Characterization of antibody responses elicited by human immunodeficiency virus type 1 primary isolate trimeric and monomeric envelope glycoproteins in selected adjuvants
about
A Blueprint for HIV Vaccine DiscoveryStructure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding siteThermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing AntibodiesViremic HIV infected individuals with high CD4 T cells and functional envelope proteins show anti-gp41 antibodies with unique specificity and functionPrepandemic H5N1 influenza vaccine adjuvanted with AS03: a review of the pre-clinical and clinical data.Progress on the induction of neutralizing antibodies against HIV type 1 (HIV-1).Development and evaluation of AS03, an Adjuvant System containing α-tocopherol and squalene in an oil-in-water emulsion.Inhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusion.A monoclonal Fab derived from a human nonimmune phage library reveals a new epitope on gp41 and neutralizes diverse human immunodeficiency virus type 1 strains.Sequestering of the prehairpin intermediate of gp41 by peptide N36Mut(e,g) potentiates the human immunodeficiency virus type 1 neutralizing activity of monoclonal antibodies directed against the N-terminal helical repeat of gp41B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4.Anti-HIV-1 response elicited in rabbits by anti-idiotype monoclonal antibodies mimicking the CD4-binding siteAffinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 neutEarly steps of HIV-1 fusion define the sensitivity to inhibitory peptides that block 6-helix bundle formation.Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection.SERINC5 protein inhibits HIV-1 fusion pore formation by promoting functional inactivation of envelope glycoproteins.Protease cleavage sites in HIV-1 gp120 recognized by antigen processing enzymes are conserved and located at receptor binding sitesComparative immunogenicity of subtype a Human Immunodeficiency Virus type 1 envelope exhibiting differential exposure of conserved neutralization epitopesMulti-Parameter Exploration of HIV-1 Virus-Like Particles as Neutralizing Antibody Immunogens in Guinea Pigs, Rabbits and MacaquesBreadth of neutralizing antibodies elicited by stable, homogeneous clade A and clade C HIV-1 gp140 envelope trimers in guinea pigsHIV infection of macrophages is enhanced in the presence of increased expression of CD163 induced by substance PBinding of HIV-1 gp41-directed neutralizing and non-neutralizing fragment antibody binding domain (Fab) and single chain variable fragment (ScFv) antibodies to the ectodomain of gp41 in the pre-hairpin and six-helix bundle conformationsA limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals.PD 404,182 is a virocidal small molecule that disrupts hepatitis C virus and human immunodeficiency virus.Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates.Immunization with wild-type or CD4-binding-defective HIV-1 Env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus.Specificity of the autologous neutralizing antibody responseMucosal and systemic anti-HIV immunity controlled by A20 in mouse dendritic cellsNeutralizing antibody responses in macaques induced by human immunodeficiency virus type 1 monovalent or trivalent envelope glycoproteins.Comparison of neutralizing antibody responses elicited from highly diverse polyvalent heterotrimeric HIV-1 gp140 cocktail immunogens versus a monovalent counterpart in rhesus macaquesDense display of HIV-1 envelope spikes on the lambda phage scaffold does not result in the generation of improved antibody responses to HIV-1 Env.Mirabamides E-H, HIV-inhibitory depsipeptides from the sponge Stelletta clavosaSub-inhibitory concentrations of human α-defensin potentiate neutralizing