The Rab-binding protein Noc2 is associated with insulin-containing secretory granules and is essential for pancreatic beta-cell exocytosis.
about
Clinical significance of a novel single nucleotide polymorphism in the 5' untranslated region of the Rabphillin-3A-Like gene in colorectal adenocarcinomaβ-Cell MicroRNAs: Small but PowerfulInfluence of miRNA in insulin signaling pathway and insulin resistance: micro-molecules with a major role in type-2 diabetesMicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cellsThe C2B domain of rabphilin directly interacts with SNAP-25 and regulates the docking step of dense core vesicle exocytosis in PC12 cellsPancreatic beta cells require NeuroD to achieve and maintain functional maturityRole of Rab GTPases in membrane traffic and cell physiologyCharacterization of Munc13-1 and insulin secretion during pancreatic development in rats.Small G proteins in islet beta-cell function.ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis.PI3K p110α/Akt signaling negatively regulates secretion of the intestinal peptide neurotensin through interference of granule transport.Insulin vesicle release: walk, kiss, pause ... then run.Immunohistochemical expression of rabphilin-3A-like (Noc2) in normal and tumor tissues of human endocrine pancreas.Synaptotagmins bind calcium to release insulin.The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells.Rab27 effectors, pleiotropic regulators in secretory pathways.Dynamin is functionally coupled to insulin granule exocytosis.Proteomics analysis of insulin secretory granules.Insulin regulates Rab3-Noc2 complex dissociation to promote GLUT4 translocation in rat adipocytes.Evidence that electrostatic interactions between vesicle-associated membrane protein 2 and acidic phospholipids may modulate the fusion of transport vesicles with the plasma membraneKinetics of Rab27a-dependent actions on vesicle docking and priming in pancreatic beta-cells.Alternative splicing in the first alpha-helical region of the Rab-binding domain of Rim regulates Rab3A binding activity: is Rim a Rab3 effector protein during evolution?Slp4-a/granuphilin-a interacts with syntaxin-2/3 in a Munc18-2-dependent manner.miR-124a expression contributes to the monophasic pattern of insulin secretion in islets from pregnant rats submitted to a low-protein diet.Transcriptional profiling reveals distinct classes of parathyroid tumors in PHPT.
P2860
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P2860
The Rab-binding protein Noc2 is associated with insulin-containing secretory granules and is essential for pancreatic beta-cell exocytosis.
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The Rab-binding protein Noc2 i ...... ncreatic beta-cell exocytosis.
@ast
The Rab-binding protein Noc2 i ...... ncreatic beta-cell exocytosis.
@en
The Rab-binding protein Noc2 i ...... ncreatic beta-cell exocytosis.
@nl
type
label
The Rab-binding protein Noc2 i ...... ncreatic beta-cell exocytosis.
@ast
The Rab-binding protein Noc2 i ...... ncreatic beta-cell exocytosis.
@en
The Rab-binding protein Noc2 i ...... ncreatic beta-cell exocytosis.
@nl
prefLabel
The Rab-binding protein Noc2 i ...... ncreatic beta-cell exocytosis.
@ast
The Rab-binding protein Noc2 i ...... ncreatic beta-cell exocytosis.
@en
The Rab-binding protein Noc2 i ...... ncreatic beta-cell exocytosis.
@nl
P2093
P356
P1476
The Rab-binding protein Noc2 i ...... ncreatic beta-cell exocytosis.
@en
P2093
Lee P Haynes
Robert D Burgoyne
Séverine Cheviet
P304
P356
10.1210/ME.2003-0300
P577
2003-10-30T00:00:00Z