Repurposing cAMP-modulating medications to promote β-cell replication. - Wikidata - awgldk - TriplyDB

Repurposing cAMP-modulating medications to promote β-cell replication.

Repurposing cAMP-modulating medications to promote β-cell replication.

http://www.wikidata.org/entity/Q34265051

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Can exposure to environmental chemicals increase the risk of diabetes type 1 development?Ca2+ influx through L-type Ca2+ channels and Ca2+-induced Ca2+ release regulate cAMP accumulation and Epac1-dependent ERK 1/2 activation in INS-1 cells.Trimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in mice Critical role for adenosine receptor A2a in β-cell proliferation.IGFBP1 increases β-cell regeneration by promoting α- to β-cell transdifferentiation.A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform.Extracellular acidification stimulates GPR68 mediated IL-8 production in human pancreatic β cells.How to make insulin-producing pancreatic β cells for diabetes treatment.Genetic Disruption of Adenosine Kinase in Mouse Pancreatic β-Cells Protects Against High-Fat Diet-Induced Glucose Intolerance.Inhibition of TBK1/IKKε Promotes Regeneration of Pancreatic β-cells

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Repurposing cAMP-modulating medications to promote β-cell replication.

http://www.wikidata.org/entity/Q34265051

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Repurposing cAMP-modulating medications to promote β-cell replication.

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Repurposing cAMP-modulating medications to promote β-cell replication.

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Repurposing cAMP-modulating medications to promote β-cell replication.

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type

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Repurposing cAMP-modulating medications to promote β-cell replication.

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Repurposing cAMP-modulating medications to promote β-cell replication.

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Repurposing cAMP-modulating medications to promote β-cell replication.

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Repurposing cAMP-modulating medications to promote β-cell replication.

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Repurposing cAMP-modulating medications to promote β-cell replication.

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Repurposing cAMP-modulating medications to promote β-cell replication.

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Molecular Endocrinology

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Repurposing cAMP-modulating medications to promote β-cell replication

@en

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Anthony C Arvanites

http://www.w3.org/2001/XMLSchema#string

Gordon C Weir

http://www.w3.org/2001/XMLSchema#string

Jennifer Hollister-Lock

http://www.w3.org/2001/XMLSchema#string

Jennifer Hyoje Ryu

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Neali A Armstrong

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Nigam H Shah

http://www.w3.org/2001/XMLSchema#string

Sara A Sun

http://www.w3.org/2001/XMLSchema#string

Yen S Low

http://www.w3.org/2001/XMLSchema#string

Zhenshan Zhao

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P2860

Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes

Inhibition of insulin secretion via distinct signaling pathways in alpha2-adrenoceptor knockout mice.

Expression of alpha 2- and beta-adrenoceptor subtypes in human islets of Langerhans.

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Cyclic adenosine-3',5'-monophosphate stimulates islet B cell replication in neonatal rat pancreatic monolayer cultures

Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication

Phosphodiesterase 3 and 4 comprise the major cAMP metabolizing enzymes responsible for insulin secretion in INS-1 (832/13) cells and rat islets

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

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1682-1697

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scholarly article

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10.1210/ME.2014-1120

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10

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28

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Justin P. Annes

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2014-08-01T00:00:00Z

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264432158

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25083741

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4179632

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