Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization. - Wikidata - awgldk - TriplyDB

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.

http://www.wikidata.org/entity/Q34284855

about

Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1 HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization A gp41 MPER-specific Llama VHH Requires a Hydrophobic CDR3 for Neutralization but not for Antigen Recognition Structural Basis of HCV Neutralization by Human Monoclonal Antibodies Resistant to Viral Neutralization Escape Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies Elicitation of HIV-1-neutralizing antibodies against the CD4-binding site.Neutralisation of HIV-1 cell-cell spread by human and llama antibodies.Molecular structures of trimeric HIV-1 Env in complex with small antibody derivatives.Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies.Recombinant monovalent llama-derived antibody fragments (VHH) to rotavirus VP6 protect neonatal gnotobiotic piglets against human rotavirus-induced diarrhea.Epitope mapping of M36, a human antibody domain with potent and broad HIV-1 inhibitory activity.Antigenic requirement for Gag in a vaccine that protects against high-dose mucosal challenge with simian immunodeficiency virus.Development of VHH antibodies against dengue virus type 2 NS1 and comparison with monoclonal antibodies for use in immunological diagnosis.Germlining of the HIV-1 broadly neutralizing antibody domain m36 Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas.Repeated Vaccination of Cows with HIV Env gp140 during Subsequent Pregnancies Elicits and Sustains an Enduring Strong Env-Binding and Neutralising Antibody Response.Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform.Effects of partially dismantling the CD4 binding site glycan fence of HIV-1 Envelope glycoprotein trimers on neutralizing antibody induction.Neutralizing antibodies to HIV-1 induced by immunization.Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice.CD4 binding site broadly neutralizing antibody selection of HIV-1 escape mutants.Expression of Human Immunodeficiency Virus Type 1 Neutralizing Antibody Fragments Using Human Vaginal Lactobacillus.The Glycosylphosphatidylinositol-Anchored Variable Region of Llama Heavy Chain-Only Antibody JM4 Efficiently Blocks both Cell-Free and T Cell-T Cell Transmission of Human Immunodeficiency Virus Type 1.Trimeric gp120-specific bovine monoclonal antibodies require cysteine and aromatic residues in CDRH3 for high affinity binding to HIV Env.Antibody-based candidate therapeutics against HIV-1: implications for virus eradication and vaccine design.Human immunodeficiency virus antibodies and the vaccine problem.The maturation of antibody technology for the HIV epidemic.Germline-targeting immunogens.Identification and specificity of broadly neutralizing antibodies against HIV Inhibition of HIV Virus by Neutralizing Vhh Attached to Dual Functional Liposomes Encapsulating Dapivirine.Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers.Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies.Decoupling competing surface binding kinetics and reconfiguration of receptor footprint for ultrasensitive stress assays.Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein E2 recognized by broadly neutralizing antibodies.Polyclonal antibodies for the detection of Trypanosoma cruzi circulating antigens.Single-Domain Antibodies As Therapeutics against Human Viral Diseases.Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows.The Hard Way towards an Antibody-Based HIV-1 Env Vaccine: Lessons from Other Viruses.Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation.

P2860

Q27322403-C96CD5BE-75F5-4650-BF32-10B45561AF40 Q27324184-674A0C3A-AA43-43F7-A6E2-E2FD56B24009 Q27676864-A6485E80-BEB5-4B32-8EAE-00EEB1AF463F Q27678252-A8AD79EC-CEC5-48D8-A886-9FB24D9A6D7A Q27679031-B5141FF0-0116-49D7-9151-753A0E409DEF Q28602877-7A8E3793-D172-4F4B-A6B5-6189E58AE7A8 Q34133551-81972CE8-753D-48F1-9EA7-D31B34A2AB1B Q34304203-558F89E2-E054-4800-AA6F-97B3E7FE9047 Q34522657-6561FD87-7697-42E3-833F-0E20AA970CB9 Q34594905-4042E949-E7FB-4C93-874D-889F422FD0DE Q34711833-4863FAFF-2E7C-4EDA-A0CF-DF8D83D75297 Q34776841-ABA06499-CA60-4392-A3D3-750B96532FFA Q35069151-371C144C-BC58-4973-A842-879EEAB10429 Q35153910-B62951F5-2B4A-41C9-8593-E6FE390D105E Q35171173-0866599C-A0D3-4B8E-A10A-9BCF842AD0ED Q35677620-807FBEDC-3ADC-4F70-86E8-396222355FC0 Q36051764-0CC1B2EC-42AA-4796-805D-6924475D7F99 Q36214456-0F40BCE5-A7F6-4F65-8B5D-4D542F57FBFF Q36303368-03BECB4B-D6D3-431C-A1BB-C77ED39F7A4A Q36603515-32E3A2E0-2C6C-4BB0-A6AF-4F0ACFC629B3 Q36627503-72121636-A0B8-49D6-9104-A21FB70517FE Q36810796-B442A56A-225E-461A-ACB5-5FE72F7A1C4A Q37346068-03D893A3-1400-4A36-BD48-746F69117017 Q37415455-86DF6C31-6D81-4C32-B329-053E0E7D5567 Q37742119-89578599-9BAD-4BED-AA45-EC4102A835AB Q38072056-A98646D0-D2F1-4BB3-B622-AAA10E50D90A Q38192126-6F714F4F-C761-408B-8198-F2E27ABFB44F Q38209477-26B413E9-5616-4330-8A8D-3E9AA6D98C92 Q38764547-497970B0-ECFC-4153-81D2-BAE35665C915 Q39108796-ADB161B2-8E02-4B2D-AF51-4842B55B019D Q39575923-B227A3C4-26E4-406C-AAE9-DA5E0524C7CF Q40076041-1EF6AE27-0AE9-4DC7-85F9-FA44A2E96170 Q40568483-A9545742-7F56-481D-8ECF-56712B91A787 Q41048768-61E6DDC8-ACDB-44D1-8593-3E96C0230992 Q41619358-904F6F50-0054-4382-910C-44238952D6F3 Q47105957-C6A155F0-9D44-47AB-8290-711C71AA8718 Q47554821-D0AC7F25-6615-4DFF-B45A-CE4CF33642BE Q47700206-42EE311E-65D2-4571-9003-E8821970C96E Q52584646-2B653DA3-4B78-452A-AF0A-7B29E9A879C9 Q53689028-5FF461FE-ECFB-4E80-B580-8F74BB88C5B0

