15T00:00:00Z
P5875
P6179
1030855365