The structural basis of the multiple forms of human complement component C4.
about
Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4AFibulin is an extracellular matrix and plasma glycoprotein with repeated domain structurePrimary structure of human complement component C2. Homology to two unrelated protein familiesThe principal site of glycation of human complement factor BStructural basis of the polymorphism of human complement components C4A and C4B: gene size, reactivity and antigenicity.Shared HLA class II-associated genetic susceptibility and resistance, related to the HLA-DQB1 gene, in IgA deficiency and common variable immunodeficiencyHuman complement component C3: cDNA coding sequence and derived primary structurePartial primary structure of human pregnancy zone protein: extensive sequence homology with human alpha 2-macroglobulinComplete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: a pseudogene and a genuine geneStructure and expression of fibulin-2, a novel extracellular matrix protein with multiple EGF-like repeats and consensus motifs for calcium bindingHLA associations with inclusion body myositisCovalent binding properties of the human complement protein C4 and hydrolysis rate of the internal thioester upon activationThe internal thioester and the covalent binding properties of the complement proteins C3 and C4Two mechanisms for mannose-binding protein modulation of the activity of its associated serine proteasesMolecular characterization of the HLA-linked steroid 21-hydroxylase B gene from an individual with congenital adrenal hyperplasiaInfectious diseases associated with complement deficiencies.Differential exoprotease activities confer tumor-specific serum peptidome patternsA new CYP21A1P/CYP21A2 chimeric gene identified in an Italian woman suffering from classical congenital adrenal hyperplasia form.Partial complement deficiencies in idiopathic thrombocytopenia of childhood.Characterization of frequent deletions causing steroid 21-hydroxylase deficiency.21-hydroxylase deficiency families with HLA identical affected and unaffected sibs.C4 null phenotypes among lupus erythematosus patients are predominantly the result of deletions covering C4 and closely linked 21-hydroxylase A genes.Serum proteome changes in acromegalic patients following transsphenoidal surgery: novel biomarkers of disease activity.Conservation of structural and functional domains in complement component C3 of Xenopus and mammals.Sulfation of tyrosine residues increases activity of the fourth component of complement.Modular variations of the human major histocompatibility complex class III genes for serine/threonine kinase RP, complement component C4, steroid 21-hydroxylase CYP21, and tenascin TNX (the RCCX module). A mechanism for gene deletions and disease asMRC OX-2 antigen: a lymphoid/neuronal membrane glycoprotein with a structure like a single immunoglobulin light chainLack of evidence of a specific role for C4A gene deficiency in determining disease susceptibility among C4-deficient patients with systemic lupus erythematosus (SLE).Murine complement component C4 and sex-limited protein: identification of amino acid residues essential for C4 function.Transcript encoded on the opposite strand of the human steroid 21-hydroxylase/complement component C4 gene locusSequence of extracellular mouse protein BM-90/fibulin and its calcium-dependent binding to other basement-membrane ligands.Gene conversion-like events cause steroid 21-hydroxylase deficiency in congenital adrenal hyperplasia.Linkage map of the human major histocompatibility complex including the tumor necrosis factor genes.The phylogeny and evolution of the thioester bond-containing proteins C3, C4 and alpha 2-macroglobulin.Polymorphism of the human complement C4 and steroid 21-hydroxylase genes. Restriction fragment length polymorphisms revealing structural deletions, homoduplications, and size variants.Molecular characterization of human Ro/SS-A antigen. Amino terminal sequence of the protein moiety of human Ro/SS-A antigen and immunological activity of a corresponding synthetic peptideRearrangements and point mutations of P450c21 genes are distinguished by five restriction endonuclease haplotypes identified by a new probing strategy in 57 families with congenital adrenal hyperplasia.Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.C3bi receptor (complement receptor type 3) recognizes a region of complement protein C3 containing the sequence Arg-Gly-Asp.Total C4B deficiency due to gene deletion and gene conversion in a patient with severe infections.
P2860
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P2860
The structural basis of the multiple forms of human complement component C4.
description
1984 nî lūn-bûn
@nan
1984 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1984 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
name
The structural basis of the multiple forms of human complement component C4.
@ast
The structural basis of the multiple forms of human complement component C4.
@en
The structural basis of the multiple forms of human complement component C4.
@nl
type
label
The structural basis of the multiple forms of human complement component C4.
@ast
The structural basis of the multiple forms of human complement component C4.
@en
The structural basis of the multiple forms of human complement component C4.
@nl
prefLabel
The structural basis of the multiple forms of human complement component C4.
@ast
The structural basis of the multiple forms of human complement component C4.
@en
The structural basis of the multiple forms of human complement component C4.
@nl
P2093
P1433
P1476
The structural basis of the multiple forms of human complement component C4.
@en
P2093
P304
P356
10.1016/0092-8674(84)90040-0
P407
P577
1984-04-01T00:00:00Z