P2860

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.

http://www.wikidata.org/entity/Q34284855

description

2012 nî lūn-bûn

@nan

2012 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.

@ast

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.

@en

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.

@nl

type

label

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.

@ast

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.

@en

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.

@nl

prefLabel

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.

@ast

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.

@en

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.

@nl

P1433

Q34284855-E4CED538-2280-451A-869A-9F063861272E

P1476

Q34284855-66E91C2A-EE87-4BF2-8158-CDF5B6C3AA76

P2093

Q34284855-144B2D43-7F10-40C7-B360-0734048083DE

Q34284855-26C5ABED-DD44-4480-9F95-70C530AD17FF

Q34284855-390E49F8-7C38-4BA8-BD3F-2B71ECE9F506

Q34284855-4958FBE3-F35F-4D5E-941E-BC38DF4AB11D

Q34284855-4F6BFA20-F24A-4972-A113-BE61B92DDB88

Q34284855-6E62948B-C66E-4DD0-9DA2-A1A5AA6E5DBE

Q34284855-948E62F5-59E2-4F62-ADB3-B6F99DA010E3

Q34284855-BA8235FC-919D-4C1C-9B2D-82363CF4FBA7

Q34284855-DBBCCDE4-474C-4059-806F-53BE9BA7BAEC

Q34284855-DDDC76A3-263B-435F-9950-39F32CECECB0

P2860

Q34284855-003F442F-317A-46A5-9DB2-B3784D428393

Q34284855-0BC9F172-E058-4455-9583-63A89ABBC3C1

Q34284855-126EEB19-3651-4A75-80D2-3321EC29C404

Q34284855-1719471A-A2AD-462E-8CB6-85F551E2DAC0

Q34284855-1B44E8F8-D11C-4795-B5E2-7C6423D56E6F

Q34284855-1D8D684C-257D-49E7-9176-E81961C3307D

Q34284855-24D5347D-A06B-4739-9652-99CBBC0D8943

Q34284855-2B536F4C-C81C-400C-8466-78BA2130210F

Q34284855-2CCFDEBB-567F-4ABC-ACC0-D926BDA54E55

Q34284855-2F1D9E8C-2F3A-48B1-B13D-FB94038E11B6

P304

Q34284855-7A05AFF9-60D9-4482-9432-0CA65983BDB8

P31

Q34284855-96CF09F3-5EF2-4AFC-961F-9FB7FB1584A5

P356

Q34284855-A6AF98ED-22A6-4549-86BB-AC3F9A24209D

P407

Q34284855-21227647-DA98-4958-BFA5-2EAABF72664B

P433

Q34284855-92E844A9-2464-4A81-B34B-42F2E771E5FE

P478

Q34284855-45C53489-AEAC-4BB7-AE90-24E0C76D856C

P577

Q34284855-1574DD5A-9004-4343-A359-F25B18007448

P5875

Q34284855-A7F427C2-80C7-489A-9124-3D542F3A1B66

P698

Q34284855-9F7B264E-7E7A-4384-8904-9971E56B1C15

P921

Q34284855-424379A3-7945-4886-8748-2446C03744AA

Q34284855-4BA90D18-E025-4EBF-AA5E-2E5DD422A335

P932

Q34284855-8D8C6D42-F396-4019-888D-5E652F707DE8

P356

P1433

Journal of Experimental Medicine

P1476

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.

@en

P2093

Anna Forsman Quigley

http://www.w3.org/2001/XMLSchema#string

Bianca Bulmer-Thomas

http://www.w3.org/2001/XMLSchema#string

Carolyn J Edwards

http://www.w3.org/2001/XMLSchema#string

Daniella Mortier

http://www.w3.org/2001/XMLSchema#string

David Davis

http://www.w3.org/2001/XMLSchema#string

Laura E McCoy

http://www.w3.org/2001/XMLSchema#string

Lucy Rutten

http://www.w3.org/2001/XMLSchema#string

Michael S Seaman

http://www.w3.org/2001/XMLSchema#string

Nika M Strokappe

http://www.w3.org/2001/XMLSchema#string

Nikita Chander

http://www.w3.org/2001/XMLSchema#string

P2860

A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals

Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women

Increasing the potency and breadth of an HIV antibody by using structure-based rational design

Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1

An anti-HIV-1 V3 loop antibody fully protects cross-clade and elicits T-cell immunity in macaques mucosally challenged with an R5 clade C SHIV

Crystal Structure of the Neutralizing Llama VHH D7 and Its Mode of HIV-1 gp120 Interaction

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

Naturally occurring antibodies devoid of light chains

The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on

P304

1091-1103

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.20112655

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

209

http://www.w3.org/2001/XMLSchema#string

P577

2012-05-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

225069148

http://www.w3.org/2001/XMLSchema#string

P698

22641382

http://www.w3.org/2001/XMLSchema#string

P921

P932

3371729

http://www.w3.org/2001/XMLSchema#string