A modified hepatitis B virus core particle containing multiple epitopes of the Plasmodium falciparum circumsporozoite protein provides a highly immunogenic malaria vaccine in preclinical analyses in rodent and primate hosts

A modified hepatitis B virus core particle containing multiple epitopes of the Plasmodium falciparum circumsporozoite protein provides a highly immunogenic malaria vaccine in preclinical analyses in rodent and primate hosts

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http://www.wikidata.org/entity/Q34261339

Q34261339

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Phase I trial of an alhydrogel adjuvanted hepatitis B core virus-like particle containing epitopes of Plasmodium falciparum circumsporozoite protein.Why functional pre-erythrocytic and bloodstage malaria vaccines fail: a meta-analysis of fully protective immunizations and novel immunological model.Subviral particle as vaccine and vaccine platform.Development of a Novel Virus-Like Particle Vaccine Platform That Mimics the Immature Form of Alphavirus.Roles of the amino terminal region and repeat region of the Plasmodium berghei circumsporozoite protein in parasite infectivity M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.P. falciparum and P. vivax Epitope-Focused VLPs Elicit Sterile Immunity to Blood Stage Infections.Tandem fusion of hepatitis B core antigen allows assembly of virus-like particles in bacteria and plants with enhanced capacity to accommodate foreign proteins A nonadjuvanted polypeptide nanoparticle vaccine confers long-lasting protection against rodent malaria.Challenges facing adjuvants for cancer immunotherapy.Building better T-cell-inducing malaria vaccines.Malaria vaccines in development.Combination of protein and viral vaccines induces potent cellular and humoral immune responses and enhanced protection from murine malaria challenge.Pre-erythrocytic malaria vaccines: towards greater efficacy.Plasmodium falciparum synthetic LbL microparticle vaccine elicits protective neutralizing antibody and parasite-specific cellular immune responses.Combination vaccines: synergistic simultaneous induction of antibody and T-cell immunity.Use of hepadnavirus core proteins as vaccine platforms.Production of recombinant proteins from protozoan parasites.Viral nanoparticles and virus-like particles: platforms for contemporary vaccine design.Synergism/complementarity of recombinant adenoviral vectors and other vaccination platforms during induction of protective immunity against malaria.Plasmodium falciparum malaria vaccines: current status, pitfalls and future directions.Hepatitis B core-based virus-like particles to present heterologous epitopes.Phase I testing of a malaria vaccine composed of hepatitis B virus core particles expressing Plasmodium falciparum circumsporozoite epitopes.Safety and enhanced immunogenicity of a hepatitis B core particle Plasmodium falciparum malaria vaccine formulated in adjuvant Montanide ISA 720 in a phase I trial Induction of cell-mediated immune responses to peptide antigens of P. vivax in microparticles using intranasal immunization.Coinoculation with hepatitis B surface and core antigen promotes a Th1 immune response to a multiepitopic protein of HIV-1.Elucidation of immunological response and its regulatory network by P-TUFT-ALT-2: a promising fusion protein vaccine for human lymphatic filariasis.Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau.P301S mouse model of Alzheimer's disease and frontotemporal dementia.

P2860

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P2860

A modified hepatitis B virus core particle containing multiple epitopes of the Plasmodium falciparum circumsporozoite protein provides a highly immunogenic malaria vaccine in preclinical analyses in rodent and primate hosts

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http://www.wikidata.org/entity/Q34261339

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2002 nî lūn-bûn

@nan

2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

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