Regulated secretion of acid sphingomyelinase: implications for selectivity of ceramide formation.
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Caspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomesTrafficking and Functions of Bioactive Sphingolipids: Lessons from Cells and Model MembranesInhibition of acid sphingomyelinase by tricyclic antidepressants and analogonsThe structure and catalytic mechanism of human sphingomyelin phosphodiesterase like 3a--an acid sphingomyelinase homologue with a novel nucleotide hydrolase activitySphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is a novel nucleotide phosphodiesterase regulated by cholesterol in human macrophagesEvaluation of the role of secretory sphingomyelinase and bioactive sphingolipids as biomarkers in hemophagocytic lymphohistiocytosisIdentification and biochemical characterization of an acid sphingomyelinase-like protein from the bacterial plant pathogen Ralstonia solanacearum that hydrolyzes ATP to AMP but not sphingomyelin to ceramideHyperresponsiveness of mice deficient in plasma-secreted sphingomyelinase reveals its pivotal role in early phase of host responseA potent sphingomyelinase inhibitor from Cordyceps mycelia contributes its cytoprotective effect against oxidative stress in macrophagesDefining a role for acid sphingomyelinase in the p38/interleukin-6 pathway.Structural characterization and antioxidative activity of low-molecular-weights beta-1,3-glucan from the residue of extracted Ganoderma lucidum fruiting bodiesA novel mechanism of lysosomal acid sphingomyelinase maturation: requirement for carboxyl-terminal proteolytic processing.Regulation of CC ligand 5/RANTES by acid sphingomyelinase and acid ceramidase.Ceramide synthase-dependent ceramide generation and programmed cell death: involvement of salvage pathway in regulating postmitochondrial events.Alternative splicing of SMPD1 in human sepsis.Ceramide kinase regulates the production of tumor necrosis factor α (TNFα) via inhibition of TNFα-converting enzyme.Targeting (cellular) lysosomal acid ceramidase by B13: design, synthesis and evaluation of novel DMG-B13 ester prodrugs.Safety study of adeno-associated virus serotype 2-mediated human acid sphingomyelinase expression in the nonhuman primate brain.Evidence for coordination of lysosomal (ASMase) and plasma membrane (NSMase2) forms of sphingomyelinase from mutant mice.Gastric bypass surgery reduces plasma ceramide subspecies and improves insulin sensitivity in severely obese patients.Interferon-Beta Increases Plasma Ceramides of Specific Chain Length in Multiple Sclerosis Patients, Unlike Fingolimod or Natalizumab.Acid sphingomyelinase in macrophage biology.The role of sphingolipids in respiratory disease.The role of sphingolipids in drug metabolism and transport.Platelet-derived sphingosine-1-phosphate and inflammation: from basic mechanisms to clinical implications.Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury.Differential regulation of acid sphingomyelinase in macrophages stimulated with oxidized low-density lipoprotein (LDL) and oxidized LDL immune complexes: role in phagocytosis and cytokine release.Sphingolipid abnormalities in cancer multidrug resistance: Chicken or egg?Acid sphingomyelinase promotes endothelial stress response in systemic inflammation and sepsis.A new twist to the emerging functions of ceramides in cancer: novel role for platelet acid sphingomyelinase in cancer metastasis.ALTERED BLOOD SPHINGOLIPIDOMICS AND ELEVATED PLASMA INFLAMMATORY CYTOKINES IN COMBAT VETERANS WITH POST-TRAUMATIC STRESS DISORDERTricyclic Antidepressants Promote Ceramide Accumulation to Regulate Collagen Production in Human Hepatic Stellate Cells.Lactosylceramide interacts with and activates cytosolic phospholipase A2α.Alteration of sphingolipid metabolism as a putative mechanism underlying LPS-induced BBB disruption.Fingolimod attenuates ceramide-induced blood-brain barrier dysfunction in multiple sclerosis by targeting reactive astrocytes.Identification of an acid sphingomyelinase ceramide kinase pathway in the regulation of the chemokine CCL5.
P2860
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P2860
Regulated secretion of acid sphingomyelinase: implications for selectivity of ceramide formation.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Regulated secretion of acid sp ...... ctivity of ceramide formation.
@ast
Regulated secretion of acid sp ...... ctivity of ceramide formation.
@en
Regulated secretion of acid sp ...... ctivity of ceramide formation.
@nl
type
label
Regulated secretion of acid sp ...... ctivity of ceramide formation.
@ast
Regulated secretion of acid sp ...... ctivity of ceramide formation.
@en
Regulated secretion of acid sp ...... ctivity of ceramide formation.
@nl
prefLabel
Regulated secretion of acid sp ...... ctivity of ceramide formation.
@ast
Regulated secretion of acid sp ...... ctivity of ceramide formation.
@en
Regulated secretion of acid sp ...... ctivity of ceramide formation.
@nl
P2093
P2860
P50
P356
P1476
Regulated secretion of acid sp ...... ectivity of ceramide formation
@en
P2093
Chiara Luberto
David M Perry
Fabio Simbari
Jolanta Idkowiak-Baldys
Patrick Roddy
Russell W Jenkins
P2860
P304
35706-35718
P356
10.1074/JBC.M110.125609
P407
P577
2010-08-31T00:00:00Z