The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration - Wikidata - awgldk - TriplyDB

The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration

The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration

http://www.wikidata.org/entity/Q34281402

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Neurodegeneration with brain iron accumulation: update on pathogenic mechanisms Retinal iron homeostasis in health and disease Iron dysregulation in Huntington's disease Animal models of age related macular degeneration Orally active multi-functional antioxidants are neuroprotective in a rat model of light-induced retinal damage Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration Drug-Based Lead Discovery: The Novel Ablative Antiretroviral Profile of Deferiprone in HIV-1-Infected Cells and in HIV-Infected Treatment-Naive Subjects of a Double-Blind, Placebo-Controlled, Randomized Exploratory Trial Dietary lactoferrin alleviates age-related lacrimal gland dysfunction in mice Deletion of hemojuvelin, an iron-regulatory protein, in mice results in abnormal angiogenesis and vasculogenesis in retina along with reactive gliosis.The oral iron chelator deferiprone protects against systemic iron overload-induced retinal degeneration in hepcidin knockout mice.Systemic administration of the antioxidant/iron chelator α-lipoic acid protects against light-induced photoreceptor degeneration in the mouse retina.A murine RP1 missense mutation causes protein mislocalization and slowly progressive photoreceptor degeneration Iron upregulates melanogenesis in cultured retinal pigment epithelial cells Iron increases APP translation and amyloid-beta production in the retina.Systemic administration of the iron chelator deferiprone protects against light-induced photoreceptor degeneration in the mouse retina An association between environmental factors and the IVS4+44C>A polymorphism of the DMT1 gene in age-related macular degeneration Prochelator BHAPI protects cells against paraquat-induced damage by ROS-triggered iron chelation Mice with hepcidin-resistant ferroportin accumulate iron in the retina.Lack of association between the c.544G>A polymorphism of the heme oxygenase-2 gene and age-related macular degeneration A boronate prochelator built on a triazole framework for peroxide-triggered tridentate metal binding Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity The Oral Iron Chelator Deferiprone Protects Against Retinal Degeneration Induced through Diverse Mechanisms.Metal chelator combined with permeability enhancer ameliorates oxidative stress-associated neurodegeneration in rat eyes with elevated intraocular pressure.Role of iron in ischemia-induced neurodegeneration: mechanisms and insights.Retinal abnormalities in β-thalassemia major.Melanosome-iron interactions within retinal pigment epithelium-derived cells.Conditional Müller Cell Ablation Leads to Retinal Iron Accumulation The Oral Iron Chelator Deferiprone Protects Against Retinal Degeneration Induced through Diverse Mechanisms Take Two Iron Chelators and Call Me in the Morning Intraperitoneal injection of (-)-Epigallocatechin-3-gallate protects against light-induced photoreceptor degeneration in the mouse retina.Identification of a novel neurotrophic factor from primary retinal Müller cells using stable isotope labeling by amino acids in cell culture (SILAC).Ironing out neurodegeneration: iron chelation for neuroprotection The hydrolytic susceptibility of prochelator BSIH in aqueous solutions.Iron chelator alleviates tubulointerstitial fibrosis in diabetic nephropathy rats by inhibiting the expression of tenascinC and other correlation factors.Iron promotes oxidative cell death caused by bisretinoids of retina.Ophthalmic Evaluation in Beta-Thalassemia.

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The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration

http://www.wikidata.org/entity/Q34281402

description

2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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The oral iron chelator deferip ...... d-induced retinal degeneration

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The oral iron chelator deferip ...... d-induced retinal degeneration

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The oral iron chelator deferip ...... d-induced retinal degeneration

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The oral iron chelator deferip ...... d-induced retinal degeneration

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The oral iron chelator deferip ...... d-induced retinal degeneration

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Investigative Ophthalmology & Visual Science

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The oral iron chelator deferip ...... d-induced retinal degeneration

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Arkady Lyubarsky

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Domenico Pratico

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Jared Iacovelli

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Jennifer Lee

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John Connelly

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Joshua L Dunaief

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Majda Hadziahmetovic

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Michael Spino

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Steven Grieco

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P2860

Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease

CCR3 is a target for age-related macular degeneration diagnosis and therapy

A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8

Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration

High concentration of zinc in sub-retinal pigment epithelial deposits

Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse

Functionally rodless mice: transgenic models for the investigation of cone function in retinal disease and therapy

Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice

Nanoparticle and iron chelators as a potential novel Alzheimer therapy.

Oxidative damage and protection of the RPE.

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10.1167/IOVS.10-6207

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