Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma.
about
Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasmDNA methylation-associated inactivation of TGFbeta-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancersLoss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis.RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD.The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis.Rare allelic imbalances, but no mutations of the PRDX1 gene in human hepatocellular carcinomasAltered placental DNA methylation patterns associated with maternal smoking: current perspectivesThe Cables gene on chromosome 18q is silenced by promoter hypermethylation and allelic loss in human colorectal cancer.DNA methylation of RUNX3 in papillary thyroid cancer.Targeting of RUNX3 by miR-130a and miR-495 cooperatively increases cell proliferation and tumor angiogenesis in gastric cancer cells.Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation.Loss of Runt-related transcription factor 3 induces resistance to 5-fluorouracil and cisplatin in hepatocellular carcinoma.Downregulation of the RUNX3 gene by promoter hypermethylation and hemizygous deletion in breast cancer.Placental DNA methylation alterations associated with maternal tobacco smoking at the RUNX3 gene are also associated with gestational age.Truncated forms of RUNX3 Unlike Full Length Protein Alter Cell Proliferation in a TGF-β Context Dependent Manner.Epigenetic inactivation of RUNX3 in colorectal cancer.Loss of RUNX3 is significantly associated with advanced tumor grade and stage in endometrial cancers.
P2860
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P2860
Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma.
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma.
@ast
Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma.
@en
Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma.
@nl
type
label
Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma.
@ast
Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma.
@en
Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma.
@nl
prefLabel
Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma.
@ast
Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma.
@en
Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma.
@nl
P2860
P1476
Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma.
@en
P2093
Wei-Wen Liu
Wen-Hua Xiao
P2860
P304
P407
P577
2004-02-01T00:00:00Z