Bloom's syndrome and PICH helicases cooperate with topoisomerase IIα in centromere disjunction before anaphase - Wikidata - awgldk - TriplyDB

Bloom's syndrome and PICH helicases cooperate with topoisomerase IIα in centromere disjunction before anaphase

Bloom's syndrome and PICH helicases cooperate with topoisomerase IIα in centromere disjunction before anaphase

http://www.wikidata.org/entity/Q34259623

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PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis DDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approach Novel subcellular localization of the DNA helicase Twinkle at the kinetochore complex during mitosis in neuronal-like progenitor cells.TopoIIα prevents telomere fragility and formation of ultra thin DNA bridges during mitosis through TRF1-dependent binding to telomeres Mitotic catenation is monitored and resolved by a PKCε-regulated pathway Next-generation transcriptome sequencing of the premenopausal breast epithelium using specimens from a normal human breast tissue bank.Rescue from replication stress during mitosis.Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA.Cdk5 promotes DNA replication stress checkpoint activation through RPA-32 phosphorylation, and impacts on metastasis free survival in breast cancer patients.The BLM dissolvasome in DNA replication and repair.How unfinished business from S-phase affects mitosis and beyond Smc5/6-mediated regulation of replication progression contributes to chromosome assembly during mitosis in human cells.PICH promotes mitotic chromosome segregation: Identification of a novel role in rDNA disjunction.Mitotic phosphorylation of Bloom helicase at Thr182 is required for its proteasomal degradation and maintenance of chromosomal stability.Genomic rearrangements induced by unscheduled DNA double strand breaks in somatic mammalian cells.Bloom syndrome radials are predominantly non-homologous and are suppressed by phosphorylated BLM ERCC6L, a DNA helicase, is involved in cell proliferation and associated with survival and progress in breast and kidney cancers.SUMO-interacting motifs (SIMs) in Polo-like kinase 1-interacting checkpoint helicase (PICH) ensure proper chromosome segregation during mitosis.Cytidine deaminase deficiency impairs sister chromatid disjunction by decreasing PARP-1 activity.A tri-serine cluster within the topoisomerase IIα-interaction domain of the BLM helicase is required for regulating chromosome breakage in human cells.Proper sister chromatid disjunction requires CDA and PARP-1.The dark side of centromeres: types, causes and consequences of structural abnormalities implicating centromeric DNA Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality

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P2860

Bloom's syndrome and PICH helicases cooperate with topoisomerase IIα in centromere disjunction before anaphase

http://www.wikidata.org/entity/Q34259623

description

2012 nî lūn-bûn

@nan

2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2012 թվականի ապրիլին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Bloom's syndrome and PICH heli ...... re disjunction before anaphase

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Bloom's syndrome and PICH heli ...... re disjunction before anaphase

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Bloom's syndrome and PICH heli ...... re disjunction before anaphase

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Bloom's syndrome and PICH heli ...... re disjunction before anaphase

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Bloom's syndrome and PICH heli ...... re disjunction before anaphase

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Bloom's syndrome and PICH heli ...... re disjunction before anaphase

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prefLabel

Bloom's syndrome and PICH heli ...... re disjunction before anaphase

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Bloom's syndrome and PICH heli ...... re disjunction before anaphase

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Bloom's syndrome and PICH heli ...... re disjunction before anaphase

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JOURNAL.PONE.0033905

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Bloom's syndrome and PICH heli ...... re disjunction before anaphase

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Christian Jaulin

http://www.w3.org/2001/XMLSchema#string

Géraldine Buhagiar-Labarchède

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Ilse Hurbain

http://www.w3.org/2001/XMLSchema#string

Laura Magnaghi-Jaulin

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Mounira Amor-Guéret

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Rosine Onclercq-Delic

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Simon Gemble

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Sébastien Rouzeau

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P2860

Nuclear structure in normal and Bloom syndrome cells

Structural and functional analyses of disease-causing missense mutations in Bloom syndrome protein

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport

A guided tour into subcellular colocalization analysis in light microscopy

Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling

High precision size measurement of centromere 8 and the 8q24/c-myc gene region in metaphase and interphase human fibroblasts indicate differential condensation.

Topoisomerase IIbeta activates a subset of neuronal genes that are repressed in AT-rich genomic environment.

PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution.

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e33905

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scholarly article

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10.1371/JOURNAL.PONE.0033905

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4

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Fabrice P Cordelières

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2012-04-26T00:00:00Z

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224915851

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3338505

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