Glutathione metabolism in the lung: inhibition of its synthesis leads to lamellar body and mitochondrial defects
about
N-acetylcysteine in COPD: why, how, and when?Glutathione deficiency leads to mitochondrial damage in brainGlutathione regulates activation-dependent DNA synthesis in highly purified normal human T lymphocytes stimulated via the CD2 and CD3 antigensAugmentation of glutathione in the fluid lining the epithelium of the lower respiratory tract by directly administering glutathione aerosol.Cysteine and glutathione concentrations in plasma and bronchoalveolar lavage fluid after treatment with N-acetylcysteine.High-affinity transport of glutathione is part of a multicomponent system essential for mitochondrial functionImpaired uptake of glutathione by hepatic mitochondria from chronic ethanol-fed rats. Tracer kinetic studies in vitro and in vivo and susceptibility to oxidant stressEffect of chronic ethanol feeding on glutathione and functional integrity of mitochondria in periportal and perivenous rat hepatocytes.Glutathione is required for intestinal function.Glutathione ester prevents buthionine sulfoximine-induced cataracts and lens epithelial cell damage.Glutathione ester delays the onset of scurvy in ascorbate-deficient guinea pigs.Ascorbic acid prevents oxidative stress in glutathione-deficient mice: effects on lung type 2 cell lamellar bodies, lung surfactant, and skeletal muscle.CFTR activity and mitochondrial function.Glutathione: overview of its protective roles, measurement, and biosynthesisGlutathione deficiency increases hepatic ascorbic acid synthesis in adult mice.Glutathione deficiency decreases tissue ascorbate levels in newborn rats: ascorbate spares glutathione and protects.Inhibition of glutathione synthesis in the newborn rat: a model for endogenously produced oxidative stress.Characterization of mitochondrial function in cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function.Cytotoxicity and apoptosis induction by nanoscale talc particles from two different geographical regions in human lung epithelial cells.Differential induction of NF-kappaB activity and neural cell death by antidepressants in vitro.Effect of acute ozone exposure on the lung metabolomes of obese and lean mice.Transforming growth factor-beta1 is a potent inhibitor of glutathione synthesis in the lung epithelial cell line A549: transcriptional effect on the GSH rate-limiting enzyme gamma-glutamylcysteine synthetase.Heterogeneity of clara cell glutathione. A possible basis for differences in cellular responses to pulmonary cytotoxicants.Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma.Sulfur amino acid metabolism in hepatobiliary disorders.Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia.Depletion of pulmonary glutathione using diethylmaleic acid accelerates the development of oxygen-induced lung injury in term and preterm guinea-pig neonates.Dose-dependent genotoxicity of copper oxide nanoparticles stimulated by reactive oxygen species in human lung epithelial cells.Lipid peroxidation, glutathione levels and changes in glutathione-related enzyme activities in streptozotocin-induced diabetic rats.Effect of orally administered glutathione on glutathione levels in some organs of rats: role of specific transporters.Evidence that the rat hepatic mitochondrial carrier is distinct from the sinusoidal and canalicular transporters for reduced glutathione. Expression studies in Xenopus laevis oocytes.Subcellular compartmentalization of glutathione: correlations with parameters of oxidative stress related to genotoxicity.
P2860
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P2860
Glutathione metabolism in the lung: inhibition of its synthesis leads to lamellar body and mitochondrial defects
description
1989 nî lūn-bûn
@nan
1989 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
name
Glutathione metabolism in the ...... body and mitochondrial defects
@ast
Glutathione metabolism in the ...... body and mitochondrial defects
@en
Glutathione metabolism in the ...... body and mitochondrial defects
@nl
type
label
Glutathione metabolism in the ...... body and mitochondrial defects
@ast
Glutathione metabolism in the ...... body and mitochondrial defects
@en
Glutathione metabolism in the ...... body and mitochondrial defects
@nl
prefLabel
Glutathione metabolism in the ...... body and mitochondrial defects
@ast
Glutathione metabolism in the ...... body and mitochondrial defects
@en
Glutathione metabolism in the ...... body and mitochondrial defects
@nl
P2093
P2860
P356
P1476
Glutathione metabolism in the ...... body and mitochondrial defects
@en
P2093
P2860
P304
P356
10.1073/PNAS.86.14.5296
P407
P577
1989-07-01T00:00:00Z