Gene amplification in a leukemic patient treated with methotrexate.
about
Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patientsDifferent Facets of Copy Number Changes: Permanent, Transient, and AdaptiveDHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repairOverlooking evolution: a systematic analysis of cancer relapse and therapeutic resistance research.Mithramycin inhibits SP1 binding and selectively inhibits transcriptional activity of the dihydrofolate reductase gene in vitro and in vivo.Frequencies of independent and simultaneous selection of Chinese hamster cells for methotrexate and doxorubicin (adriamycin) resistanceDeterminants of the sensitivity of human small-cell lung cancer cell lines to methotrexate.The emergence of resistance to targeted cancer therapeutics.Resistance to antifolates.The role of the replication licensing system in cell proliferation and cancer.Clinical relevance of P-glycoprotein in drug therapy.Cancer research meets evolutionary biology.Fifth Gordon Hamilton-Fairley memorial lecture. Methotrexate resistance and gene amplification: an experimental model for the generation of cellular heterogeneityMechanisms of antifolate resistance and methotrexate efficacy in leukemia cells.Gene amplification: an example of accelerated evolution in tumorigenic cellsNormal diploid human and rodent cells lack a detectable frequency of gene amplification.Pharmacokinetics and metabolism of methotrexate: an example for the use of clinical pharmacology in pediatric oncology.DNA repair: relationship to drug and radiation resistance, metastasis and growth factors.Genes involved in the determination of the rate of inversions at short inverted repeats.Human myeloma cells acquire resistance to difluoromethylornithine by amplification of ornithine decarboxylase gene.Cancer chemotherapy: targeting folic acid synthesis.Mechanism of methotrexate-sensitivity of choriocarcinoma cells in culture.Molecular analysis of gene amplification in tumors.
P2860
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P2860
Gene amplification in a leukemic patient treated with methotrexate.
description
1984 nî lūn-bûn
@nan
1984 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1984 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
name
Gene amplification in a leukemic patient treated with methotrexate.
@ast
Gene amplification in a leukemic patient treated with methotrexate.
@en
Gene amplification in a leukemic patient treated with methotrexate.
@nl
type
label
Gene amplification in a leukemic patient treated with methotrexate.
@ast
Gene amplification in a leukemic patient treated with methotrexate.
@en
Gene amplification in a leukemic patient treated with methotrexate.
@nl
prefLabel
Gene amplification in a leukemic patient treated with methotrexate.
@ast
Gene amplification in a leukemic patient treated with methotrexate.
@en
Gene amplification in a leukemic patient treated with methotrexate.
@nl
P2093
P356
P1476
Gene amplification in a leukemic patient treated with methotrexate.
@en
P2093
P356
10.1200/JCO.1984.2.1.2
P407
P577
1984-01-01T00:00:00Z