Visualizing the site and dynamics of IgG salvage by the MHC class I-related receptor, FcRn.
about
Neonatal Fc receptor mediates internalization of Fc in transfected human endothelial cellsFc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeuticsCross-presentation of IgG-containing immune complexesPharmacokinetic models for FcRn-mediated IgG dispositionFc-fusion technology and recombinant FVIII and FIX in the management of the hemophiliasUnraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based TherapeuticsTrafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier.Targeting FcRn for the modulation of antibody dynamicsThe neonatal Fc receptor, FcRn, as a target for drug delivery and therapyFrom sorting endosomes to exocytosis: association of Rab4 and Rab11 GTPases with the Fc receptor, FcRn, during recycling.Elucidation of intracellular recycling pathways leading to exocytosis of the Fc receptor, FcRn, by using multifocal plane microscopy.High accuracy 3D quantum dot tracking with multifocal plane microscopy for the study of fast intracellular dynamics in live cells.Analyses of the recycling receptor, FcRn, in live cells reveal novel pathways for lysosomal delivery.Using multifocal plane microscopy to reveal novel trafficking processes in the recycling pathway.The effect of pH dependence of antibody-antigen interactions on subcellular trafficking dynamics.Use of Fc-Engineered Antibodies as Clearing Agents to Increase Contrast During PET.Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level.Simultaneous imaging of different focal planes in fluorescence microscopy for the study of cellular dynamics in three dimensions.Impact of SPR biosensor assay configuration on antibody: Neonatal Fc receptor binding data.Quantitative cumulative biodistribution of antibodies in mice: effect of modulating binding affinity to the neonatal Fc receptorContribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal StudiesTargeting FcRn for therapy: from live cell imaging to in vivo studies in mice.Engineered clearing agents for the selective depletion of antigen-specific antibodiesAn intracellular traffic jam: Fc receptor-mediated transport of immunoglobulin GStructure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor.Comparison of FcRn- and pIgR-mediated transport in MDCK cells by fluorescence confocal microscopy.Extending half-life by indirect targeting of the neonatal Fc receptor (FcRn) using a minimal albumin binding domain.Regulation of immune responses by the neonatal fc receptor and its therapeutic implicationsRobust expression of the human neonatal Fc receptor in a truncated soluble form and as a full-length membrane-bound protein in fusion with eGFPLigand valency affects transcytosis, recycling and intracellular trafficking mediated by the neonatal Fc receptorDivergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies.A generic approach to engineer antibody pH-switches using combinatorial histidine scanning libraries and yeast displayClaudin-4 undergoes age-dependent change in cellular localization on pig jejunal villous epithelial cells, independent of bacterial colonization.Intracellular neutralization of viral infection in polarized epithelial cells by neonatal Fc receptor (FcRn)-mediated IgG transport.Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics.Evidence that FcRn mediates the transplacental passage of maternal IgE in the form of IgG anti-IgE/IgE immune complexes.A Fab-Selective Immunoglobulin-Binding Domain from Streptococcal Protein G with Improved Half-Life Extension Properties.Improved tumor imaging and therapy via i.v. IgG-mediated time-sequential modulation of neonatal Fc receptor.Fc receptors and their role in immune regulation and autoimmunity.Localization of neonatal Fc receptor for IgG in aggregated lymphoid nodules area in abomasum of Bactrian camels (Camelus bactrianus) of different ages
P2860
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P2860
Visualizing the site and dynamics of IgG salvage by the MHC class I-related receptor, FcRn.
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Visualizing the site and dynam ...... lass I-related receptor, FcRn.
@ast
Visualizing the site and dynam ...... lass I-related receptor, FcRn.
@en
Visualizing the site and dynam ...... lass I-related receptor, FcRn.
@nl
type
label
Visualizing the site and dynam ...... lass I-related receptor, FcRn.
@ast
Visualizing the site and dynam ...... lass I-related receptor, FcRn.
@en
Visualizing the site and dynam ...... lass I-related receptor, FcRn.
@nl
prefLabel
Visualizing the site and dynam ...... lass I-related receptor, FcRn.
@ast
Visualizing the site and dynam ...... lass I-related receptor, FcRn.
@en
Visualizing the site and dynam ...... lass I-related receptor, FcRn.
@nl
P2093
P1476
Visualizing the site and dynam ...... class I-related receptor, FcRn
@en
P2093
Carlos Vaccaro
Cruz Martinez
Jinchun Zhou
P304
P356
10.4049/JIMMUNOL.172.4.2021
P407
P577
2004-02-01T00:00:00Z