A repertoire of monoclonal antibodies with human heavy chains from transgenic mice
about
Recent Progress towards Novel EV71 Anti-Therapeutics and VaccinesHuman antibody production in transgenic animalsHigh-affinity IgG antibodies develop naturally in Ig-knockout rats carrying germline human IgH/Igκ/Igλ loci bearing the rat CH regionTwenty years of combinatorial antibody libraries, but how well do they mimic the immunoglobulin repertoire?Mining human antibody repertoires.Human antibodies from transgenic mice.Reprogramming the immune system.Directed evolution of human scFvs in DT40 cells.Preferential selection of receptor-binding variants of influenza virus hemagglutinin by the neutralizing antibody repertoire of transgenic mice expressing a human immunoglobulin mu minigeneA transgenic mouse that expresses a diversity of human sequence heavy and light chain immunoglobulinsSelection of Recombinant Human Antibodies.Human antibodies from transgenic animals.Human immunoglobulin heavy-chain minilocus recombination in transgenic mice: gene-segment use in mu and gamma transcripts.Antibody engineering to develop new antirheumatic therapies.Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal miceExpression of recombinant antibodies.Human monoclonal antibodies to HIV-1 gp140 from mice bearing YAC-based human immunoglobulin transloci.Antibodies generated from human immunoglobulin miniloci in transgenic mice.T-cell specific rearrangement of T-cell receptor beta transgenes in mice.Production of a diverse repertoire of human antibodies in genetically engineered mice.A novel site contributing to growth-arrest-specific gene 6 binding to its receptors as revealed by a human monoclonal antibody.Addressing the Immunogenicity of the Cargo and of the Targeting Antibodies with a Focus on Demmunized Bacterial Toxins and on Antibody-Targeted Human Effector Proteins.Transgenic animals and genetic engineering techniques. Nantes, France, 2-3 July, 2015.Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies.Evolution of Therapeutic Antibodies, Influenza Virus Biology, Influenza, and Influenza Immunotherapy.
P2860
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P2860
A repertoire of monoclonal antibodies with human heavy chains from transgenic mice
description
1989 nî lūn-bûn
@nan
1989 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
A repertoire of monoclonal antibodies with human heavy chains from transgenic mice
@ast
A repertoire of monoclonal antibodies with human heavy chains from transgenic mice
@en
A repertoire of monoclonal antibodies with human heavy chains from transgenic mice
@nl
type
label
A repertoire of monoclonal antibodies with human heavy chains from transgenic mice
@ast
A repertoire of monoclonal antibodies with human heavy chains from transgenic mice
@en
A repertoire of monoclonal antibodies with human heavy chains from transgenic mice
@nl
prefLabel
A repertoire of monoclonal antibodies with human heavy chains from transgenic mice
@ast
A repertoire of monoclonal antibodies with human heavy chains from transgenic mice
@en
A repertoire of monoclonal antibodies with human heavy chains from transgenic mice
@nl
P2093
P2860
P356
P1476
A repertoire of monoclonal antibodies with human heavy chains from transgenic mice
@en
P2093
G T Williams
H M Caskey
M A Surani
M Brüggemann
M S Neuberger
P2860
P304
P356
10.1073/PNAS.86.17.6709
P407
P577
1989-09-01T00:00:00Z