Survival motor neuron gene transcript analysis in muscles from spinal muscular atrophy patients.
about
Gemin4. A novel component of the SMN complex that is found in both gems and nucleoliIntragenic telSMN mutations: frequency, distribution, evidence of a founder effect, and modification of the spinal muscular atrophy phenotype by cenSMN copy number.The survival motor neuron protein forms soluble glycine zipper oligomersHeterogeneity of subcellular localization and electrophoretic mobility of survival motor neuron (SMN) protein in mammalian neural cells and tissuesA SMN missense mutation complements SMN2 restoring snRNPs and rescuing SMA miceSpinal muscular atrophy: from gene discovery to clinical trialsSpinal muscular atrophy: development and implementation of potential treatmentsApplicability of histone deacetylase inhibition for the treatment of spinal muscular atrophySplicing therapy for neuromuscular diseaseAn in vivo reporter system for measuring increased inclusion of exon 7 in SMN2 mRNA: potential therapy of SMASynergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophyEarly heart failure in the SMNDelta7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN deliveryA single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophyPostsymptomatic restoration of SMN rescues the disease phenotype in a mouse model of severe spinal muscular atrophy.Molecular determinants of survival motor neuron (SMN) protein cleavage by the calcium-activated protease, calpainEnhancement of SMN2 exon 7 inclusion by antisense oligonucleotides targeting the exon.Conserved genes act as modifiers of invertebrate SMN loss of function defectsSpinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?Mouse survival motor neuron alleles that mimic SMN2 splicing and are inducible rescue embryonic lethality early in development but not lateA multi-source approach to determine SMA incidence and research ready populationSpecific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN).Treatment of spinal muscular atrophy by sodium butyrate.SMN requirement for synaptic vesicle, active zone and microtubule postnatal organization in motor nerve terminalsSplicing of the Survival Motor Neuron genes and implications for treatment of SMAAssays for the identification and prioritization of drug candidates for spinal muscular atrophyTemporal requirement for high SMN expression in SMA miceA single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouseTherapeutic strategies for the treatment of spinal muscular atrophy.SMN-inducing compounds for the treatment of spinal muscular atrophy.Antisense oligonucleotides for the treatment of spinal muscular atrophy.Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2.A multicopy transcription-repair gene, BTF2p44, maps to the SMA region and demonstrates SMA associated deletions.A multi-exon-skipping detection assay reveals surprising diversity of splice isoforms of spinal muscular atrophy genes.Improved antisense oligonucleotide design to suppress aberrant SMN2 gene transcript processing: towards a treatment for spinal muscular atrophyTargeting SR proteins improves SMN expression in spinal muscular atrophy cells.Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compoundsRepair of pre-mRNA splicing: prospects for a therapy for spinal muscular atrophy.Spinal muscular atrophy: diagnosis and management in a new therapeutic eraSelective vulnerability of spinal and cortical motor neuron subpopulations in delta7 SMA mice.Treatment of spinal muscular atrophy cells with drugs that upregulate SMN expression reveals inter- and intra-patient variability.
P2860
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P2860
Survival motor neuron gene transcript analysis in muscles from spinal muscular atrophy patients.
description
1995 nî lūn-bûn
@nan
1995 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Survival motor neuron gene tra ...... nal muscular atrophy patients.
@ast
Survival motor neuron gene tra ...... nal muscular atrophy patients.
@en
Survival motor neuron gene tra ...... nal muscular atrophy patients.
@nl
type
label
Survival motor neuron gene tra ...... nal muscular atrophy patients.
@ast
Survival motor neuron gene tra ...... nal muscular atrophy patients.
@en
Survival motor neuron gene tra ...... nal muscular atrophy patients.
@nl
prefLabel
Survival motor neuron gene tra ...... nal muscular atrophy patients.
@ast
Survival motor neuron gene tra ...... nal muscular atrophy patients.
@en
Survival motor neuron gene tra ...... nal muscular atrophy patients.
@nl
P2093
P50
P356
P1476
Survival motor neuron gene tra ...... inal muscular atrophy patients
@en
P2093
M Gennarelli
P304
P356
10.1006/BBRC.1995.2135
P407
P50
P577
1995-08-01T00:00:00Z