Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.
about
Mechanisms of interstrand DNA crosslink repair and human disordersFine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at workModeling the study of DNA damage responses in miceFanconi anemia and the cell cycle: new perspectives on aneuploidyMechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3Aldehyde dehydrogenase 2 in aplastic anemia, Fanconi anemia and hematopoietic stem cellsA Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous RecombinationFanconi anaemia and the repair of Watson and Crick DNA crosslinksMalfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemiaAdvances in understanding the complex mechanisms of DNA interstrand cross-link repairCan Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant RadioprotectorsDefective endomitosis during megakaryopoiesis leads to thrombocytopenia in Fanca-/- mice.DNA-dependent protease activity of human Spartan facilitates replication of DNA-protein crosslink-containing DNA.Mitochondrial aldehyde dehydrogenase-2 deficiency compromises therapeutic effect of ALDH bright cell on peripheral ischemiaReduced Competitive Repopulation Capacity of Multipotential Hematopoietic Stem Cells in the Bone Marrow of Friend Virus-infected Fv2-resistant Mice.All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis.Dark Hydrazone Fluorescence Labeling Agents Enable Imaging of Cellular Aldehydic Load.The endogenous exposome.Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039.Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agentsMetabolic regulation of stem cell function.Maternal aldehyde elimination during pregnancy preserves the fetal genomeDonor CD4+ Foxp3+ regulatory T cells are necessary for posttransplantation cyclophosphamide-mediated protection against GVHD in mice.Targeting aldehyde dehydrogenase 2: new therapeutic opportunities.The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCLEndogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen.Error-prone translesion synthesis past DNA-peptide cross-links conjugated to the major groove of DNA via C5 of thymidineOxymetholone therapy of fanconi anemia suppresses osteopontin transcription and induces hematopoietic stem cell cycling.A personalized medicine approach for Asian Americans with the aldehyde dehydrogenase 2*2 variantMutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia.Formation, Accumulation, and Hydrolysis of Endogenous and Exogenous Formaldehyde-Induced DNA Damage.Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia.Chromosomal Integrity after UV Irradiation Requires FANCD2-Mediated Repair of Double Strand Breaks.ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis.DNA helicases involved in DNA repair and their roles in cancerChronic alcohol consumption inhibits melanoma growth but decreases the survival of mice immunized with tumor cell lysate and boosted with α-galactosylceramide.The Salivary Microbiome and Oral Cancer Risk: a Pilot Study in Fanconi Anemia.FANCA safeguards interphase and mitosis during hematopoiesis in vivo.ATM and KAT5 safeguard replicating chromatin against formaldehyde damage.Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction.
P2860
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P2860
Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Genotoxic consequences of endo ...... atopoietic stem cell function.
@ast
Genotoxic consequences of endo ...... atopoietic stem cell function.
@en
Genotoxic consequences of endo ...... atopoietic stem cell function.
@nl
type
label
Genotoxic consequences of endo ...... atopoietic stem cell function.
@ast
Genotoxic consequences of endo ...... atopoietic stem cell function.
@en
Genotoxic consequences of endo ...... atopoietic stem cell function.
@nl
prefLabel
Genotoxic consequences of endo ...... atopoietic stem cell function.
@ast
Genotoxic consequences of endo ...... atopoietic stem cell function.
@en
Genotoxic consequences of endo ...... atopoietic stem cell function.
@nl
P2093
P2860
P356
P1433
P1476
Genotoxic consequences of endo ...... atopoietic stem cell function.
@en
P2093
Frederic Langevin
Gerry P Crossan
Juan I Garaycoechea
Ketan J Patel
Maria Daly
Mark J Arends
P2860
P2888
P304
P356
10.1038/NATURE11368
P407
P577
2012-08-26T00:00:00Z
P5875
P6179
1012127257