ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis
about
Activation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replicationA novel motif in the Crohn's disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responsesMechanisms of Microbe-Host Interaction in Crohn's Disease: Dysbiosis vs. Pathobiont SelectionFrom genetics of inflammatory bowel disease towards mechanistic insightsNOD-Like Receptors: Master Regulators of Inflammation and CancerVitamin D, immune regulation, the microbiota, and inflammatory bowel diseaseRIP2 activity in inflammatory disease and implications for novel therapeuticsThe role of innate immunity receptors in the pathogenesis of inflammatory bowel diseaseGenetically determined epithelial dysfunction and its consequences for microflora-host interactionsInflammatory Bowel Disease Drugs: A Focus on AutophagyResearch Advance in Intestinal Mucosal Barrier and Pathogenesis of Crohn's DiseaseNod2: A Critical Regulator of Ileal Microbiota and Crohn's DiseaseInternational Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and diseaseATG16L1: A multifunctional susceptibility factor in Crohn diseaseVitamin D differentially regulates Salmonella-induced intestine epithelial autophagy and interleukin-1β expressionThe N-terminal region of the human autophagy protein ATG16L1 contains a domain that folds into a helical structure consistent with formation of a coiled-coilIntegrated enrichment analysis of variants and pathways in genome-wide association studies indicates central role for IL-2 signaling genes in type 1 diabetes, and cytokine signaling genes in Crohn's diseaseEhrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinaseNLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STINGGenetic variation in IBD: progress, clues to pathogenesis and possible clinical utilityAutophagosomes induced by a bacterial Beclin 1 binding protein facilitate obligatory intracellular infectionIntestinal epithelial autophagy is essential for host defense against invasive bacteriaNOD2-mediated suppression of CD55 on neutrophils enhances C5a generation during polymicrobial sepsis.An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomesHeme oxygenase-1 and carbon monoxide regulate intestinal homeostasis and mucosal immune responses to the enteric microbiota.Human autophagy gene ATG16L1 is post-transcriptionally regulated by MIR142-3pMicrobiota activation and regulation of innate and adaptive immunity.Host genetic susceptibility, dysbiosis, and viral triggers in inflammatory bowel disease.Alcohol-induced autophagy contributes to loss in skeletal muscle mass.Genetic and functional profiling of Crohn's disease: autophagy mechanism and susceptibility to infectious diseasesThe critical role of membrane cholesterol in salmonella-induced autophagy in intestinal epithelial cells.The role of bacteria and pattern-recognition receptors in Crohn's disease.Host and gut microbiota symbiotic factors: lessons from inflammatory bowel disease and successful symbionts.Infectious etiopathogenesis of Crohn's diseaseProhibitin 1 modulates mitochondrial stress-related autophagy in human colonic epithelial cells.Nod2: a key regulator linking microbiota to intestinal mucosal immunity.Activation of pattern recognition receptors up-regulates metallothioneins, thereby increasing intracellular accumulation of zinc, autophagy, and bacterial clearance by macrophagesIκB kinase α phosphorylation of TRAF4 downregulates innate immune signaling.Etiology of Crohn's disease: many roads lead to autophagy.Autophagy as a stress-response and quality-control mechanism: implications for cell injury and human disease
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P2860
ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
ATG16L1 and NOD2 interact in a ...... n Crohn's disease pathogenesis
@ast
ATG16L1 and NOD2 interact in a ...... n Crohn's disease pathogenesis
@en
ATG16L1 and NOD2 interact in a ...... n Crohn's disease pathogenesis
@nl
type
label
ATG16L1 and NOD2 interact in a ...... n Crohn's disease pathogenesis
@ast
ATG16L1 and NOD2 interact in a ...... n Crohn's disease pathogenesis
@en
ATG16L1 and NOD2 interact in a ...... n Crohn's disease pathogenesis
@nl
prefLabel
ATG16L1 and NOD2 interact in a ...... n Crohn's disease pathogenesis
@ast
ATG16L1 and NOD2 interact in a ...... n Crohn's disease pathogenesis
@en
ATG16L1 and NOD2 interact in a ...... n Crohn's disease pathogenesis
@nl
P2093
P2860
P1433
P1476
ATG16L1 and NOD2 interact in a ...... n Crohn's disease pathogenesis
@en
P2093
Amy L Richmond
Christine McDonald
Craig R Homer
Jean-Paul Achkar
Nancy A Rebert
P2860
P304
1630-41, 1641.e1-2
P356
10.1053/J.GASTRO.2010.07.006
P407
P577
2010-07-14T00:00:00Z