Fcγ receptors are required for NF-κB signaling, microglial activation and dopaminergic neurodegeneration in an AAV-synuclein mouse model of Parkinson's disease.
about
Glia and alpha-synuclein in neurodegeneration: A complex interactionM1 and M2 immune activation in Parkinson's Disease: Foe and ally?Immunomodulators as Therapeutic Agents in Mitigating the Progression of Parkinson's DiseaseRecombinant Adeno-Associated Virus-mediated rescue of function in a mouse model of Dopamine Transporter Deficiency Syndrome.rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration.Involvement of the Fc gamma receptor in a chronic N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of dopaminergic loss.Role of α-synuclein in inducing innate and adaptive immunity in Parkinson disease.Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson Disease.Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling.microRNA-155 Regulates Alpha-Synuclein-Induced Inflammatory Responses in Models of Parkinson Disease.RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells.Antibody uptake into neurons occurs primarily via clathrin-dependent Fcγ receptor endocytosis and is a prerequisite for acute tau protein clearance.RNA Interference of Human α-Synuclein in Mouse.AAV1/2-induced overexpression of A53T-α-synuclein in the substantia nigra results in degeneration of the nigrostriatal system with Lewy-like pathology and motor impairment: a new mouse model for Parkinson's disease.The role of glia in α-synucleinopathies.The role of innate and adaptive immunity in Parkinson's disease.New roles for Fc receptors in neurodegeneration-the impact on Immunotherapy for Alzheimer's Disease.How can rAAV-α-synuclein and the fibril α-synuclein models advance our understanding of Parkinson's disease?Prelysosomal Compartments in the Unconventional Secretion of Amyloidogenic Seeds.RNF11 modulates microglia activation through NF-κB signalling cascade.Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration.The gamma chain subunit of Fc receptors is required for alpha-synuclein-induced pro-inflammatory signaling in microglia.MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration.Nurr1:RXRα heterodimer activation as monotherapy for Parkinson's disease.Peripheral monocyte entry is required for alpha-Synuclein induced inflammation and Neurodegeneration in a model of Parkinson disease.6-Hydroxydopamine as a tool to understand adaptive immune system-induced dopamine neurodegeneration in Parkinson's disease.Bimolecular Fluorescence Complementation of Alpha-synuclein Demonstrates its Oligomerization with Dopaminergic Phenotype in Mice.The Challenge of the Pathogenesis of Parkinson's Disease: Is Autoimmunity the Culprit?
P2860
Q26851153-33DC6740-2C3B-47FA-B7FA-32A7E32F6599Q27024667-7B74A09A-DE69-41EC-9ABF-DCE5BAA76215Q28079187-F71306C4-2833-4F0D-A0E8-6056161ADD5AQ33573088-C6020B92-E2AB-4858-AF33-69E1FF3F20A0Q34465572-9F5EE928-9C8F-4BF9-A824-C7AFF4B4662DQ35309412-57F12941-C90B-4758-B46F-9F8E8E5F265CQ35510197-95DECC2E-A44B-43D3-9E53-4F5D345B32ECQ35808359-9D6D03E6-6C40-458D-BB79-E7A528A11F9EQ36156573-21868299-064D-42BB-80CB-A5218CBA7E80Q36610305-C22C566A-D3AE-4DBF-97AA-C717C95356CDQ36773965-5679F530-BBB0-496B-A5DB-5DB9FDD2C658Q37368709-588FC1DE-1E6E-4FD0-84C4-A9D608BC9EB6Q37614503-1D3E25D6-CC31-4FAB-9074-72A75AEF551AQ37618665-129BDA00-8E56-4A8D-9AA6-DB33D4C75DC9Q38039880-871E802E-DBC6-4FCD-B655-52804A813074Q38166155-7CBAE950-503E-41A3-BA7B-7460128563ECQ38246262-03B39BE4-3588-42A6-ABC9-B51B9062FD94Q38790881-BED80A84-8B56-48DA-B977-AD6E40139B41Q39104462-226E7B6F-2555-4FCA-A546-BF142F124FC1Q39279441-6F0EFD96-572A-4448-A5A1-104CEE1A158AQ40768273-758BFD9D-214A-46B4-9045-0459A69939DCQ41761790-855D63C0-A2F4-40AE-A971-28381BD0FB05Q41894807-0DB8B574-CDBC-453A-986D-34FA1D93DD5FQ42291314-163C23A2-B0BF-4380-96D0-C6A4C9D07337Q47575506-DE9CB101-F6A5-4C87-931E-0E1E85A2EE47Q48077401-588102B6-7269-466A-8E72-E45F8B46ADC5Q50056490-7C35E907-B6BA-4F92-AF66-C53E3A38DDE2Q57490878-39A32658-1B9D-4033-AA74-49446C3E5B51
P2860
Fcγ receptors are required for NF-κB signaling, microglial activation and dopaminergic neurodegeneration in an AAV-synuclein mouse model of Parkinson's disease.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Fcγ receptors are required for ...... model of Parkinson's disease.
@ast
Fcγ receptors are required for ...... model of Parkinson's disease.
@en
Fcγ receptors are required for ...... model of Parkinson's disease.
@nl
type
label
Fcγ receptors are required for ...... model of Parkinson's disease.
@ast
Fcγ receptors are required for ...... model of Parkinson's disease.
@en
Fcγ receptors are required for ...... model of Parkinson's disease.
@nl
prefLabel
Fcγ receptors are required for ...... model of Parkinson's disease.
@ast
Fcγ receptors are required for ...... model of Parkinson's disease.
@en
Fcγ receptors are required for ...... model of Parkinson's disease.
@nl
P2860
P921
P356
P1476
Fcγ receptors are required for ...... e model of Parkinson's disease
@en
P2093
Shaji Theodore
P2860
P2888
P356
10.1186/1750-1326-5-42
P577
2010-10-26T00:00:00Z
P5875
P6179
1019297874