Functional inhibition of endogenously produced urokinase decreases cell proliferation in a human melanoma cell line.
about
Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factorThe receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexesUrokinase receptor is associated with the components of the JAK1/STAT1 signaling pathway and leads to activation of this pathway upon receptor clustering in the human kidney epithelial tumor cell line TCL-598Cancer treatment with inhibitors of urokinase-type plasminogen activator and plasmin.Microvillar cell surface as a natural defense system against xenobiotics: a new interpretation of multidrug resistance.Molecular and functional interdependence of the urokinase-type plasminogen activator system with integrins.Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasisA labile repressor acts through the NFkB-like binding sites of the human urokinase gene.Oestradiol regulation of the components of the plasminogen-plasmin system in MDA-MB-231 human breast cancer cells stably expressing the oestrogen receptor.Prostate cancer cell-derived urokinase-type plasminogen activator contributes to intraosseous tumor growth and bone turnover.Fibroblast growth factors in normal and malignant melanocytes.The Ca2(+)-binding glycoprotein SPARC modulates cell cycle progression in bovine aortic endothelial cells.Modulators of the urokinase-type plasminogen activation system for cancer.Urokinase receptor orchestrates the plasminogen system in airway epithelial cell function.Molecular profiling of functional interactions between pre-osteoblastic and breast carcinoma cells.Urokinase signaling through its receptor protects against anoikis by increasing BCL-xL expression levels.Application of molecular modeling to urokinase inhibitors development.Stable expression of antisense urokinase mRNA inhibits the proliferation and invasion of human hepatocellular carcinoma cells.Gene response of human skin fibroblasts to urokinase- and tissue-type plasminogen activators.Urokinase-type plasminogen activator (uPA) and its receptor (CD87): a new target in tumor invasion and metastasis.Urokinase induces proliferation of human ovarian cancer cells: characterization of structural elements required for growth factor function.Recombinant soluble urokinase receptor as a scavenger for urokinase-type plasminogen activator (uPA). Inhibition of proliferation and invasion of human ovarian cancer cells.Phosphorylation of human pro-urokinase on Ser138/303 impairs its receptor-dependent ability to promote myelomonocytic adherence and motility.Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents.Proteases in cutaneous melanoma
P2860
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P2860
Functional inhibition of endogenously produced urokinase decreases cell proliferation in a human melanoma cell line.
description
1989 nî lūn-bûn
@nan
1989 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Functional inhibition of endog ...... in a human melanoma cell line.
@ast
Functional inhibition of endog ...... in a human melanoma cell line.
@en
Functional inhibition of endog ...... in a human melanoma cell line.
@nl
type
label
Functional inhibition of endog ...... in a human melanoma cell line.
@ast
Functional inhibition of endog ...... in a human melanoma cell line.
@en
Functional inhibition of endog ...... in a human melanoma cell line.
@nl
prefLabel
Functional inhibition of endog ...... in a human melanoma cell line.
@ast
Functional inhibition of endog ...... in a human melanoma cell line.
@en
Functional inhibition of endog ...... in a human melanoma cell line.
@nl
P2093
P2860
P356
P1476
Functional inhibition of endog ...... in a human melanoma cell line.
@en
P2093
Kirchheimer JC
P2860
P304
P356
10.1073/PNAS.86.14.5424
P407
P50
P577
1989-07-01T00:00:00Z