Recent H3N2 influenza virus clinical isolates rapidly acquire hemagglutinin or neuraminidase mutations when propagated for antigenic analyses

Recent H3N2 influenza virus clinical isolates rapidly acquire hemagglutinin or neuraminidase mutations when propagated for antigenic analyses

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http://www.wikidata.org/entity/Q34262280
Influenza viruses with receptor-binding N1 neuraminidases occur sporadically in several lineages and show no attenuation in cell culture or mice.Haemagglutinin mutations and glycosylation changes shaped the 2012/13 influenza A(H3N2) epidemic, Houston, Texas.Novel Sequence-Based Mapping of Recently Emerging H5NX Influenza Viruses Reveals Pandemic Vaccine Candidates.Effects of egg-adaptation on receptor-binding and antigenic properties of recent influenza A (H3N2) vaccine viruses.Cooperation between distinct viral variants promotes growth of H3N2 influenza in cell culture.Neuraminidase-mediated haemagglutination of recent human influenza A(H3N2) viruses is determined by arginine 150 flanking the neuraminidase catalytic site.Directed selection of influenza virus produces antigenic variants that match circulating human virus isolates and escape from vaccine-mediated immune protection.A new role of neuraminidase (NA) in the influenza virus life cycle: implication for developing NA inhibitors with novel mechanism of action.From Variation of Influenza Viral Proteins to Vaccine Development.Aptamer-based biosensors for the rapid visual detection of flu viruses.Cooperating H3N2 Influenza Virus Variants Are Not Detectable in Primary Clinical Samples.Integrating patient and whole-genome sequencing data to provide insights into the epidemiology of seasonal influenza A(H3N2) viruses.Poor immunogenicity, not vaccine strain egg adaptation, may explain the low H3N2 influenza vaccine effectiveness in 2012-13.H3N2 influenza viruses in humans: Viral mechanisms, evolution, and evaluation.
P2860

Recent H3N2 influenza virus clinical isolates rapidly acquire hemagglutinin or neuraminidase mutations when propagated for antigenic analyses

Item
http://www.wikidata.org/entity/Q34262280
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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Recent H3N2 influenza virus cl ...... pagated for antigenic analyses
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Recent H3N2 influenza virus cl ...... pagated for antigenic analyses
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Recent H3N2 influenza virus cl ...... pagated for antigenic analyses
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Recent H3N2 influenza virus cl ...... pagated for antigenic analyses
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