antibodies against HIV-1 gp41 pre-hairpin intermediates in the presence of serum.Selected HIV-1 Env trimeric formulations act as potent immunogens in a rabbit vaccination model.Structure-based vaccine design in HIV: blind men and the elephant?Antibody responses elicited in macaques immunized with human immunodeficiency virus type 1 (HIV-1) SF162-derived gp140 envelope immunogens: comparison with those elicited during homologous simian/human immunodeficiency virus SHIVSF162P4 and heteroloHighly potent chimeric inhibitors targeting two steps of HIV cell entryNeutralizing and other antiviral antibodies in HIV-1 infection and vaccination.Synergistic inhibition of HIV-1 envelope-mediated membrane fusion by inhibitors targeting the N and C-terminal heptad repeats of gp41.Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque
P2860
Q26829865-CBD5817E-EFDA-4FE2-942B-75BDA536C5CFQ27316899-5AC18A04-AFF7-4B9D-87A9-96E3122549F0Q28553360-EC5E0109-7B3B-4462-885E-85ADB58341EDQ28732293-8B89315C-E260-46D3-BE94-D79AF24613A7Q30378421-3BE9C849-99E7-4890-94E1-3A55F56F5A39Q30379200-E421672A-1531-4252-B4FB-0D4C99378F16Q30413695-62D81A84-7335-4F6F-BBF4-9B4FB8689897Q30507959-F7807D9F-5BE3-4970-AA59-D13C593FF031Q33300529-4DD0ED35-AC82-46F4-8DEF-EA2D48E948AAQ33356323-1E95D880-09D2-4F9F-9C73-C0449F96B8E9Q33373664-8839B6B3-EF74-476E-8F84-85D1CBC0C198Q33377024-005DA26F-4CC2-406D-A8A8-9A52DC0A889CQ33495440-31015ABE-0182-4397-9496-AD852ECD6053Q33504556-38112E81-97DE-4996-A263-227DC5204499Q33504604-B2195B84-66A3-42F8-84AF-633B8FA95390Q33567639-76FC2C11-8772-4FF0-9DF8-B29D101202A9Q33614461-1FBDCE02-62B0-4137-9386-32AA0FAEAAFAQ33648910-1871322D-EECE-4659-BFEA-65AE44E70AF7Q33683203-A60C77A9-B4CB-4A0B-8349-4413111E23C0Q33725679-82C07DD1-0F96-4FDD-89F9-015370CE9329Q33750864-C14F78D3-5E1C-4F4C-881B-0634A23F25ACQ34020570-6468735E-9653-4768-8401-9DEEB297E94FQ34047445-CF2C2D68-76FD-4BB9-AE61-CE01BBDDB6E1Q34074331-6C9E793F-1E2A-4AD0-9BE6-DCE944D390F9Q34096530-DCF5EE24-C780-4FF9-AFD8-DEC88CD7D429Q34120088-4E928961-D89B-447C-A946-39B1C6F62B3EQ34415389-3E074CE3-C86D-4326-B278-9EC60F803731Q34519838-49B4270F-9DBD-43D8-B4B4-3D5AFD3B45ADQ34637968-3EF75876-B40A-4D3E-A623-4545F6AA80A0Q34663118-CE15D8C3-0701-4B3F-93C2-AFCFC5965A71Q34706815-30C85FC4-502C-4121-AF82-0997B69EA99AQ34769803-AFDC5804-491A-4B83-A5EF-7BFB308CDED6Q34778515-D70641E3-788D-41AD-86D4-F4ACD261EC0FQ34984724-35C40941-37D4-42CA-A20B-231EFF7EC265Q34987048-9950FF04-D776-4CF9-B920-44F5D307A322Q35024202-5E0E07F4-A4E2-4895-8DF6-0EE1BE833BA7Q35150195-374EF98E-21A9-4BE7-B5B5-31924014C9E4Q35208657-A04FB9FE-41A6-497D-B067-A4970C7C2BBCQ35616634-5481F147-8B53-4B6B-BDDA-80E41913E507Q35647701-3F8F8B46-AB33-43C7-87C2-FD2F02C58AB0
P2860
Characterization of antibody responses elicited by human immunodeficiency virus type 1 primary isolate trimeric and monomeric envelope glycoproteins in selected adjuvants
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Characterization of antibody r ...... proteins in selected adjuvants
@ast
Characterization of antibody r ...... proteins in selected adjuvants
@en
Characterization of antibody r ...... proteins in selected adjuvants
@nl
type
label
Characterization of antibody r ...... proteins in selected adjuvants
@ast
Characterization of antibody r ...... proteins in selected adjuvants
@en
Characterization of antibody r ...... proteins in selected adjuvants
@nl
prefLabel
Characterization of antibody r ...... proteins in selected adjuvants
@ast
Characterization of antibody r ...... proteins in selected adjuvants
@en
Characterization of antibody r ...... proteins in selected adjuvants
@nl
P2093
P2860
P1433
P1476
Characterization of antibody r ...... proteins in selected adjuvants
@en
P2093
P2860
P304
P356
10.1128/JVI.80.3.1414-1426.2006
P407
P577
2006-02-01T00:00:00Z