Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition.
about
A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E epsilon4 allele.The pregnancy hormones human chorionic gonadotropin and progesterone induce human embryonic stem cell proliferation and differentiation into neuroectodermal rosettesNovel therapeutics for Alzheimer's disease: an updateA link between high serum levels of human chorionic gonadotrophin and chorionic expression of its mature functional receptor (LHCGR) in Down's syndrome pregnanciesA Unified Hypothesis of Early- and Late-Onset Alzheimer's Disease PathogenesisThe endocrine dyscrasia that accompanies menopause and andropause induces aberrant cell cycle signaling that triggers re-entry of post-mitotic neurons into the cell cycle, neurodysfunction, neurodegeneration and cognitive diseaseHypothalamic-pituitary-gonadal axis involvement in learning and memory and Alzheimer's disease: more than "just" estrogenLuteinizing hormone receptor mediates neuronal pregnenolone production via up-regulation of steroidogenic acute regulatory protein expressionDown-regulation of serum gonadotropins but not estrogen replacement improves cognition in aged-ovariectomized 3xTg AD female miceAn aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generationChanging the course of Alzheimer's disease: anti-amyloid disease-modifying treatments on the horizon.Genetic ablation of luteinizing hormone receptor improves the amyloid pathology in a mouse model of Alzheimer diseaseDown-regulation of serum gonadotropins is as effective as estrogen replacement at improving menopause-associated cognitive deficits.Elevated mRNA-levels of gonadotropin-releasing hormone and its receptor in plaque-bearing Alzheimer's disease transgenic miceOxidative stress, testosterone, and cognition among Caucasian and Mexican-American men with and without Alzheimer's diseaseTargeting gonadotropins: an alternative option for Alzheimer disease treatment.Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer diseaseNeuroscientists as cartographers: mapping the crossroads of gonadal hormones, memory and age using animal modelsFrontiers in Alzheimer's disease therapeutics.Restricted lateral diffusion of luteinizing hormone receptors in membrane microdomainsEndocrine function in naturally long-living small mammals.Animal models for aberrations of gonadotropin action.Advances in endocrinology of aging research, 2005-2006Hormonal regulation of longevity in mammals.Dysregulation of the hypothalamic-pituitary-gonadal axis with menopause and andropause promotes neurodegenerative senescence.Evaluation of the effects of testosterone and luteinizing hormone on regulation of β-amyloid in male 3xTg-AD miceThe contribution of luteinizing hormone to Alzheimer disease pathogenesisMetabolic and Non-Cognitive Manifestations of Alzheimer's Disease: The Hypothalamus as Both Culprit and Target of PathologyHypothalamic-pituitary-gonadal axis homeostasis predicts longevityLuteinizing hormone: Evidence for direct action in the CNSAndrogen regulation of beta-amyloid protein and the risk of Alzheimer's disease.Leuprolide acetate: a drug of diverse clinical applications.Human chorionic gonadotropin (a luteinizing hormone homologue) decreases spatial memory and increases brain amyloid-beta levels in female rats.An update on the cognitive impact of clinically-used hormone therapies in the female rat: models, mazes, and mechanisms.Is TNF a link between aging-related reproductive endocrine dyscrasia and Alzheimer's disease?Activin receptor signaling regulates prostatic epithelial cell adhesion and viability.Ovariectomy and 17beta-estradiol replacement do not alter beta-amyloid levels in sheep brainTransitional versus surgical menopause in a rodent model: etiology of ovarian hormone loss impacts memory and the acetylcholine system.Road to Alzheimer's disease: the pathomechanism underlying.Neuroendocrinology-based therapy for Alzheimer's disease.
P2860
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P2860
Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition.
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Luteinizing hormone, a reprodu ...... n and amyloid-beta deposition.
@ast
Luteinizing hormone, a reprodu ...... n and amyloid-beta deposition.
@en
Luteinizing hormone, a reprodu ...... n and amyloid-beta deposition.
@nl
type
label
Luteinizing hormone, a reprodu ...... n and amyloid-beta deposition.
@ast
Luteinizing hormone, a reprodu ...... n and amyloid-beta deposition.
@en
Luteinizing hormone, a reprodu ...... n and amyloid-beta deposition.
@nl
prefLabel
Luteinizing hormone, a reprodu ...... n and amyloid-beta deposition.
@ast
Luteinizing hormone, a reprodu ...... n and amyloid-beta deposition.
@en
Luteinizing hormone, a reprodu ...... n and amyloid-beta deposition.
@nl
P2093
P2860
P50
P356
P1476
Luteinizing hormone, a reprodu ...... n and amyloid-beta deposition.
@en
P2093
Albert F Parlow
Craig S Atwood
Ralph N Martins
Richard L Bowen
Tianbing Liu
P2860
P304
20539-20545
P356
10.1074/JBC.M311993200
P407
P577
2004-02-09T00:00:00Z