about
Internalization of cationic peptides: the road less (or more?) traveledCorrelation of elevated level of blood midkine with poor prognostic factors of human neuroblastomasS100C/A11 is a key mediator of Ca(2+)-induced growth inhibition of human epidermal keratinocytesPancreatic cancerStructure and function of midkine as the basis of its pharmacological effectsStructure-function analysis of full-length midkine reveals novel residues important for heparin binding and zebrafish embryogenesisSuppression of tumor growth and angiogenesis by a specific antagonist of the cell-surface expressed nucleolinMet-Independent Hepatocyte Growth Factor-mediated regulation of cell adhesion in human prostate cancer cells.Nuclear translocation of urokinase-type plasminogen activatorTranscriptome profiling of the tubular porcine conceptus identifies the differential regulation of growth and developmentally associated genes.Construction of a fusion protein expression vector MK-EGFP and its subcellular localization in different carcinoma cell lines.Structure-function analysis of nucleolin and ErbB receptors interactions.DNA damage-induced translocation of S100A11 into the nucleus regulates cell proliferationSurface expressed nucleolin is constantly induced in tumor cells to mediate calcium-dependent ligand internalization.The synthetic peptide P111-136 derived from the C-terminal domain of heparin affin regulatory peptide inhibits tumour growth of prostate cancer PC-3 cells.Synthesis and investigation of a radioiodinated F3 peptide analog as a SPECT tumor imaging radioligandTargeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell typePigment epithelium-derived factor (PEDF) interacts with transportin SR2, and active nuclear import is facilitated by a novel nuclear localization motif.Beyond endocytosis: LRP function in cell migration, proliferation and vascular permeability.Premature ligand-receptor interaction during biosynthesis limits the production of growth factor midkine and its receptor LDL receptor-related protein 1A novel post-translational modification of nucleolin, SUMOylation at Lys-294, mediates arsenite-induced cell death by regulating gadd45α mRNA stability.New light on a long-known protein family.Midkine: a promising molecule for drug development to treat diseases of the central nervous systemCell surface nucleolin on developing muscle is a potential ligand for the axonal receptor protein tyrosine phosphatase-sigmaPleiotrophin expression and role in physiological angiogenesis in vivo: potential involvement of nucleolinMidkine, a heparin-binding cytokine with multiple roles in development, repair and diseases.Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vesselsMidkine, a cytokine that inhibits HIV infection by binding to the cell surface expressed nucleolin.Nucleolin antagonist triggers autophagic cell death in human glioblastoma primary cells and decreased in vivo tumor growth in orthotopic brain tumor model.Interactions of lactoferrin with cells involved in immune function.Antagonizing midkine accelerates fracture healing in mice by enhanced bone formation in the fracture callusMidkine promotes selective expansion of the nephrogenic mesenchyme during kidney organogenesisMidkine translocated to nucleoli and involved in carcinogenesis.Midkine secretion protects Hep3B cells from cadmium induced cellular damage.Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancerMidkine: a novel prognostic biomarker for cancer.Proapoptotic peptide-mediated cancer therapy targeted to cell surface p32.Therapeutic potential of midkine in cardiovascular disease.Lactoferrin, a key molecule in immune and inflammatory processes.Midkine in the pathology of cancer, neural disease, and inflammation.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Nuclear targeting by the growth factor midkine.
@ast
Nuclear targeting by the growth factor midkine.
@en
Nuclear targeting by the growth factor midkine.
@nl
type
label
Nuclear targeting by the growth factor midkine.
@ast
Nuclear targeting by the growth factor midkine.
@en
Nuclear targeting by the growth factor midkine.
@nl
prefLabel
Nuclear targeting by the growth factor midkine.
@ast
Nuclear targeting by the growth factor midkine.
@en
Nuclear targeting by the growth factor midkine.
@nl
P2093
P2860
P1476
Nuclear targeting by the growth factor midkine.
@en
P2093
Hidehiko Saito
Kenji Kadomatsu
Lynn M McCormick
Makoto Hirai
Takashi Muramatsu
Tatsuya Inui
Terutoshi Kimura
Yoshihisa Shibata
P2860
P304
P356
10.1128/MCB.22.19.6788-6796.2002
P407
P577
2002-10-01T00:00:00Z