Functional and genetic diversity in the concentrative nucleoside transporter, CNT1, in human populations.
about
Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transportersPharmacogenomic discovery using cell-based modelsThe pharmacogenomics of membrane transporters project: research at the interface of genomics and transporter pharmacology.Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function.Functional genomics of membrane transporters in human populations.Conserved residues F316 and G476 in the concentrative nucleoside transporter 1 (hCNT1) affect guanosine sensitivity and membrane expression, respectively.The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics.Equilibrative nucleoside transporter 1 genotype, cytidine deaminase activity and age predict gemcitabine plasma clearance in patients with solid tumours.Clinical and pharmacogenomic implications of genetic variation in a Southern Ethiopian population.Clinical pharmacology and pharmacogenetics of gemcitabine.Gemcitabine metabolic pathway genetic polymorphisms and response in patients with non-small cell lung cancer.Target selection issues in drug discovery and development.Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs.Ocular toxicity of fludarabine: a purine analogConcentrative nucleoside transporters (CNTs) in epithelia: from absorption to cell signaling.The role of transporters in the pharmacokinetics of orally administered drugs.Human nucleoside transporters: biomarkers for response to nucleoside drugs.Deepwater Horizon crude oil impacts the developing hearts of large predatory pelagic fish.Drug transporter pharmacogenetics in nucleoside-based therapies.Ethnic differences in the metabolism, toxicology and efficacy of three anticancer drugs.Nucleoside transporters: biological insights and therapeutic applications.Hepatocyte nuclear factor-4alpha and bile acids regulate human concentrative nucleoside transporter-1 gene expression.Determinants of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H.Variability of gemcitabine accumulation and its relationship to expression of nucleoside transporters in peripheral blood mononuclear cells.Pharmacogenetic Analysis of the Model-Based Pharmacokinetics of Five Anti-HIV Drugs: How Does This Influence the Effect of Aging?Functional analysis of the human concentrative nucleoside transporter-1 variant hCNT1S546P provides insight into the sodium-binding pocket.Common mechanism underlies repeated evolution of extreme pollution tolerance.
P2860
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P2860
Functional and genetic diversity in the concentrative nucleoside transporter, CNT1, in human populations.
description
2004 nî lūn-bûn
@nan
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Functional and genetic diversi ...... r, CNT1, in human populations.
@ast
Functional and genetic diversi ...... r, CNT1, in human populations.
@en
Functional and genetic diversi ...... r, CNT1, in human populations.
@nl
type
label
Functional and genetic diversi ...... r, CNT1, in human populations.
@ast
Functional and genetic diversi ...... r, CNT1, in human populations.
@en
Functional and genetic diversi ...... r, CNT1, in human populations.
@nl
prefLabel
Functional and genetic diversi ...... r, CNT1, in human populations.
@ast
Functional and genetic diversi ...... r, CNT1, in human populations.
@en
Functional and genetic diversi ...... r, CNT1, in human populations.
@nl
P2093
P356
P1476
Functional and genetic diversi ...... r, CNT1, in human populations.
@en
P2093
Conrad C Huang
Douglas Stryke
Elaine J Carlson
Jennifer H Gray
Kathleen M Giacomini
Michiko Kawamoto
Ryan P Owen
Susan J Johns
Thomas E Ferrin
Thomas J Urban
P304
P356
10.1124/MOL.65.3.512
P577
2004-03-01T00:00:00Z