Molecular insight in the multifunctional activities of Withaferin A.
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Vimentin, colon cancer progression and resistance to butyrate and other HDACisPleiotropic role of HSF1 in neoplastic transformationWithania somnifera root extract inhibits mammary cancer metastasis and epithelial to mesenchymal transitionBenefits of antioxidant supplements for knee osteoarthritis: rationale and realityJNK-NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stressLong-Lasting WNT-TCF Response Blocking and Epigenetic Modifying Activities of Withanolide F in Human Cancer CellsA small molecule inhibitor of NFκB blocks ER stress and the NLRP3 inflammasome and prevents progression of pancreatitis.In vitro discovery of promising anti-cancer drug combinations using iterative maximisation of a therapeutic index.Withaferin A Analogs That Target the AAA+ Chaperone p97.Mechanistic elucidation of the antitumor properties of withaferin a in breast cancer.Alleviation of instant blood-mediated inflammatory reaction in autologous conditions through treatment of human islets with NF-κB inhibitors.Withaferin A Inhibits STAT3 and Induces Tumor Cell Death in Neuroblastoma and Multiple MyelomaCovalent modification of the NF-κB essential modulator (NEMO) by a chemical compound can regulate its ubiquitin binding properties in vitro.Contribution of Cage-Shaped Structure of Physalins to Their Mode of Action in Inhibition of NF-κB ActivationEnhanced biosynthesis of withanolides by elicitation and precursor feeding in cell suspension culture of Withania somnifera (L.) Dunal in shake-flask culture and bioreactor.Effect of Withania somnifera root extract on spontaneous estrogen receptor-negative mammary cancer in MMTV/Neu mice.From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?Ashwagandha attenuates TNF-α- and LPS-induced NF-κB activation and CCL2 and CCL5 gene expression in NRK-52E cells.Anti-cancer activity of withaferin A in B-cell lymphoma.Withaferin A Induces ROS-Mediated Paraptosis in Human Breast Cancer Cell-Lines MCF-7 and MDA-MB-231.Recent Advances in the Development of Antineoplastic Agents Derived from Natural ProductsWithanolide E sensitizes renal carcinoma cells to TRAIL-induced apoptosis by increasing cFLIP degradation.Changes in the leaf proteome profile of Withania somnifera (L.) Dunal in response to Alternaria alternata infectionWithaferin A Inhibits Helicobacter pylori-induced Production of IL-1β in Dendritic Cells by Regulating NF-κB and NLRP3 Inflammasome ActivationWithania somnifera: From prevention to treatment of cancerPharmacologic inhibition of reactive gliosis blocks TNF-α-mediated neuronal apoptosis.Role of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells.Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cellsWITHAFERIN A INDUCES APOPTOSIS IN RAT C6 GLIOMA CELLS THROUGH REGULATING NF-KB NUCLEAR TRANSLOCATION AND ACTIVATION OF CASPASE CASCADE.AshwaMAX and Withaferin A inhibits gliomas in cellular and murine orthotopic modelsTreatment of adult and pediatric high-grade gliomas with Withaferin A: antitumor mechanisms and future perspectives.Withaferin-A Reduces Acetaminophen-Induced Liver Injury in Mice.Withaferin A and its potential role in glioblastoma (GBM).Molecular insights into cancer therapeutic effects of the dietary medicinal phytochemical withaferin A.Natural products triptolide, celastrol, and withaferin A inhibit the chaperone activity of peroxiredoxin I.Molecular docking, QSAR and ADMET studies of withanolide analogs against breast cancerEpigenetic silencing of triple negative breast cancer hallmarks by Withaferin A.Withaferin A Induces Oxidative Stress-Mediated Apoptosis and DNA Damage in Oral Cancer Cells.Withania somnifera and Its Withanolides Attenuate Oxidative and Inflammatory Responses and Up-Regulate Antioxidant Responses in BV-2 Microglial Cells.Concomitant activation of ETS-like transcription factor-1 and Death Receptor-5 via extracellular signal-regulated kinase in withaferin A-mediated inhibition of hepatocarcinogenesis in mice.
P2860
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P2860
Molecular insight in the multifunctional activities of Withaferin A.
description
2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
name
Molecular insight in the multifunctional activities of Withaferin A.
@ast
Molecular insight in the multifunctional activities of Withaferin A.
@en
Molecular insight in the multifunctional activities of Withaferin A.
@nl
type
label
Molecular insight in the multifunctional activities of Withaferin A.
@ast
Molecular insight in the multifunctional activities of Withaferin A.
@en
Molecular insight in the multifunctional activities of Withaferin A.
@nl
prefLabel
Molecular insight in the multifunctional activities of Withaferin A.
@ast
Molecular insight in the multifunctional activities of Withaferin A.
@en
Molecular insight in the multifunctional activities of Withaferin A.
@nl
P2093
P1476
Molecular insight in the multifunctional activities of Withaferin A
@en
P2093
Guy Haegeman
Karen Heyninck
Linde Sabbe
Mary Kaileh
P304
P356
10.1016/J.BCP.2012.08.027
P407
P577
2012-09-06T00:00:00Z