Genetic inhibition of solute-linked carrier 39 family transporter 1 ameliorates aβ pathology in a Drosophila model of Alzheimer's disease
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Loss of Polo ameliorates APP-induced Alzheimer's disease-like symptoms in DrosophilaFunctional studies of Drosophila zinc transporters reveal the mechanism for dietary zinc absorption and regulation.Drosophila melanogaster as a model organism for Alzheimer's disease.Zinc binding directly regulates tau toxicity independent of tau hyperphosphorylation.A commonly used Drosophila model of Alzheimer's disease generates an aberrant species of amyloid-β with an additional N-terminal glutamine residue.Metal Homeostasis Regulators Suppress FRDA Phenotypes in a Drosophila Model of the DiseaseFunctional studies of Drosophila zinc transporters reveal the mechanism for zinc excretion in Malpighian tubules.Zinc homeostasis and neurodegenerative disordersA recessive X-linked mutation causes a threefold reduction of total body zinc accumulation in Drosophila melanogaster laboratory strains.Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease-like symptomsAmyloid peptides ABri and ADan show differential neurotoxicity in transgenic Drosophila models of familial British and Danish dementia.Metallostasis and amyloid β-degrading enzymes.Lysosomal metal, redox and proton cycles influencing the CysHis cathepsin reaction.Fruit flies as a powerful model to drive or validate pain genomics efforts.Biological metals and metal-targeting compounds in major neurodegenerative diseases.Behind the curtain of tauopathy: a show of multiple players orchestrating tau toxicity.Anti-Aβ single-chain variable fragment antibodies restore memory acquisition in a Drosophila model of Alzheimer's diseaseCopper and Zinc Homeostasis: Lessons from Drosophila melanogaster.Phenotypic differences between Drosophila Alzheimer’s disease models expressing human Aβ42 in the developing eye and brain
P2860
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P2860
Genetic inhibition of solute-linked carrier 39 family transporter 1 ameliorates aβ pathology in a Drosophila model of Alzheimer's disease
description
2012 nî lūn-bûn
@nan
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Genetic inhibition of solute-l ...... a model of Alzheimer's disease
@ast
Genetic inhibition of solute-l ...... a model of Alzheimer's disease
@en
Genetic inhibition of solute-l ...... a model of Alzheimer's disease
@nl
type
label
Genetic inhibition of solute-l ...... a model of Alzheimer's disease
@ast
Genetic inhibition of solute-l ...... a model of Alzheimer's disease
@en
Genetic inhibition of solute-l ...... a model of Alzheimer's disease
@nl
prefLabel
Genetic inhibition of solute-l ...... a model of Alzheimer's disease
@ast
Genetic inhibition of solute-l ...... a model of Alzheimer's disease
@en
Genetic inhibition of solute-l ...... a model of Alzheimer's disease
@nl
P2093
P2860
P921
P1433
P1476
Genetic inhibition of solute-l ...... a model of Alzheimer's disease
@en
P2093
Minglin Lang
Qiangwang Fan
Xiaoxi Wang
P2860
P304
P356
10.1371/JOURNAL.PGEN.1002683
P577
2012-04-26T00:00:00Z