Activation of protein C by the thrombin-thrombomodulin complex: cooperative roles of Arg-35 of thrombin and Arg-67 of protein C
about
Crystal Structure of Thrombin Bound to the Uncleaved Extracellular Fragment of PAR1Exposure of R169 controls protein C activation and autoactivationRegulation of the protein C anticoagulant and antiinflammatory pathways.Kinetic dissection of the pre-existing conformational equilibrium in the trypsin fold.Thrombin activity propagates in space during blood coagulation as an excitation wave.Salmon-derived thrombin inhibits development of chronic pain through an endothelial barrier protective mechanism dependent on APC.Thrombin.Mutagenesis studies toward understanding allostery in thrombin.Functional role of O-linked and N-linked glycosylation sites present on the activation peptide of factor X.Identification of a specific exosite on activated protein C for interaction with protease-activated receptor 1.Engineering a disulfide bond to stabilize the calcium-binding loop of activated protein C eliminates its anticoagulant but not its protective signaling properties.Mutations in the fourth EGF-like domain affect thrombomodulin-induced changes in the active site of thrombin.Paradoxical bleeding and thrombotic episodes of dysprothrombinaemia due to a homozygous Arg382His mutation.Expression and functional characterisation of natural R147W and K150del variants of protein C in the Chinese population.
P2860
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P2860
Activation of protein C by the thrombin-thrombomodulin complex: cooperative roles of Arg-35 of thrombin and Arg-67 of protein C
description
2006 nî lūn-bûn
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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Activation of protein C by the ...... rombin and Arg-67 of protein C
@ast
Activation of protein C by the ...... rombin and Arg-67 of protein C
@en
Activation of protein C by the ...... rombin and Arg-67 of protein C
@nl
type
label
Activation of protein C by the ...... rombin and Arg-67 of protein C
@ast
Activation of protein C by the ...... rombin and Arg-67 of protein C
@en
Activation of protein C by the ...... rombin and Arg-67 of protein C
@nl
prefLabel
Activation of protein C by the ...... rombin and Arg-67 of protein C
@ast
Activation of protein C by the ...... rombin and Arg-67 of protein C
@en
Activation of protein C by the ...... rombin and Arg-67 of protein C
@nl
P2093
P2860
P356
P1476
Activation of protein C by the ...... rombin and Arg-67 of protein C
@en
P2093
Alireza R Rezaie
Chandrashekhara Manithody
Likui Yang
P2860
P304
P356
10.1073/PNAS.0507700103
P407
P577
2006-01-17T00:00:00Z