Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice. - Wikidata - awgldk - TriplyDB

Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice.

Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice.

http://www.wikidata.org/entity/Q34275695

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Recent advances in mitochondrial research Myocardial creatine levels do not influence response to acute oxidative stress in isolated perfused heart Myocardial perfusion and oxygenation are impaired during stress in severe aortic stenosis and correlate with impaired energetics and subclinical left ventricular dysfunction Modular organization of cardiac energy metabolism: energy conversion, transfer and feedback regulation.Metabolic flux as a predictor of heart failure prognosis.Decreased creatine kinase is linked to diastolic dysfunction in rats with right heart failure induced by pulmonary artery hypertension Augmentation of Creatine in the Heart.Age-related changes of myocardial ATP supply and demand mechanisms.The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter.Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association.Unchanged mitochondrial organization and compartmentation of high-energy phosphates in creatine-deficient GAMT-/- mouse hearts.Mechanotransduction and Metabolism in Cardiomyocyte Microdomains.Normal cardiac function in mice with supraphysiological cardiac creatine levels Myocardial energetics in heart failure.Heart failure and loss of metabolic control Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research.Matrix revisited: mechanisms linking energy substrate metabolism to the function of the heart.Role of the phosphocreatine system on energetic homeostasis in skeletal and cardiac muscles.X-linked creatine transporter deficiency: clinical aspects and pathophysiology.Homoarginine in the renal and cardiovascular systems.Cellular bioenergetics of guanidinoacetic acid: the role of mitochondria.Advanced physiological roles of guanidinoacetic acid.Potential of creatine or phosphocreatine supplementation in cerebrovascular disease and in ischemic heart disease.Mitochondrial Therapies in Heart Failure.Metabolic remodelling in hypertrophied and failing myocardium: a review.The location of energetic compartments affects energetic communication in cardiomyocytes.Selecting heart failure patients for metabolic interventions.Creatine--a dispensable metabolite?Mitochondrial energetics and calcium coupling in the heart.Metabolic compartmentation in rainbow trout cardiomyocytes: coupling of hexokinase but not creatine kinase to mitochondrial respiration.Impaired ADP channeling to mitochondria and elevated reactive oxygen species in hypertensive hearts.The acute effect of beta-guanidinopropionic acid versus creatine or placebo in healthy men (ABC-Trial): A randomized controlled first-in-human trial.Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine.Guanidinoacetic acid versus creatine for improved brain and muscle creatine levels: a superiority pilot trial in healthy men.Cardiac effects of SGLT2 inhibitors: the sodium hypothesis.Decreased ATP production and myocardial contractile reserve in metabolic heart disease.The extended, dynamic mitochondrial reticulum in skeletal muscle and the creatine kinase (CK)/phosphocreatine (PCr) shuttle are working hand in hand for optimal energy provision.Creatine: a miserable life without it.Mitochondrial Calcium Increase Induced by RyR1 and IP3R Channel Activation After Membrane Depolarization Regulates Skeletal Muscle Metabolism.The creatine kinase system as a therapeutic target for myocardial ischaemia-reperfusion injury

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P2860

Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice.

http://www.wikidata.org/entity/Q34275695

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2013 nî lūn-bûn

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2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2013 թվականի հունվարին հրատարակված գիտական հոդված

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2013年の論文

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Living without creatine: uncha ...... on in creatine-deficient mice.

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Circulation Research

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Dana Dawson

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Debra J Medway

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P2860

Creatine and creatinine metabolism

The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity

Severely altered guanidino compound levels, disturbed body weight homeostasis and impaired fertility in a mouse model of guanidinoacetate N-methyltransferase (GAMT) deficiency

In vivo magnetic resonance spectroscopy of transgenic mouse models with altered high-energy phosphoryl transfer metabolism.

Evolution and physiological roles of phosphagen systems.

Creatine and creatine deficiency syndromes: biochemical and clinical aspects.

The metabolic burden of creatine synthesis.

Mitochondrial creatine kinase in human health and disease.

Impairment of energy metabolism in intact residual myocardium of rat hearts with chronic myocardial infarction.

Energy metabolism in heart failure.

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Keith M Channon

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23325497

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